After binding dsRNA, this receptor activates the transcription factors IRF3 and NF-κB, which are important for initiating synthesis of many inflammatory proteins.

After the effects of the drug wear off, one might feel depressed because of the decreased probability of the neurotransmitter binding to a receptor.

After chronic use, neurons adapt to the change in biochemistry, resulting in a change in pre-and postsynaptic receptor density and second messenger function.

After the estrogen receptor has bound its ligand, estradiol can enter the nucleus of the target cell, and regulate gene transcription, which leads to formation of messenger RNA.

After 15 days of continual dosing, both androgen receptor levels and serum testosterone levels were significantly reduced.

After a short period of chronic treatment, however, the H < sub > 1 </ sub > receptor tends to sensitize and the antihistamine effects become more tolerable.

After a hormone binds to the corresponding receptor, the newly formed receptor-ligand complex translocates itself into the cell nucleus, where it binds to glucocorticoid response elements ( GRE ) in the promoter region of the target genes resulting in the regulation of gene expression.

After a hormone binds to the corresponding receptor, the newly formed receptor-ligand complex translocates itself into the cell nucleus, where it binds to many hormone response elements ( HREs ) in the promoter region of the target genes in the DNA.

After the receptor is engaged, multiple intracellular signal transduction pathways are activated.

After receptor binding, rabies virus enters its host cells through the endosomal transport pathway.

After binding to the receptor, the virus enters the cell where it uncoats.

After progesterone binds to the receptor, restructuring with dimerization follows and the complex enters the nucleus and binds to DNA.

After their death, Postumus claimed the consulship for himself and one of his associates, Honoratianus but, according to D. S.

Lowell and his partners built America's second cotton-to-cloth textile mill at Waltham, Massachusetts, second to the Beverly Cotton Manufactory After his death in 1817, his associates built America's first planned factory town, which they named after him.

After the attacks, the identification of Mihdhar was one of the first links suggesting that Bin Laden had played a role in their organization, since Mihdhar had been seen at the Malaysian conference speaking to Bin Laden's associates.

After Zhdanov died suddenly in August 1948, Beria and Malenkov consolidated their power by a purge of Zhdanov's associates known as the " Leningrad Affair ".

After the Reagan camp lost the Iowa caucus and fell behind in New Hampshire polls, Nancy organized a second meeting and decided it was time to fire Sears and his associates ; she gave Sears a copy of the press release announcing his dismissal.

After Jianwen arrested many of Zhu Di's associates, Zhu Di plotted a rebellion, a rebellion that sparked a three-year civil war.

After the murder of Sergei Kirov on 1 December 1934 led to Stalin's Great Purges, Grigory Zinoviev, Kamenev and their closest associates were once again expelled from the Communist Party and arrested in December 1934.

After the murder of Sergei Kirov on December 1, 1934, which served as one of the triggers to Great Purge of the Communist Party, Zinoviev, Kamenev, and their closest associates were once again expelled from the party and arrested in December 1934.

After the poet Opitz died, pastor Nigrinus with two of his associates edited the Opitz poems published by Huenefeld.

After Barrow was released from prison in February 1932, he and Ralph Fults assembled a rotating core group of associates and began a series of small robberies, primarily of stores and gas stations ; their goal was to collect enough money and firepower to launch a raid of liberation against Eastham prison.

After the Senior Partners revert time to before the Fall, Spike begins a loosely-affiliated relationship with the reformed Angel Investigations company, collaborating with Angel and his associates while maintaining independence.

After establishing himself in the presidency, in 1936 Cárdenas had Calles and dozens of his corrupt associates arrested or deported to the United States.

After Ushas appear Aditi, the Primal Sun, the God of Light, first as Savitr, who represents the Divine grace essential for all spiritual success, and then as Mitra, who as the Divine love is considered as a friend of the illumined mind ( Indra ) and his associates ( the other gods ).

After the incident at the cemetery, Wilkes and seven associates were arrested and taken before Justice Donahue.

After approaches to the government to reconsider the acquisition bill failed, Casley and his associates resorted to International Law, which they felt allowed them to secede and declare their independence from the Commonwealth of Australia.

After several attempts to re-establish the airline's business, the company was sold on January 13, 2009 to an industry group owned by Mr. Tomas Romero and associates.

After being confronted by his worried parents and receiving a threatening visit from Mr. Eddy and his associates at the shop, Pete enters Andy's house through a door left unlocked by Alice and, while searching the house, discovers a projector playing a porno film featuring her.

After sharing a prison cell with Boss Vito Genovese following his conviction for heroin trafficking, Gigante became a caporegime, overseeing his own crew of Genovese soldiers and associates that operated out of Greenwich Village.

After spending most of his life in a nomadic existence " up and down the dial ", WKRP settles Johnny down and establishes a relatively stable ensemble of friends and associates for him.

After the inauguration, the Marcos family and their close associates hurriedly rushed to leave the Palace.

After September 1940 the army began to take charge of the Home Guard training in Osterley, and Wintringham and his associates were gradually sidelined.

After all there was absolutely no vocal or verbal provocation from me or from my associates, including Peter Miguel Camejo, to warrant such an outburst.

After he said he received the Golden Plates, Smith began to dictate their translation to his wife Emma Hale Smith and various associates of his, including Martin Harris and, for most of the later translation, Oliver Cowdery.

After Bates died in 1931, his methods of treatment were continued by his widow Emily and other associates, some of whom incorporated exercises and dietary recommendations.

After the war, Penny had wanted Keith at least to visit her home with her.

After that, it requires several minutes of concentrated work, including six separate and deliberate actions by a minimum of three men sitting at three separate stations in a bomber, each with another man beside him to help, for an armed bomb to be released.

After the war began, he long refused to permit emancipation of the slaves by Union action even in the Border States that stayed with the Union.

After luncheon we took advantage of the siesta period to try to get in touch with a few people to whom our dear friend Deppy had written.

After they had paid all his debts and the funeral costs, Ralph and Fred had some fourteen thousand dollars, as I remember, with which to pay the bequests.

After Kahn's death in 1924 Scott wrote: `` May he rest in peace with the eternal gratitude of his adopted country ''.

After declaring, in an article last month in Frontier Magazine, that the Russian testing `` carries with it the possibility of the most tragic consequences of any action in the history of the world '', he gave this estimate of the biologic and genetic consequences if the new Soviet shots totaled 200 megatons:

After she had served the detectives coffee and toast ( they politely declined eggs, uncomfortable about their tenancy ), she settled down with a morning newspaper and began reading the stock market quotations.

After well broken and equipped with 12-oz. shoes on behind, bare-footed in front, she would trot a real storm with the master, Delvin, driving.

-- After 52 rainless days, moisture finally came to Del Mar, resulting in but one workout during the week for most of the horses, and leaving us with less than half our total average rainfall during the season.

After notching it for the keelson, chines and battens, the half-inch plywood transom is secured to it with glue and the same type nails.

After selecting a sheet and inspecting it for flaws ( even the best sometimes has foreign ' nubbins ' on its surface ), I sponge it thoroughly on both sides with clean, cold water.

After five minutes with Blanche, one might welcome the astringency of Grazie, who was a sort of Gwen Cafritz to Francesca's Perle Mesta.

After an unspeakable siege, lasting the better part of two months, it was announced that the studio `` owed '' the government a tax debt in excess of eight million dollars while I, who had always remained aloof from such iniquitous practices as paying taxes on the salary I had earned and the little I legally inherited as Morris' helpless relict, was `` stung '' with a personal bill of such astronomical proportions as to `` wipe out '' all but a fraction of my poor, hard-come-by savings.

After titration of the liberated Af with Af, aliquots of the aqueous and of the organic phase were counted in a solution-type Geiger tube.

After dialysis the sample was centrifuged and the supernatant placed on a Af cm column of EEAE-cellulose equilibrated with starting buffer.

After their work other investigators applied salt-fractionation techniques to the problem, as well as fractionation with organic solvents, such as acetone.

After blotting out most of the saline around the sections, a drop of Af was layered over each of the sections, allowed to react for 30 minutes, and then washed with PBS for 15 - 30 minutes.

After drying the sections under the fan, fixing in acetone, and drying at 37-degrees as in the indirect method, the sections were treated with conjugated Af or Af ( undiluted unless mentioned otherwise ) for 5 - 30 minutes.

After Af and Af were passed through Dowex-2-chloride twice and treated twice with healthy sweet clover tissue powder, nonspecific staining was greatly reduced but a disturbing amount of such staining was still present.

After a conversation with another man, he was able to recount practically everything that had been said but could not describe at all what the other man looked like.

After many years and many interruptions he was able to finish the canopy fresco, and slightly less than half the frieze, beginning with the Liberty group opposite the East door, and ending with William Penn, all but one leg, when a tragic accident ended his career.

After all, the henpecked husband with his shrewish wife is a comic figure of long standing, in literature and on the stage, as Dr. Schillinger points out.