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* Antipsychotics ( Haloperidol, chlorpromazine, clozapine, etc.
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Antipsychotics and chlorpromazine
Antipsychotics are not recommended for benzodiazepine withdrawal ( or other CNS depressant withdrawal states ) especially clozapine, olanzapine or low potency phenothiazines e. g. chlorpromazine as they lower the seizure threshold and can worsen withdrawal effects ; if used extreme caution is required.
Antipsychotics and clozapine
Antipsychotics and .
Antipsychotics are broadly divided into two groups, the typical or first-generation antipsychotics and the atypical or second-generation antipsychotics.
Antipsychotics might also be used to counter psychosis associated with a wide range of other diagnoses, such as psychotic depression.
Antipsychotics have also been increasingly used off-label in cases of dementia in older people, and for various disorders and difficulties in children and teenagers.
Antipsychotics are sometimes used as part of compulsory treatment via inpatient ( hospital ) commitment or outpatient commitment.
Antipsychotics are among the biggest selling and most profitable of all drugs, generating $ 22 billion in global sales in 2008.
* Antipsychotics, particularly atypicals, appear to cause diabetes mellitus and fatal diabetic ketoacidosis, especially ( in US studies ) in African Americans.
* Antipsychotics increase the likelihood of a fatal heart attack, with the risk of death increasing with dose and the length of time on the drug.
* Antipsychotics are generally a first-line treatment for delirium ; however, when delirium is caused by alcohol or sedative hypnotic withdrawal, benzodiazepines are a first-line treatment.
Antipsychotics are sometimes employed but require caution as they can worsen symptoms and have serious adverse effects.
Antipsychotics should be used with care as they can worsen catatonia and are the cause of neuroleptic malignant syndrome, a dangerous condition that can mimic catatonia and requires immediate discontinuation of the antipsychotic.
Antipsychotics, however, fail to significantly ameliorate the negative symptoms and cognitive dysfunction.
Antipsychotics are drugs used to treat various symptoms of psychosis, such as those caused by psychotic disorders or schizophrenia.
Antipsychotics are also used as mood stabilizers in the treatment of bipolar disorder, even if no symptoms of psychosis are present.
Antipsychotics are not effective against dissociatives such as PCP, DXM and Ketamine, and should not be used if these drugs are involved.
Antipsychotics, particularly haloperidol, are the most commonly used drugs for delirium and the most studied.
Antipsychotics, however, fail to significantly ameliorate the negative symptoms and cognitive dysfunction.
Haloperidol and chlorpromazine
MAO Inhibitors, chlorpromazine ( Thorazine ), Haldol ( Haloperidol ) and the tranquilizers ushered in the age of psychiatric medication.
Haloperidol and .
Haloperidol is an older antipsychotic used in the treatment of schizophrenia and acute psychotic states and delirium.
Haloperidol is sold under the tradenames Aloperidin, Bioperidolo, Brotopon, Dozic, Duraperidol ( Germany ), Einalon S, Eukystol, Haldol ( common tradename in the US and UK ), Halosten, Keselan, Linton, Peluces, Serenace, Serenase, and Sigaperidol.
Haloperidol was approved by the U. S. Food and Drug Administration ( FDA ) on April 12, 1967 ; it was later marketed in the U. S. and other countries under the brand name Haldol by McNeil Laboratories.
Haloperidol is a typical butyrophenone type antipsychotic that exhibits high affinity dopamine D2 receptor antagonism and slow receptor dissociation kinetics.
Los Angeles police stated that his death appeared to be an accidental overdose and that four bottles containing Valium, Vicodin, Soma ( a muscle relaxant ) and Haloperidol ( an anti-psychotic ) were retrieved, later confirmed as prescribed by a specialist, but that no illegal drugs were found at the scene.
Haloperidol, and some other antipsychotics, have been shown to increase the activity of the D < sub > 2 </ sub > receptor when used over long periods of time.
Haloperidol induced activity up to 98 % higher than baseline in as many as two weeks, but yielded significant dyskinesia side effects.
Haloperidol completely reversed the anxiolytic effects, and mecamylamine and ketanserin nearly completely reversed the effects.
Another of Blair's documentaries on medical / social issues, made for ITV on the misuse of the drug Haloperidol in prisons and police stations, has been cited as a good example of how to approach complex medical issues in popular television.
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