* 1672 – André Cardinal Destouches, French composer ( d. 1749 )

* 1749 – Johann Wolfgang von Goethe, German writer and scientist ( d. 1832 )

* 1749 – First performance of Handel's Music for the Royal Fireworks in Green Park, London.

The spelling and names in both the 1609 – 1610 Douay Old Testament ( and in the 1582 Rheims New Testament ) and the 1749 revision by Bishop Challoner ( the edition currently in print used by many Catholics, and the source of traditional Catholic spellings in English ) and in the Septuagint ( an ancient translation of the Old Testament in to Greek, which is widely used by the Eastern Orthodox instead of the Masoretic text ) differ from those spellings and names used in modern editions which are derived from the Hebrew Masoretic text.

* Dominique Joseph Garat ( 1749 – 1833 ), writer and politician

It was Pierre-Simon Laplace ( 1749 – 1827 ) who introduced a general version of the theorem and used it to approach problems in celestial mechanics, medical statistics, reliability, and jurisprudence.

Three of five siblings survived to adulthood, Denise Diderot ( 1715 – 1797 ) and their youngest brother Pierre-Didier Diderot ( 1722 – 1787 ), and finally their sister Angélique Diderot ( 1720 – 1749 ).

Edward Anthony Jenner, FRS ( 17 May 1749 – 26 January 1823 ) was an English physician and scientist from Berkeley, Gloucestershire, who was the pioneer of smallpox vaccine.

A bio-bibliography of Edward Jenner, 1749 – 1823.

Rabbi Chaim Volozhin ( Lithuania 1749 – 1821 ) reports in an introduction to Siphra Dzeniouta ( 1818 ) that he once presented to his teacher, the Vilna Gaon, ten different versions of a certain passage in the Sefer Yetzira and asked the Gaon to determine the correct text.

* 1749 – 1754 – Liutenant General Humphrey Bland is the Governor of Gibraltar.

Hans Egede's Hope Colony was organized under the auspices of the Bergen Greenland Company prior to its bankruptcy in 1727 ; it was succeeded by the merchant Jacob Severin ( 1733 – 1749 ), the General Trade Company ( Det almindelige Handelskompagni ; 1749 – 1774 ), and finally the Royal Greenland Trading Department ( KGH ; 1776 – 1908 ).

* Pierre-Simon Laplace 1749 – 1827, Paris ( France )

The movement, from 1772 until 1805, involved Herder as well as polymath Johann Wolfgang von Goethe ( 1749 – 1832 ) and Friedrich Schiller ( 1759 – 1805 ), a poet and historian.

German artists and intellectuals, heavily influenced by the French Revolution and by the great German poet and writer Johann Wolfgang von Goethe ( 1749 – 1832 ), turned to Romanticism after a period of Enlightenment.

File: Goethe ( Stieler 1828 ). jpg | Johann Wolfgang von Goethe ( 1749 – 1832 )

Through the influence of Johann Wolfgang von Goethe ( 1749 – 1832 ), the ghazal became very popular in Germany during the 19th century ; the form was used extensively by Friedrich Rückert ( 1788 – 1866 ) and August von Platen ( 1796 – 1835 ).

File: Georg Friedrich Händel. jpg | Thomas Hudson George Frideric Händel, ( 1749 )

Friedrich Müller ( 13 January 1749 – 23 April 1825 ), German poet, dramatist and painter from the Electorate of the Palatinate, is best known for his slightly sentimental prose idylls on country life.

* Maler Müller ( 1749 – 1825 ), painter

* Maler Müller ( painter, called Maller-Müller, 1749 – 1825 ),, German poet, dramatist and painter

By Thomas Hudson ( painter ) | Thomas Hudson ( 1749 )

Thomas Hudson ( painter ) | Thomas Hudson George Frideric Händel, ( 1749 )

** Maria Oriana Galli-Bibiena, Italian painter ( d. 1749 )

* November 25 – Pierre Subleyras, French painter ( d. 1749 )

* Jean Humbert ( painter ) ( 1734 – 1749 ), Dutch painter

The appointment of Mengs in 1749 as first painter to Frederick Augustus, elector of Saxony, did not prevent his spending much time in Rome, where he had married Margarita Guazzi who had sat for him as a model in 1748, and abjured the Protestant faith, and where he became in 1754 director of the Vatican school of painting, nor did this hinder him on two occasions from obeying the call of Charles III of Spain to Madrid.

It was damaged in the fire that destroyed the Alcázar in 1734, and was restored by court painter Juan García de Miranda ( 1677 – 1749 ).

* Thomas Burke ( artist ) ( 1749 – 1815 ), Irish engraver and painter known for mezzotint

He was the eldest son of Dr. Martin Tupper ( 1780 – 1844 ), a medical man highly esteemed in his day who came from an old Guernsey family, by his wife Ellin Devis Marris ( d. 1847 ), only child of Robert Marris ( 1749 – 1827 ), a landscape painter ( by his wife Frances, daughter of the artist Arthur Devis ).

Thomas Hudson ( painter ) | Thomas Hudson, Portrait of John Byng, 1749

Jan Frans van Bloemen ( baptized 12 May 1662-buried 13 June 1749 ) was a Flemish landscape painter of the Baroque period.

Jan van Huysum, also spelled Huijsum, ( April 15, 1682, Amsterdam-February 8, 1749, Amsterdam ) was a Dutch painter.

Pierre Subleyras ( November 25, 1699 – May 28, 1749 ) was a French painter, active during the late-Baroque and early-Neoclassic period, mainly in Italy.

Adélaïde Labille-Guiard ( 11 April 1749 – 24 April 1803 ), also known as Adélaïde Labille-Guiard des Vertus, was a French miniaturist and portrait painter.

Thomas Daniell ( 1749 – 19 March 1840 ) was an English landscape painter.

Thomas Daniell was born in 1749 at the Chertsey inn, kept by his father, and was apprenticed to an heraldic painter.

In 1749, Thomas Frye, a portrait painter, took out a patent on a porcelain containing bone ash.

* Thomas Roberts ( painter ) ( 1749 – 1778 ), Irish landscape painter

* 1749 – Vittorio Alfieri, Italian dramatist ( d. 1803 )

* October 8-Vittorio Alfieri, dramatist ( born 1749 )

* August 16-Catherine Trotter Cockburn, novelist, dramatist and philosopher ( died 1749 )

** Thomas Southerne, dramatist ( died 1749 )

Count Vittorio Alfieri ( 16 January 1749 – 8 October 1803 ) was an Italian dramatist, considered the " founder of Italian tragedy.

Camillo Federici ( 9 April 1749 – 23 December 1802 ) was an Italian dramatist and actor.

Catharine Trotter Cockburn ( 16 August 1679 – 11 May 1749 ) was a novelist, dramatist, and philosopher.