* 1667 – Francesco Borromini, Swiss architect, designed San Carlo alle Quattro Fontane and Sant ' Agnese in Agone ( b. 1599 )

* 1599 – Méric Casaubon, English scholar ( d. 1671 )

* 1599 – Nine Years ' War: Battle of Curlew Pass – Irish forces led by Hugh Roe O ' Donnell successfully ambush English forces, led by Sir Conyers Clifford, sent to relieve Collooney Castle.

* 1565 – Cornelis de Houtman, Dutch explorer ( d. 1599 )

* 1599 – Henry Wallop, English statesman

* 1599 – Maeda Toshiie, Japanese general ( b. 1538 )

* 1599 – Oliver Cromwell, English military and politician ( d. 1658 )

* 1577 – Beatrice Cenci, Italian noblewoman ( d. 1599 )

Francesco Borromini, byname of Francesco Castelli ( 25 September 1599 – 3 August 1667 ), was an architect from Ticino who, with his contemporaries Gian Lorenzo Bernini and Pietro da Cortona, was a leading figure in the emergence of Roman Baroque architecture.

* 1599 – Pope Alexander VII ( d. 1667 )

* 1538 – Maeda Toshiie, Japanese general ( d. 1599 )

John Alden ( 1599 – September 12, 1687 ) is said to be the first person from the Mayflower to set foot on Plymouth Rock in 1620.

* 1671 – Méric Casaubon, English scholar ( b. 1599 )

* Maria Eleonora of Brandenburg ( 11 November 1599 – 28 March 1655 ).

The Kazakh Khanate is described in historical texts such as the Tarikh-i-Rashidi ( 1541 – 1545 ) by Muhammad Haidar Dughlat, and Zhamigi-at-Tavarikh ( 1598 – 1599 ) by Kadyrgali Kosynuli Zhalayir.

Zanabazar ( 1635 – 1723 ), Zaya Pandita ( 1599 – 1662 ) and Danzanravjaa ( 1803 – 1856 ) are among the most famous Mongolian holy men.

* 1667 – Pope Alexander VII ( b. 1599 )

Maria Eleonora of Brandenburg ( 11 November 1599 – 28 March 1655 ) was a German princess and queen consort of Sweden.

* 1599 – Anthony van Dyck, Flemish painter ( d. 1641 )

* 1660 – Lucy Hay, Countess of Carlisle, English socialite ( b. 1599 )

* 1599 – Francisco Guerrero, Spanish composer ( b. 1528 )

** Denzil Holles, 1st Baron Holles, English statesman and writer ( b. 1599 )

Denzil Holles, 1st Baron Holles PC ( 31 October 1599 – 17 February 1680 ) was an English statesman and writer, best known as one of the five members of parliament whom King Charles I of England attempted to arrest in 1642.

* August 21 – Henry Grey, 1st Earl of Stamford, English soldier ( b. c. 1599 )

Joan Apsley ( 1578 – 14 December 1599 ), the maiden name of Joan Boyle, was the wife of Richard Boyle, 1st Earl of Cork.

* Colin Campbell, 1st Baronet ( b. 1599 ) ( only son of the younger son of the 6th Earl )

George Gordon, 2nd Marquess of Huntly ( 1592 – March 1649 ), styled Earl of Enzie from 1599 to 1636, eldest son of George Gordon, 1st Marquess of Huntly by Lady Henrietta Stewart, daughter of Esmé Stewart, 1st Duke of Lennox, was brought up in England as a Protestant, and later created Viscount Aboyne by Charles I.

* Thomas Bruce, 1st Earl of Elgin ( 1599 – 1663 )

* John Byron, 1st Baron Byron ( 1599 – 1652 )

* Thomas Bruce, 1st Earl of Elgin, 3rd Lord Kinloss ( 1599 – 1663 )

* Sir John Curzon, 1st Baronet ( c. 1599 – 1686 )

* Robert Digby, 1st Baron Digby ( c. 1599 – 1642 )

Henry Grey, 1st Earl of Stamford ( c. 1599 – 21 August 1673 ), known as the Lord Grey of Groby from 1614 to 1628, was an English nobleman and military leader.

* Conyers Darcy, 1st Earl of Holderness ( 1599 – 1689 )

Lucy ( 1599 / 1600-5 November 1660 ), married as his second wife James Hay, 1st Earl of Carlisle.

John Byron, 1st Baron Byron ( 1599, Newstead, Nottinghamshire – 23 August 1652 ) was an English Royalist and supporter of Charles I during the English Civil War.

* Thomas Smythe, 1st Viscount Strangford ( 1599 – 1635 )

* John Gordon, 1st Viscount of Kenmure ( 1599 – 1634 )

Sir John Gordon, 1st Viscount of Kenmure ( 1599 – 1634 ) was a Scottish nobleman, renowned Presbyterian, and founder of the town of New Galloway.

Several tombs of the Waldegrave family are found within the structure, including a monument 14 feet high with a cornice supported by six pillars of the Corinthian order, beneath which lie full length figures of Sir Edward Waldegrave ( knighted in 1553, at the coronation of Queen Mary, died in the Tower of London on 1st September 1561 ) and his wife Lady Frances Waldegrave née Neville ( died 1599 ).

These were the Lords Cobham: William Brooke, 10th Baron Cobham ( died 6 March 1597 ), was Warden of the Cinque Ports ( 1558 – 97 ), Knight of the Order of the Garter ( 1584 ), and member of the Privy Council ( 1586 – 97 ); his son Henry Brooke, 11th Baron Cobham, was granted the paternal post of Warden of the Cinque Ports upon his father's death, and made a Knight of the Order of the Garter in 1599.

* Robert Petre, 3rd Baron Petre ( 1599 – 1638 )

* Gerald de Courcy, 17th Baron Kingsale ( d. 1599 )

These were the Lords Cobham: William Brooke, 10th Baron Cobham ( died 6 March 1597 ), was Warden of the Cinque Ports ( 1558 – 97 ), Knight of the Order of the Garter ( 1584 ), and member of the Privy Council ( 1586 – 97 ); his son Henry Brooke, 11th Baron Cobham, was granted the paternal post of Warden of the Cinque Ports upon his father's death, and made a Knight of the Order of the Garter in 1599.

* John Power, 5th Baron Power ( c. 1599 – 1661 )

In 1599 Baron de Mafflier ( by which name he was known at court ) renounced the world and entered the Capuchin priory of Orléans.