Although MND refers to a specific subset of pathologically similar diseases ; there are numerous other afflictions of motor neurons that are pathologically distinct from MND and have a different clinical course.

Although still actively involved in running his many businesses, Carnegie had become a regular contributor to numerous magazines, most notably the Nineteenth Century, under the editorship of James Knowles, and the influential North American Review, led by editor Lloyd Bryce.

According to Kenneth S. Rogoff, " Although the development of international capital markets was quite limited prior to 1800, we nevertheless catalog the numerous defaults of France, Portugal, Prussia, Spain, and the early Italian city-states.

Although established to target the Irish Republican Army, the Black and Tans became notorious through their numerous attacks on the Irish civilian population.

Although besieged on numerous occasions by various peoples, it was taken only in 1204 by the army of the Fourth Crusade, in 1261 by Michael VIII, and in 1453 by the Ottoman Sultan Mehmed II.

Although there are numerous kinds of disaccharides, a handful of disaccharides are particularly notable.

Although the film was less than successful at the box office in the wake of 9 / 11, it reached cult film status after the DVD release, inspiring numerous websites devoted to unraveling the plot twists and meanings.

Although Dyson has won numerous scientific awards, he has never won a Nobel Prize, which has led Nobel physics laureate Steven Weinberg to state that the Nobel committee has " fleeced " Dyson.

Although numerous classification schemes have been proposed, the superfamily is classically divided into three main classes ( A, B, and C ) with no detectable shared sequence homology between classes.

Although not certain, it has been believed that during a 40 year period of the Third Dynasty, Imhotep influenced and was the ultimate master builder of numerous other projects which have been finished.

Although now focused primarily on spoken word, he has continued as a musician in numerous collaborations.

Although reduced, its range remains large ; given its historical distribution, the jaguar has featured prominently in the mythology of numerous indigenous American cultures, including that of the Maya and Aztec.

Although numerous political references to the " Wizard " appeared early in the 20th century, it was in a scholarly article by Henry Littlefield, an upstate New York high school history teacher, published in 1964 that there appeared the first full-fledged interpretation of the novel as an extended political allegory of the politics and characters of the 1890s.

Although lutes were in widespread use in Europe at least since the 13th century, and documents mention numerous early performers and composers, the earliest surviving music for the instrument dates from the late 15th century.

Although it is a subject of debate whether Teotihuacan was the center of a state empire, its influence throughout Mesoamerica is well documented ; evidence of Teotihuacano presence can be seen at numerous sites in Veracruz and the Maya region.

Although most of the original writings of the founding prophet Mani ( in Persian: مانی, Syriac:, Latin: Manichaeus or Manes ) ( c. AD 216 – 276 ) have been lost, numerous translations and fragmentary texts have survived.

Although spun out of licensed properties, Shang-Chi is a Marvel-owned character and has been firmly established as a part of the Marvel Universe with guest appearances in numerous other titles, such as Marvel Team-Up, Marvel Knights and X-Men.

Although it has never been determined exactly how extensive Shang-Chi's fighting skills are, he has beaten numerous superhuman opponents.

Although Mad was an exclusively freelance publication, it achieved a remarkable stability, with numerous contributors remaining prominent for decades.

Although he never personally commanded troops in the field, he usually wore a general's uniform in public for the rest of his life, as seen in numerous paintings and photographs.

Although Falk appeared in numerous other television roles in the 1960s and 1970s, he is best known as the star of the TV series Columbo, " everyone's favorite rumpled television detective ", writes historian David Fantle.

Although he obtained numerous privileges for his see and Honorius always spoke encouragingly to him, Honorius avoided having to make a decision that might alienate the powerful archbishops of Canterbury.

Although numerous variations of ingredients for different pasta products are known, in Italy the commercial manufacturing and labeling of pasta for sale as a food product within the country is highly regulated. Italian regulations recognise three categories of commercially manufactured dried pasta as well as manufactured fresh and stabilized pasta:

Although largely replaced since the introduction of the compact disc in 1982, record albums still sell in small numbers and are available through numerous sources.

Although Orbison is counted as a rock and roll pioneer, and has been cited by numerous critics as one of the genre's most influential musicians, his style was noted for how it departed from the norm.

Although a somewhat technical subject, it has important political implications as the above discussion of the voting system indicated.

Although it looked like a routine technical snapback to Wall Streeters it was accompanied by some good news.

Although passengers rarely have cause to refer to either document, all travel is subject to the National Rail Conditions of Carriage and all tickets are valid subject to the rules set out in a number of so-called technical manuals, which are centrally produced for the network.

Although mechanisation of the Army was considered as a means of avoiding the heavy casualties and indecisive nature of the offensives during the earlier years of the war, no strategic doctrine was evolved to match technical developments.

Although the term " clitic " can be used descriptively to refer to any element whose grammatical status is somewhere in between a typical word and a typical affix, linguists have proposed various definitions of " clitic " as a technical term.

Although Coppola insisted that this was purely coincidental, for not only was the script for The Conversation completed in the mid-1960s ( before the election of Richard Nixon ) but the spying equipment used in the film was discovered through research and the use of technical advisers and not, as many believed, by revelatory newspaper stories about the Watergate break-in.

Although the war made things much worse for European producers, the technical qualities of American films made them increasingly attractive to audiences everywhere.

Although this should, in theory, be highly effective in counteracting genetic disorders and hereditary diseases, many jurisdictions prohibit this for application in human beings, at least for the present, for a variety of technical and ethical reasons.

Although mining had long been practised in Britain ( see Grimes Graves ), the Romans introduced new technical knowledge and large-scale industrial production to revolutionise the industry.

Although this is not the technical definition of the Hamiltonian in classical mechanics, it is the form it most commonly takes.

Although many techniques are used by vaulters at various skill levels to clear the bar, the generally accepted technical model can be broken down into several phases, listed and described below:

Although the distinction may seem technical to native speakers of many languages, it is quite the reverse among the 250 or so autochthonous Australian languages.

Although there are doctrinal and technical differences between sparring in the two main styles and among the various organizations, the art in general emphasizes kicks thrown from a mobile stance, employing the leg's greater reach and power ( compared to the arm ).

Although usually circular in cross-section, wire can be made in square or flattened rectangular cross-section, either for decorative purposes, or for technical purposes such as high-efficiency voice coils in loudspeakers.

Although telecine machines for 70 mm scanning are uncommon, high-resolution transfers from high-quality full-gauge elements can reveal impressive technical quality.

Although privateering commissions and letters of marque were originally distinct legal concepts, such distinctions became purely technical by the eighteenth century.

Although the term " biotope " is considered to be a technical word with respect to ecology, in recent years the term is more generally used in administratitive and civic activities.

Although commonly misportrayed as buskers, mariachis musicians play extremely technical, structured music or blends such as jarabe.

Although two designs, the Canadair CL-84 Dynavert and the LTV XC-142, were technical successes, neither entered production due to other issues.

Although the TDK-D C180 was produced for a decade ( 1972-82 ), it is very rare, because of several technical flaws.

Although his company PKWARE became a multimillion dollar company, Katz was more noted for his technical expertise than business prowess.

Although many of his escapes relied on technical skills such as lock-picking and contortion, he also performed tricks such as Metamorphosis and the Chinese Water Torture Cell, which are essentially classic stage illusions reliant on cleverly designed props.

Although many assumed the bands were playing live, due to technical issues and the need to ensure performances were controlled, the bands often recorded the performance on the day of shooting prior to taping, and then mimed to this " live " track.

Although " trust " had a technical legal meaning, the word was commonly used to denote big business, especially a large, growing manufacturing conglomerate of the sort that suddenly emerged in great numbers in the 1880s and 1890s.