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** Ptolemy IV Philopater ( 222 BC – 204 BC ) and his wife Arsinoe III
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** and Ptolemy
** Ptolemy III, King of Egypt, who has reunited Egypt and Cyrenaica and successfully waged the Third Syrian War against the Seleucid kingdom
** Berenice II, queen of Egypt, daughter of Magas, King of Cyrenaica ( in modern Libya ), whose marriage to Ptolemy III Euergetes has reunited her country with Egypt ( b. c. 267 BC )
** September 28 – Pompey the Great is assassinated on orders of King Ptolemy of Egypt after landing in Egypt ( may have occurred September 29, records unclear ).
** December – Battle in Alexandria, Egypt between the forces of Caesar and his ally Cleopatra VII and those of rival King Ptolemy XIII of Egypt and Queen Arsinoe IV.
** Ptolemy IV Philopator, Greek king of Egypt who has reigned from 221 BC and under whose weak and incompetent rule, heavily influenced by his favourites, much of Ptolemaic Syria has been lost and native uprisings have begun to disturb the internal stability of the country ( b. c. 238 BC )
** Arsinoe III, queen of Egypt, sister and wife of the King Ptolemy IV ( assassinated ) ( b. c. 246 BC )
** Cleopatra I Syra, queen of Egypt from 193 BC, wife of Ptolemy V Epiphanes and regent for her young son, Ptolemy VI Philometor ( b. c. 204 BC )
** Berenice ( Seleucid queen ), daughter of Ptolemy II of Egypt and wife of Seleucid monarch Antiochus II Theos
** Berenice II of Egypt, daughter of Magas of Cyrene, wife of Ptolemy III of Egypt and traditional namesake of the constellation Coma Berenices
** Berenice III of Egypt, daughter of Ptolemy IX of Egypt ; she first married Ptolemy X of Egypt, and later Ptolemy XI of Egypt
** and IV
** In the Star Trek: Voyager episode " One Small Step ", USS Voyager discovers the fate of Ares IV, one of the first manned expeditions to Mars in 2032.
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