At the present time we do not know by what biochemical mechanism TSH acts on the thyroid, but for bio-assay of the hormone there are a number of properties by which its activity may be estimated, including release of iodine from the thyroid, increase in thyroid weight, increase in mean height of the follicular cells and increase in the thyroidal uptake of Af.

* A biochemical mechanism for inactivation is present.

The biochemical mechanism that determines product length is not fully characterized.

Their classification by mechanism of action ( MOA ) indicates the first enzyme, protein, or biochemical step affected in the plant following application.

The biochemical mechanism for this disease in the Jacob sheep is virtually identical to that in humans, wherein diminished activity of hexosaminidase A results in increased concentrations of GM2 ganglioside in the affected animal.

Each step in this pathway, as in many biochemical pathways, not only passes information along to stimulate the next region but also receives feedback from messengers produced later in the pathway to either enhance or suppress earlier steps in the pathway – this is one way a biochemical pathway can regulate itself, via a feedback mechanism.

Much research, both biochemical and structural, has been performed to obtain clues about the mechanism of reuptake.

Additionally, biochemical mechanisms have become more widely used in neurotoxin testing, such that compounds can be screened for sufficiency to induce cell mechanism interference, like the inhibition of acetylcholinesterase capacity of organophosphates ( includes DDT and sarin gas ).

The biochemical mechanism of action of general anaesthetics is not yet well understood.

Agonists were thought to turn " on " a single cellular response by binding to the receptor, thus initiating a biochemical mechanism for change within a cell.

Our understanding of the mechanism of drug-induced receptor activation and receptor theory and the biochemical definition of a receptor antagonist continues to evolve.

Such breaks are not considered DNA damage because they are a natural intermediate in the topoisomerase biochemical mechanism and are immediately repaired by the enzymes that created them.

With this structure and other biochemical experiments, MacKinnon and colleagues were able to explain the exact mechanism by which potassium channel selectivity occurs.

At the time, the biochemical mechanism of ATP synthesis by oxidative phosphorylation was unknown.

A circadian clock, or circadian oscillator, is a biochemical mechanism that oscillates with a period of 24 hours and is coordinated with the day-night cycle.

The detailed biochemical mechanism that leads to BBS is still unclear.

In his eclectic lab, developmental work on the frog coexists with biochemical work on mechanism of ubiquitination, cytoskeleton assembly or signal transduction.

The availability of genome sequences provides a new opportunity for scientists to learn more about the evolution and biochemical capacity of these parasite.

This is important in the biosynthesis of amino acids, as for many of the pathways, intermediates from other biochemical pathways are converted to the α-keto acid skeleton, and then an amino group is added, often via transamination.

The electrons pass into the cells and are used in biochemical processes to produce energy for the bacteria while reducing oxygen to water.

In simpler term, Biotechnology is the research and development in the laboratory that involves bioinformatics for exploration, extraction, exploitation and production from any living organisms and any source of biomass by means of biochemical engineering where high value-added products could be planned ( reproduced by Biosynthesis, for example ), fore-casted, formulated, developed, manufactured and marketed for the purpose of sustainable operations ( for the return from bottomless initial investment on R & D ) and gaining durable patents rights ( for exclusives rights for sales, and prior to this to receive national and international approval from the results on animal experiment and human experiment, especially on the pharmaceutical branch of biotechnology to prevent any undetected side-effects on safety concerns by using the products ), for more about the biotechnology industry, see.

At about the same time the development of effective polymerase chain reaction techniques allowed the application of cladistic methods to biochemical and molecular genetic traits of organisms as well as to anatomical ones, vastly expanding the amount of data available for phylogenetics.

Advancements in biochemical engineering in the 1940s, for example, found application in the pharmaceutical industry, and allowed for the mass production of various antibiotics, including penicillin and streptomycin.

Many Earth plants and animals undergo major biochemical changes during their life cycles as a response to changing environmental conditions, for example, by having a spore or hibernation state that can be sustained for years or even millennia between more active life stages.

In 1907, he received the Nobel Prize in Chemistry " for his biochemical research and his discovery of cell-free fermentation ".

It should be noted that many animal models are poor substitutes for studying carcinogenic effects in humans because the physiology of rabbits, mice and non-human primates can be very different from humans in the relevant biochemical pathways.

Regulatory GTPases, also called the GTPase superfamily, are GTPases used for regulation of other biochemical processes.

Although Behe acknowledged that the evolution of the larger anatomical features of the eye have been well-explained, he claimed that the complexity of the minute biochemical reactions required at a molecular level for light sensitivity still defies explanation.

Behe maintains that the complexity of light sensitivity at the molecular level and the minute biochemical reactions required for those first “ simple patches of photoreceptor ” still defies explanation.

In this novella, a young lawyer suspects he may be an alien because of certain physical and biochemical abnormalities but discovers that he is a commercial human embryonic cell line, sold for research and illegally grown to maturity.

testing of air / water samples for biochemical toxins and other dangerous

are adequate for many well-defined and simple biochemical applications, and for certain tasks such

Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.

Having shown that enzymes could function outside a living cell, the next step was to determine their biochemical nature.

The early 1960s revealed a revolutionary model by Julius Axelrod describing nerve signals and synaptic transmission, which was followed by a drastic increase of biochemical brain research into the effects of psychotropic agents on brain chemistry.

In the 1960s and early 1970s, when the biochemical basis of Tay – Sachs disease was first becoming known, no mutations had been sequenced directly for genetic diseases.

Mitochondrial DNA was discovered in the 1960s by Margit M. K. Nass and Sylvan Nass by electron microscopy as DNase-sensitive thread inside mitochondria, and by Ellen Haslbrunner, Hans Tuppy and Gottfried Schatz by biochemical assays on highly purified mitochondrial fractions.

Scientists around this time began discovering many biochemical compounds that play a significant role in biological processes and pepsin was one of them.

Until the improvements in biochemical analysis methods towards the end of the 20th century, very little was known about the relationships between the smaller carnivorous marsupials: it is only in recent years that it has been possible to discover that the Planigalinae are a distinct group within the Dasyuromorphia.

Later fossil finds indicated that Ramapithecus was more closely related to the orangutan, and new biochemical evidence indicated that the last common ancestor of humans and other hominins occurred between 5 and 10 million years ago, and probably in the lower end of that range.

This mixture was then operated upon algorithmically using biochemical techniques to winnow out the ' incorrect ' strands, leaving behind only those strands that ' satisfied ' the problem.

Kutcher enrolled at the University of Iowa in August 1996, where his planned major was biochemical engineering, motivated by the desire to find a cure for his brother's heart ailment.

Huntingdon Life Sciences was originally founded in the UK in 1951 as Nutrition Research Co. Ltd., a commercial organisation that initially focused on nutrition, veterinary, and biochemical research.

As a result, the final effluent was a deep red colour, and were a major factor in the poor biochemical oxygen demand ratings for the river.

It was while seeking an inorganic analog of the biochemical citric acid cycle that Belousov chanced to discover an oscillating chemical reaction.

It was pointed out that Pokhlyobkin used Mendeleyev's data in a speculative way to ascribe to solution of spirit and water the eminent " biochemical and physiological properties ".

The biochemical basis for the disease was elucidated in 1965.

The biochemical definition of a receptor antagonist was introduced by Ariens and Stephenson in the 1950s.

Further to this, there was a suggestion that the microtubules could be pumped into a coherent state by biochemical energy.

George Wells Beadle ( October 22, 1903 – June 9, 1989 ) was an American scientist in the field of genetics, and Nobel Prize in Physiology or Medicine Nobel laureate who with Edward Lawrie Tatum discovered the role of genes in regulating biochemical events within cells.

The exact biochemical activity of transglutaminases was discovered in blood coagulation protein factor XIII in 1968.

AST was defined as a biochemical marker for the diagnosis of acute myocardial infarction in 1954.

Michael Lesch was a medical student at Johns Hopkins University and Bill Nyhan, a pediatrician and biochemical geneticist, was his mentor, when the two identified LNS and its associated hyperuricemia in two affected brothers, ages 4 and 8.

In 1955 he was invited by Professor Michael Swann to set up a biochemical research unit, called the Chemical Biology Unit, in the Department of Zoology, Edinburgh University, where he was appointed to a Senior Lectureship in 1961, to a Readership in 1962, although ill health led to his resignation in 1963.