* 1492 – Spain gives Christopher Columbus his commission of exploration.

* 1492 – Christopher Columbus sets sail from Palos de la Frontera, Spain.

Andrea Alciato ( May 8, 1492 – January 12, 1550 ), commonly known as Alciati ( Andreas Alciatus ), was an Italian jurist and writer.

* 1492 – Spain and Christopher Columbus sign the Capitulations of Santa Fe for his voyage to Asia to acquire spices.

Bayezid II was born in Dimetoka Palace ( now Didymoteicho ) in Thrace as the son of Mehmed II ( 1432 – 81 ) and Valide Sultan Mükrime Hatun, the daughter of Süleyman Bey, the sixth ruler of Dulkadirids, who died in 1492.

Eventually, the Knights handed Cem over to Pope Innocent VIII ( 1484 – 1492 ).

* Casimir IV Jagiellon ( 1427 – 1492 ), Polish king

* 1492 – Christopher Columbus becomes the first European to set foot on the island of Hispaniola, now Haiti and the Dominican Republic.

* 1549 – Marguerite of Navarre, wife of Henry II of Navarre ( b. 1492 )

* 1492 31 March – After conquering Granada, the Catholic Monarchs sign the Alhambra decree ordering the expulsion of the Jews from Spain, to be take effect from 31 July 1492.

* 1492 – Reconquista: the emirate of Granada, the last Moorish stronghold in Spain, surrenders.

* 1492 – Ferdinand and Isabella The Catholic Monarchs enter Granada, completing the Reconquista.

* 1492 – The first grammar of the Spanish language is presented to Queen Isabella I.

Lorenzo de ' Medici ( 1 January 1449 – 9 April 1492 ) was an Italian statesman and de facto ruler of the Florentine Republic during the Italian Renaissance.

* 1492 – Queen Isabella of Castille issues the Alhambra decree, ordering her 150, 000 Jewish subjects to convert to Christianity or face expulsion.

At this time, Michelangelo sculpted the reliefs Madonna of the Steps ( 1490 – 1492 ) and Battle of the Centaurs ( 1491 – 1492 ).

Following the breakup of Mali a local leader named Sonni Ali ( 1464 – 1492 ) founded the Songhai Empire in the region of middle Niger and the western Sudan and took control of the trans-Saharan trade.

* 1492 – Peace of Etaples between Henry VII and Charles VIII.

* 1492 – Jami, Persian poet ( b. 1414 )

* 1492 – The Ensisheim meteorite, the oldest meteorite with a known date of impact, strikes the earth around noon in a wheat field outside the village of Ensisheim, Alsace, France.

After the discovery of the West Indies by Christopher Columbus in 1492, the Spanish term Antillas was assigned to the lands ; stemming from this, " Sea of the Antilles " is a common alternative name for the Caribbean Sea in various European languages.

After his death in 1492, his heirs were deposed by General Muhammad Ture, a Muslim of Soninke origins.

After the expulsion of the Jews from Spain in 1492, women became virtually the only source of Jewish ritual and tradition in the Catholic world in a phenomenon known as crypto-Judaism.

After the Reconquista ( reconquest ) by the Reyes Católicos (" Catholic Monarchs ") in 1492, some portions were used by the Christian rulers.

After the 1492 Alhambra decree, which resulted in the majority of Granada's Jewish population being expelled, the Jewish quarter ( ghetto ) was demolished to make way for new Catholic and Castilian institutions and uses.

After 1492 the discovery of the West Indies by Christopher Columbus rendered desirable a delimitation of the Spanish and Portuguese spheres of exploration.

After 1492, this focus shifted to the Atlantic Ocean by routes south around the Cape of Good Hope, and by trans-Atlantic trade.

After the expulsion of Jews and Muslims in 1492 from Spain and Portugal, conversos continued to be suspect in times of social strain.

After the 1492 arrival of Christopher Columbus's expedition in what was later called the West Indies, the European powers realized that the dispersed lands comprised an extensive archipelago enclosing the Caribbean and the Gulf of Mexico.

After Christopher Columbus reached the New World in 1492 and brought the first samples of Capsicum frutescens, the name malagueta was then taken to the new chilli " pepper ".

After arriving at Cuba, which he supposed to be the Asian coast, Columbus sent de Torres and the sailor Rodrigo de Jerez for an expedition inland on November 2, 1492.

After the expulsion of the Islamic rule from Spain during the reconquista which ended by 1492, many prominent rabbis found their way to Safed, among them the Kabbalists Isaac Luria and Moshe Kordovero ; Joseph Caro, the author of the Shulchan Aruch and Shlomo Halevi Alkabetz, composer of the Sabbath hymn " Lecha Dodi ".

After the fall of the Byzantine Empire in 1453 and the expulsion of Jews from Spain ( 1492 ) and Portugal ( 1498 ), many Jews made their way to the Holy Land.

After 10 years of many battles the Granada War ended in 1492 when the Emir Boabdil surrendered the keys of the Alhambra Palace in Granada to the Castilian soldiers.

After the 1492 death of Konrad Biały Młodszy, last of the local Piast dynasty, the duchy was sold to the Bohemian Poděbrady dynasty.

After their expulsion from Spain in 1492, Sephardic Jews settled in Thessaloniki ( known in this period as Salonica or Selanik ), which became the main Jewish centre of the empire.

After the expulsion of the Sephardi Jews from Spain in 1492, the exiles took the leading position in most Arab and Ottoman countries, and the local pronunciation of Hebrew assimilated to Sephardi Hebrew in many respects, in particular the pronunciation of the vowels.

After 1492, when the north Atlantic Ocean began to be routinely sailed, and became more accurately mapped, depictions of Antillia gradually disappeared.

After Lorenzo's death in 1492, Giuliano visited Loreto, and built the dome of the Basilica of the Madonna, in spite of serious difficulties arising from its defective piers, which were already built.

After the defeat of the Muslims during the Christian Reconquista (" Reconquest ") period between 1000 and 1492, Spain became an almost entirely Roman Catholic country.

After the Hundred Years ' War ( 1337 – 1453 ) and the Treaty of Picquigny ( 1475 ) – its official end date – in 1492 and 1493, Charles VIII of France signed three additional treaties with Henry VII of England, Maximilian I of Habsburg, and Ferdinand II of Aragon respectively at Étaples ( 1492 ), Senlis ( 1493 ) and in Barcelona ( 1493 ).