Illicit diversion has been a problem, but to the many proponents of the utilization of morphine for OST, the benefits far outweigh the costs, taking into account the much higher percentage of addicts who are " held " or, from another perspective, satisfied by this treatment option, as opposed to methadone and buprenorphine treated addicts, who are more likely to forgo their treatment and revert to using heroin etc., in many cases by selling their methadone or buprenorphine prescriptions to afford their opiate of choice.

Illicit diversion has been a problem, but to the many proponents of the utilization of morphine for OST, the benefits far outweigh the costs, taking into account the much higher percentage of addicts who are " held " or, from another perspective, satisfied by this treatment option, as opposed to methadone and buprenorphine treated addicts, who are more likely to forgo their treatment and revert to using heroin etc., in many cases by selling their methadone or buprenorphine prescriptions to afford their opiate of choice.

The risk of further episodes of diabetic hypoglycemia can often ( but not always ) be reduced by lowering the dose of insulin or other medications, or by more meticulous attention to blood sugar balance during unusual hours, higher levels of exercise, or decreasing alcohol intake.

Low dose applications such as disinfestation of fruit range between US $ 0. 01 / lbs and US $ 0. 08 / lbs while higher dose applications can cost as much as US $ 0. 20 / lbs.

However, this also means that LD < sub > 50 </ sub > is not the lethal dose for all subjects ; some may be killed by much less, while others survive doses far higher than the LD < sub > 50 </ sub >.

If used as emergency contraception, a low dose of mifepristone is slightly less effective than higher doses, but has fewer side effects.

In practice much lower thresholds were maintained even though the optimal dose varies greatly between patients, often quite higher than this and with no inherent threshold in the possible dose, as the toxic dose for patients with very high tolerance can exceed this tenfold or more.

( Other sources give a much higher oral LD < sub > Lo </ sub > ( lowest published lethal dose ) of 600 mg / kg.

Guidelines differ as to which dose to use when blood sugar levels start falling ; some recommend reducing the dose of insulin once glucose falls below 16. 6 mmol / l ( 300 mg / dl ) but other recommend infusing glucose in addition to saline to allow for ongoing infusion of higher doses of insulin.

In the absence of H. pylori, long-term higher dose PPIs are often used.

The dose, unless further modified, could now be higher than desired, potentially causing increased drug-related toxicity.

Clove oil can be used to anesthetize fish, and prolonged exposure to higher doses ( the recommended dose is 400 mg / l ) is considered a humane means of euthanasia.

Some clinicians may prefer to administer a higher dose ( typically 18 mg ), rather than repeat a dose that apparently had no effect.

In a flexible dosing study, it appeared that a higher dose range was needed for adequate response.

In many occupational scenarios, the hourly dose rate might fluctuate to levels thousands of times higher for a brief period of time, without infringing on the annual limits.

The higher the dose, the greater the risk to the heart.

Women who have already had a baby with spina bifida or other type of neural tube defect, or are taking anticonvulsant medication should take a higher dose of 4 – 5 mg / day.

* Dose response relationshipsThere exists a quantitative correlation between the magnitude of embryopathic effects and the dose of the teratogenic agent, such that the higher the dose, the more severe the teratogenic effect.

Lorazepam's effects are dose-dependent, meaning the higher the dose, the stronger the effects ( and side effects ) will be.

Increasing the dose may overcome tolerance, but tolerance may then develop to the higher dose and adverse effects may persist and worsen.

In medicine the frequencies are much higher, transducers and the sonar beams themselves are much smaller, and different scanning techniques may be used, but the principles involved are the same as in sonar.

`` Increased boundary maintenance may be achieved, for example, by assigning a higher primacy or evaluation to activities characteristic of the external pattern.

This exception may be connected with Hoijer's use of a much higher percentage of verbs: 22% of his total list as against 3.5% in mine.

These minimum costs may come to $1 per month, more or less, for residential and small commercial customers, although they are substantially higher for large industrial users, who require more costly connections and metering devices.

`` Costs may seem high, but they used to be even higher '', says Dr. Brodie.

Though this may or may not be good biology, it does aptly illustrate the strength and the weakness of American Catholic higher education.

The arithmetic mean may be misinterpreted as the median to imply that most values are higher or lower than is actually the case.

For example, a criminal defendant may be convicted in state court, and lose on " direct appeal " to higher state appellate courts, and if unsuccessful, mount a " collateral " action such as filing for a writ of habeas corpus in the federal courts.

In some cases, an appellant may successfully argue that the law under which the lower decision was rendered was unconstitutional or otherwise invalid, or may convince the higher court to order a new trial on the basis that evidence earlier sought was concealed or only recently discovered.

This may, therefore, explain decreased coordination at higher movement velocities and accelerations.

Weight for weight, screw anchors have a higher holding than other permanent designs, and so can be cheap and relatively easily installed, although may not be ideal in extremely soft mud.

152-153 .</ ref > The moon and sun are likewise considered to be flat and floating on streams of air, and when the sun sets it does not pass under the earth but is merely obscured by higher parts of the earth as it circles around and becomes more distant ; the motion of the sun and the other celestial bodies around the earth is likened by Anaximenes to the way that a cap may be turned around the head .< ref > Fairbanks, Arthur.

Apart from the lowlands and the Atlas mountain range, the continent may be divided into two regions of higher and lower plateaus, the dividing line ( somewhat concave to the north-west ) running from the middle of the Red Sea to about 6 deg.

Red wine may have a higher alcohol content ( on average 12. 5 %, sometimes up to 16 %).

When a core electron is removed, leaving a vacancy, an electron from a higher energy level may fall into the vacancy, resulting in a release of energy.

General support units may be grouped into artillery formations for example, brigades even divisions, or multi-battalion regiments, and usually under command of division, corps or higher HQs.

The mean and maximal doses used for olanzapine were considerably higher than standard practice, and this has been postulated as a biasing factor that may explain olanzapine's superior efficacy over the other atypical antipsychotics studied, where doses were more in line with clinically relevant practices.

Traders may, for example, find that the price of wheat is lower in agricultural regions than in cities, purchase the good, and transport it to another region to sell at a higher price.

Keys plated with other metals are not affected by the settlement, and may continue to use brass alloys with higher percentage of lead content.

However the carcass value of double-muscled animals may be enhanced due to increased dressing yield, lean carcass content, and upgrading of some cuts leading to a higher proportion of higher valued cuts.

Bromine has no known essential role in human or mammalian health, but inorganic bromine and organobromine compounds do occur naturally, and some may be of use to higher organisms in dealing with parasites.

A die may not be used to bear off checkers from a lower-numbered point unless there are no checkers on any higher points.