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Folding and simulations
Under a non-GPL license, GROMACS is widely used in the Folding @ home distributed computing project for simulations of protein folding, where it is the project's most popular calculation cores.
Through a process known as adaptive sampling, these conformations are used by Folding @ home as starting points for a set of simulations trajectories.
Between 2000 and 2010, the length of the proteins Folding @ home has studied have increased by a factor of four, while its timescales for protein folding simulations have increased by six orders of magnitude.
In 2002, Folding @ home used Markov state models to complete approximately a million CPU days of simulations over the span of several months, and in 2011, MSMs parallelized another simulation that required an aggregate 10 million CPU hours of computation.
The simulations run on Folding @ home are used in conjunction with laboratory experiments, but researchers can use it to study how folding in vitro differs from folding in native cellular environments.
For example, in 2011 Folding @ home continued simulations of folding inside a ribosomal exit tunnel, to help scientists better understand how natural confinement and crowding might influence the folding process.
In 2011 they released the open-source Copernicus software, which is based on Folding @ home's MSM and other parallelization techniques and aims to significantly improve the efficiency and scaling of molecular simulations on large computer clusters or supercomputers.
In 2011, Folding @ home completed simulations of several mutations of Aβ that appear to stabilize the aggregate formation, which could aid in the development of therapeutic drug approaches to the disease as well as greatly assisting with experimental NMR spectroscopy studies of the oligomers.
Later that year, Folding @ home began simulations of various Aβ fragments in order to determine how various natural enzymes affect the structure and folding of.
In 2011, Folding @ home began simulations of the dynamics of the small knottin protein EETI, which can identify carcinomas in imaging scans by binding to surface receptors of cancer cells.
In 2005, Folding @ home tested a new quantum mechanical technique that improved upon previous simulations methods, and which may be useful for future computational studies of collagen.
Using Folding @ home for detailed simulations of vesicle fusion, in 2007 the Pande lab introduced a new technique for measuring fusion intermediate topology.
In 2011 Folding @ home began simulations of the dynamics of the enzyme RNase H, a key component of HIV, in the hopes of designing drugs to deactivate it.

Folding and detail
In 2008 Folding @ home simulated the dynamics ofin atomic detail over timescales of the order of tens of seconds.

Folding and 2006
Since its creation in 2006, the Common Reading Experience has examined books including Folding Paper Cranes: An Atomic Memoir ; Mountains beyond Mountains: The Quest of Dr. Paul Farmer, A Man Who Would Cure the World ; Enrique's Journey: The Story of a Boy's Dangerous Odyssey to Reunite with his Mother ; Outcasts United: An American Town, a Refugee Team, and One Woman's Quest to Make a Difference ; and The Heart & the Fist: The education of a humanitarian, the making of a Navy seal.
In 2006 scientists applied Markov state models and the Folding @ home network to gain detailed mechanistic insights into the fusion process.
Swan ( 2006 ) proposed an algorithm based on Matrix-analytic methods ( Folding algorithm for ruin problems ) which

Folding and 000
Although limited in functionality and scope, it increased participation in Folding @ home from 10, 000 up to about 30, 000 active CPUs.
Although it was limited in functionality and scope, it increased Folding @ home's participation from 10, 000 up to about 30, 000 active CPUs.

Folding and ;
The processes of protein folding and binding can be simulated using such technique as molecular mechanics, in particular, molecular dynamics and Monte Carlo, which increasingly take advantage of parallel and distributed computing ( Folding @ home project ; molecular modeling on GPU ).
* Folding User Interfaces – A mobile phone design concept based on a tetraflexagon ; Folding the design gives access to different user interfaces.
# Folding fans ( Chinese:, zhě shàn ; Japanese:, sensu, can be freely opened ): silk folding fans, paper folding fans, sandalwood fans, etc.
After the funeral, the three girls leave school and the two youngest become apprentices: Martha to Mrs Fairfax, a witch living in Upper Folding, Lettie at Cesari's, a well-known bakery ; 2 weeks later they switch.
Each approach has its own particular benefits and drawbacks ; all work well in practice, and some companies, such as Long Haul Folding Kayaks, offer both materials.
Folding kayaks were used from 1949 to 1963 ; and in the early 1960s, boats were made of fiberglass, and nylon.
; Slings: Folding, portable temporary boat holders.
; Folding @ Custom PC: Custom PC encourages readers to use their idle computers for the purpose of scientific research-Folding @ home is a program created and run by Stanford University that uses spare processor cycles to simulate protein folding for disease research.

Folding and time
Due to its enormous flexibility, which has only briefly been discussed here, coupled with its ability to improve over time, Folding @ home and projects like it are quickly becoming indispensable tools among researchers from a broad variety of disciplines.
There are distributed computing projects which use idle CPU or GPU time of personal computers to solve problems such as protein folding or prediction of protein structure, one prominent example being the Folding @ home project.
* Around this time, Howl also looks for Prince Justin, which is how he gets to meet Lettie in Upper Folding.
After spending time in the bathroom, Howl goes out on the hills again ( he goes to Upper Folding to court Lettie ).
Then he goes to Upper Folding ( for the last time ) to ask Lettie more questions about Sophie, soon followed by Sophie and Michael in seven-league boots.
Folding @ home's participation over time.
In addition to reporting active processors, Folding @ home also determines its computing performance as measured in FLOPS based on the actual execution time of its calculations.
During this time, Dwayne pretended to join the Folding Circle in order to infiltrate them, but he neglected to tell the Warriors this.

Folding and =
| rockets = 24 × 2. 75 in ( 70 mm ) FFAR ( Folding Fin Aerial Rocket ) unguided rockets in missile bay doors

Folding and @
* Folding @ Home ( Stanford University )
Central servers are typically used for listing potential peers ( Tor ), coordinating their activities ( Folding @ home ), and searching ( Napster, eMule ).
Stanford University's Folding @ home project is a distributed computing research effort which uses its approximately 5 petaFLOPS (~ 10 x86 petaFLOPS ) of computing power to attempt to model the tertiary ( and quaternary ) structures of proteins, as well as other aspects of how and why proteins fold into the inordinately complex and varied shapes they take.
Folding @ home allows for the modelling of disease states that are not as easily induced, without the need for test animals.
To date, over 78 scientific papers have been published on discoveries that relied on Folding @ home.
* Folding @ Home
These computers had the Folding @ home program installed, a large-scale distributed computing effort coordinated by Vijay Pande at Stanford University.
To predict protein structure de novo for larger proteins will require better algorithms and larger computational resources like those afforded by either powerful supercomputers ( such as Blue Gene or MDGRAPE-3 ) or distributed computing ( such as Folding @ home, the Human Proteome Folding Project and Rosetta @ Home ).
Several distributed computing projects concerning protein structure prediction have also been implemented, such as the Folding @ home, Rosetta @ home, Human Proteome Folding Project, Predictor @ home, and TANPAKU.
* Points Per Day is a mechanism for measuring work done in the Folding @ home distributed computing project
** Folding @ home, a powerful distributed-computing project for simulating protein folding

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