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* Nucleic acid thermodynamics, includes the annealing of DNA or RNA pairing by hydrogen bonds to a complementary sequence, forming a double-stranded polynucleotide
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Nucleic and acid
Nucleic acid, so called because of its prevalence in cellular nuclei, is the generic name of the family of biopolymers.
Nucleic acid amplification tests ( NAAT ), such as polymerase chain reaction ( PCR ), transcription mediated amplification ( TMA ), and the DNA strand displacement amplification ( SDA ) now are the mainstays.
Nucleic acid molecules are separated by applying an electric field to move the negatively charged molecules through an agarose matrix.
Nucleic acids were named for their initial discovery within the nucleus, and for the presence of phosphate groups ( related to phosphoric acid ).
Nucleic acid types differ in the structure of the sugar in their nucleotides-DNA contains 2 '- deoxyribose while RNA contains ribose ( where the only difference is the presence of a hydroxyl group ).
Nucleic acid vaccines are still experimental, and have been applied to a number of viral, bacterial and parasitic models of disease, as well as to several tumour models.
Nucleic and thermodynamics
Nucleic and DNA
* 1953 – Francis Crick and James D. Watson publish " Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid " describing the double helix structure of DNA.
Nucleic acids are the molecules that make up DNA, an extremely important substance that all cellular organisms use to store their genetic information.
Confirmation and clarity came a year later in 1953, when James D. Watson and Francis Crick correctly hypothesized, in their journal article " Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid ", the double helix structure of DNA, and suggested the copying mechanism by which DNA functions as hereditary material.
Nucleic acids are also generated within the laboratory, through the use of enzymes ( DNA and RNA polymerases ) and by solid-phase chemical synthesis.
Nucleic receptors have DNA-binding domains containing zinc fingers and a ligand-binding domain ; the zinc fingers stabilize DNA binding by holding its phosphate backbone.
* April 25 – Francis Crick and James D. Watson publish " Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid ", their description of the double helix structure of DNA.
Nucleic acid electrophoresis is an analytical technique used to separate DNA or RNA fragments by size and reactivity.
Biological Implications of the Mechanism of Action of Human DNA ( Cytosine-5 ) Methyltransferase Progress in Nucleic Acids Research and Molecular Biology 49: 65 – 111.
* April 25-Francis Crick and James D. Watson of the University of Cambridge's Cavendish Laboratory publish " Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid " in the British journal Nature ( first announced on February 28 at a Solvay Conference ), often ranked as one of the most dramatic results in biology during the 20th century because of the structural beauty and functional logic of the DNA double helix.
Their article, Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid, is celebrated for its treatment of the B form of DNA ( B-DNA ), and as the source of Watson-Crick base pairing of nucleotides.
Nucleic and RNA
Nucleic acids were first discovered in 1868 by Friedrich Miescher and by 1939 RNA had been implicated in protein synthesis.
Nucleic acids ( precisely the single, free nucleotides, not those bound in a DNA / RNA strand ) has an extremely short lifetime due to a fast internal conversion.
0.156 seconds.