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Genome and sequence
The Human Genome Project is an initiative of the U. S. Department of Energy (" DOE ") and the National Institutes of Health (" NIH ") that aims to generate a high-quality reference sequence for the entire human genome and identify all the human genes.
The Human Genome Project was organized to map and to sequence the human genome.
It has a small genome size (~ 110Mb ) and its sequence was released by the Joint Genome Institute in early 2008.
The international Potato Genome Sequencing Consortium announced in 2009 that they had achieved a draft sequence of the potato genome.
The sequence of the human reference assembly can be explored using the UCSC Genome Browser or Ensembl.
* KoreaGenome. org: The first Korean Genome published and the sequence is available freely.
It was the sequence of information in a single human's DNA ( that of Dr Craig Venter ) which was the primary initial object of the Human Genome Project.
Among its many recent initiatives, The Genome Center at Washington University ( directed by Richard K. Wilson ) played a leadership role in the Human Genome Project, having contributed 25 % of the finished sequence.
Washington University and its Medical School play a large part in the Human Genome Project, where it contributes approximately 25 % of the finished sequence.
BACs are often used to sequence the genome of organisms in genome projects, for example the Human Genome Project.
In 2004, the U. S .' s National Human Genome Research Institute announced plans to sequence the genome of the domestic guinea pig.
* Radio Free Genome created a musical score from a sequence of alcohol dehydrogenase.
* Prepared Statement of Craig Venter of Celera Venter discusses Celera's progress in deciphering the human genome sequence and its relationship to healthcare and to the federally funded Human Genome Project.
On April 12, 2003, scientists working at the Michael Smith Genome Sciences Centre in Vancouver, British Columbia finished mapping the genetic sequence of a coronavirus believed to be linked to SARS.
Hood was also one of the first advocates of and is a key player in the Human Genome Project -- the quest to decipher the sequence of the human DNA.
* Human Genome Project, is an international scientific research project with a primary goal of determining the sequence of chemical base pairs which make up DNA
Massive amounts of protein sequence data are produced by modern large-scale DNA sequencing efforts such as the Human Genome Project.
Genome projects are scientific endeavours that ultimately aim to determine the complete genome sequence of an organism ( be it an animal, a plant, a fungus, a bacterium, an archaean, a protist or a virus ) and to annotate protein-coding genes and other important genome-encoded features.
With the completion of genome sequencing projects such as the Human Genome Project, modern positional cloning can use ready-made contigs from the genome sequence databases directly.
Its Center for Genome Research was active in the Human Genome Project, and reportedly contributed one-third of the human genome sequence announced in June 2000.
The Chlre3 draft of the Chlamydomonas nuclear genome sequence prepared by Joint Genome Institute of the U. S. Dept of Energy comprises 1557 scaffolds totaling 120 Mb.
There were two main groups attempting to sequence the human genome: the first was the Human Genome Project ( HGP ), the publicly funded effort that intended to publish the information it obtained so the public could use it freely and without restrictions.

Genome and analysis
The term has also been used to describe the analysis of the genetic code information encoded in DNA-see the Human Genome Project article for more on this.
Fortunately, the results of the Human Genome Project have largely replaced the need for RFLP mapping, and the identification of many single-nucleotide polymorphisms ( SNPs ) in that project ( as well as the direct identification of many disease genes and mutations ) has replaced the need for RFLP disease linkage analysis ( see SNP genotyping ).
After a previous initial analysis by the National Human Genome Research Institute confirmed that the bonobo genome is about 0. 4 % divergent from the chimpanzee genome.
According to an analysis of the 1000 Genome Project's sample of Japanese from the Tokyo metropolitan area, the mtDNA haplogroups found among modern Japanese include D ( 42 / 118
* Genome analysis of Botrytis cinerea
* Integrated Microbial Genomes System, a framework for comparative analysis of the genomes sequenced by the Joint Genome Institute
Work reported in the journal Genome Biology in 2005 reports refinement of computational detection methods for identification of protein prenylation motifs and establishment of an on-line analysis facility entitled " PrePS ".
* Nagaharu U. " Genome analysis in Brassica with special reference to the experimental formation of B. napus and peculiar mode of fertilization.
& Banks M .; " Genome sequence analysis of 10 Dutch porcine circovirus type 2 ( PCV-2 ) isolates from a PMWS case-control study.

Genome and Phytophthora
* Phytophthora infestans Mitochondrial Genome Project

sequence and analysis
DNA sequence analysis indicated that Liliales should be divided into at least Liliales, Asparagales and Dioscoreales.
The order is clearly circumscribed on the basis of DNA sequence analysis, but is difficult to define morphologically, since its members are structurally diverse.
* Lexical analysisthe process of processing an input sequence of characters and producing as output a sequence of symbols
* Time-series analysis – methods that attempt to understand a sequence of data points spaced apart at uniform time intervals
* Biological sequence analysis
Another aspect of bioinformatics in sequence analysis is annotation.
The expression of many genes can be determined by measuring mRNA levels with multiple techniques including microarrays, expressed cDNA sequence tag ( EST ) sequencing, serial analysis of gene expression ( SAGE ) tag sequencing, massively parallel signature sequencing ( MPSS ), RNA-Seq, also known as " Whole Transcriptome Shotgun Sequencing " ( WTSS ), or various applications of multiplexed in-situ hybridization.
For example, promoter analysis involves the identification and study of sequence motifs in the DNA surrounding the coding region of a gene.
Bioinformatics is very much involved in making sense of protein microarray and HT MS data ; the former approach faces similar problems as with microarrays targeted at mRNA, the latter involves the problem of matching large amounts of mass data against predicted masses from protein sequence databases, and the complicated statistical analysis of samples where multiple, but incomplete peptides from each protein are detected.
In mathematical analysis, a metric space M is called complete ( or a Cauchy space ) if every Cauchy sequence of points in M has a limit that is also in M or, alternatively, if every Cauchy sequence in M converges in M.
# no universal sequence of stages is apparent – analysis, design and implementation are contemporary and inextricably linked
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of Sequential analysis, a field that was pioneered by Abraham Wald in the context of sequential tests of statistical hypotheses.
Several decades of SETI analysis have not revealed any main sequence stars with unusually bright or meaningfully repetitive radio emissions, although there have been several candidate signals.
The exact size of the GPCR superfamily is unknown but nearly 800 different human genes ( or ≈ 4 % of the entire protein-coding genome ) have been predicted from genome sequence analysis.
( 2006 ) conducted a molecular phylogenetic analysis of 12 of the above 17 species using DNA sequence from three genes: 12S rRNA, cytochrome b, and von Willebrand factor.
However, different types of introns were identified through the examination of intron structure by DNA sequence analysis, together with genetic and biochemical analysis of RNA splicing reactions.
They seem to have radiated in the Gelasian ( Late Pliocene, roughly 2. 5-2 mya, probably starting in tropical East Africa, as indicated by mtDNA cytochrome b sequence data analysis and considerations of biogeography.
This new database provides sharing of information between members of the science community that was not previously seen in northern blotting as it was in sequence analysis, genome determination, protein structure, etc.
Clinical testing of the PKD1 and PKD2 genes by direct sequence analysis is now available, with a detection rate for disease-causing mutations of 50-70 %.
His Los Alamos colleague, Walter Goad, has described their impact on sequence analysis.
This hypothesis was supported by a recent analysis of the Trichoplax adhaerens mitochondrial genome in comparison to those of other animals, The hypothesis was, however, rejected in a statistical analysis of the Trichoplax adhaerens whole genome sequence in comparison to the whole genome sequences of six other animals and two related non-animal species, but only at the p = 0. 07 level, which indicates a marginal level of statistical significance.

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