Although major concerns about benzodiazepine tolerance and withdrawal have been raised, there is no evidence for significant dose escalation in patients using benzodiazepines long-term.

Although the best treatment for comatose patients remains unknown, hospitals usually place comatose patients in an Intensive Care Unit ( ICU ) immediately.

Although prophylaxis is available and is often initiated in patients with large tumors, this is a dangerous side-effect that can lead to death if left untreated.

Although less common, it may also present in patients with a history of chronic alcoholism or other conditions related to decreased liver function.

Although essential tremor is often mild, patients with severe tremor have difficulty performing many of their routine activities of daily living.

Although pain has not been traditionally part of the " textbook " description, many patients report severe muscle pain, especially in the thighs.

Although seizure and myoclonus can be controlled for a long period by using antiepileptic drugs, patients rarely survive beyond one or two decades due to the devastating effects of dementia and ataxia.

Although some of these patients improve following thymectomy, some patients experience severe exacerbations and the highly controversial concept of " therapeutic thymectomy " for patients with thymus hyperplasia is disputed by many experts, and efforts are underway to unequivocally answer this important question.

Although unpleasantness is an essential part of the IASP definition of pain, it is possible to induce a state described as intense pain devoid of unpleasantness in some patients, with morphine injection or psychosurgery.

Although the possibility exists that significant biological effects on humans may be identified in the future, currently most doctors feel that based on available information the benefits to patients outweigh the risks.

Although nitrous oxide, or laughing gas, had been proposed as an anaesthetic as far back as 1799 by Humphry Davy, it wasn't until 1846 when an American Dentist named William Morton started using ether on his patients that anaesthetics became common in the medical profession.

Although the forced quarantine or segregation of patients is unnecessary in places where adequate treatments are available, many leper colonies still remain around the world in countries such as India ( where there are still more than 1, 000 leper colonies ), China, Romania, Egypt, Nepal, Somalia, Liberia, Vietnam, and Japan.

Although applying this technique with consistency is difficult, it can have a positive effect on insomnia in motivated patients.

Although defined as a mononeuritis ( involving only one nerve ), patients diagnosed with Bell ’ s palsy may have " myriad neurological symptoms " including " facial tingling, moderate or severe headache / neck pain, memory problems, balance problems, ipsilateral limb paresthesias, ipsilateral limb weakness, and a sense of clumsiness " that are " unexplained by facial nerve dysfunction ".

Although some investigations have shown that patients may be at higher risk for ectopic pregnancy with advancing age, it is believed that age is a variable which could act as a surrogate for other risk factors.

Although these tests can be very useful in CRPS, thorough informed consent needs to be obtained prior to the procedure, particularly in patients experiencing severe allodynia.

Although this is the main way in which PE is diagnosed, there are current studies that have shown that PCR may be used to identify E. oligarthus and E. vogeli in patients ’ tissues.

Although there is strong evidence that treatment of iron overload can save lives in patients with transfusional iron overload, no clinical study has shown that for asymptomatic carriers of hereditary haemochromatosis treatment with venesection ( phlebotomy ) provides any clinical benefit.

Although specialists recommend individuals who need to wear eyeglasses to have them custom-made according to their own needs, most of the patients prefer buying them at a pharmacy or department store.

Although prostate specific antigen levels may be elevated in these patients because of increased organ volume and inflammation due to urinary tract infections, BPH does not lead to cancer or increase the risk of cancer.

Although only 1 % of AIDS patients contract PML, it usually dissipates on its own in patients with T-cell counts higher than 300-400.

Although he questions the extent and nature of the alleged revival of religion and the alleged increase in conformity, and thinks that `` hedonistic '' present-time orientation does not have the meaning usually attributed to it, he does conclude that Americans increasingly enjoy leisure without guilt, do not stress achievement so much as formerly, are more accepting of group harmony as a goal, more tolerant of diversity and aware of other cultures.

Although the false glamour surrounding bourbon or other whisky commercials is possibly no more fatuous than the pseudo-sophistication with which TV soft-drinks are downed or toothpaste applied, there is a sad difference between enticing a viewer into sipping Oopsie-Cola and gulling him into downing bourbon.

Although the United States and the U.S.S.R. have been arguing whether there shall be four, five or six top assistants, the most important element in the situation is not the number of deputies but the manner in which these deputies are to do their work.

Although today's trucks are as fast as passenger cars, a truck driver has to be a sensible person and guard against hogging the road.

Although they are forbidden to sit with the customers, the dancers are sometimes proffered drinks, and most of them can bolt one down in mid-shimmy.

Although there are many sound reasons for adopting uniform and coordinated fiscal years in Rhode Island, there are also certain difficulties encountered.

Although the site may not contain the features themselves, there are often opportunities to include them as additional interest to the site.

Although the play does show a certain structural amateurishness ( there are eleven acts varying in length from twenty-five seconds to an hour and a half ), the statement it makes concerning the ceaseless yearning and searching of youth is profound and worthy of our attention.

Although there is no question but that the process of washing fabrics involves a number of phenomena which are related together in an extremely complicated way and that these phenomena and their interrelations are not well understood at the present, this section attempts to present briefly an up-to-date picture of the physical chemistry of washing either fabrics or hard surfaces.

Although the standard deviation values on which spread of the lines is based are relatively larger for those centers which begin to ossify early ( Table 1 ), there are considerable differences in this value between centers having the closely timed Onsets.

Although in both emotions sympathetic symptoms are present, different autonomic-somatic patterns underlie aggression and anxiety, respectively, as indicated by the rate of the excretion of the catecholamines, the state of the muscle tone, and the Mecholyl test.

Although we are still far from a complete understanding of these problems, as a first approximation, it is suggested that alterations in the hypothalamic balance with consequent changes in the hypothalamic-cortical discharges account for major changes in behavior seen in various moods and states of emotions in man and beast under physiological circumstances, in experimental and clinical neurosis, and as the result of psychopharmacological agents.

Although the inner functions of religion are not of direct significance in social organization, they have important indirect consequences.

Although the Brandywine population is still predominantly rural, `` there are indications of a consistent and a statistically significant trend away from the older and relatively isolated rural communities.

Although science has given us more effective materials, preparations from anise, castorbean, colchicum, nux vomica, mustard, fennel, and stramonium are familiar to many for the relief of human ailments.

Although the Administration's program cut crop acreage to the lowest point since 1934, farmers, with the help of extra fertilizer and good weather, are getting such high yields per acre that many are being forced to buy new harvesting machines.

Although progress has been made in America's system of libraries it still falls short of what is required if we are to maintain the standards that are needed for an informed America.

Although the theological forms of the past continue to exist in a way they do not in a more secularized situation, the striking thing is the rapidity with which they are being reduced to a marginal existence.

Although there are landscapes in the show ( one of the strongest is a vista of `` Gloucester Harbor '' in 1915 ), the human element was the compelling factor in Sloan's art.

Although Kemp coaxed Bush to support a $ 4 billion housing program that encouraged public housing tenants to buy their own apartments, the Democratic Congress allocated only $ 361 million to the plan.

Although men participated in pederastic relationships outside of marriage, there is no clear evidence that women were allowed or encouraged to have same-sex relationships before or during marriage as long as their marital obligations were met.

Although Juan Perón encouraged the actions of José López Rega, supported the right-wing unionists and denied preferential promotions to the Montoneros, they thought that his actions were simply a strategic masquerade, and that he actually supported the Montoneros ' projects.

Although electronic documents are encouraged, networked printers are installed in various campus locations for hard copy documents.

Although pressure of this sort no doubt encouraged Stroessner to legalize some internal opposition parties, it failed to make the Paraguayan ruler become any less a personalist dictator.

Although it was initially a court of appeal, King Henry, Wolsey and Cranmer encouraged plaintiffs to bring their cases directly to the Star Chamber, bypassing the lower courts entirely.

Although Rome had a native tradition of performance, the Hellenization of Roman culture in the 3rd century BCE had a profound and energizing effect on Roman theatre and encouraged the development of Latin literature of the highest quality for the stage.

Although Washington had been considering retiring, both sides encouraged him to remain in office to bridge factional differences.

Although Holst had no such patriotic intentions when he originally composed the music, these adaptations have encouraged others to draw upon the score in similar ways throughout the 20th Century.

Although James had always adopted male favourites among his courtiers, he now encouraged them to play a role in the government.

Although her parents encouraged her to prepare herself for life as a wife and mother, she attended the École Normale de Neuilly in Paris.

Although he later admitted that he had no interest in being a candidate himself for public office, Peck encouraged one of his sons, Carey Peck, to run for political office.

Although he was a staunch Republican, Warner encouraged film projects that promoted the agenda of Democratic President Franklin D. Roosevelt's New Deal.

Although the coup was not led by Guéï, the popular general was encouraged out of retirement to head the junta until the next elections.

Although some have toilets, there are minimal other facilities and visitors are encouraged to take adequate food, water, fuel and firewood with them.

Although his march failed, Coxey's Army was an early attempt to arouse political interest in an issue that grew in importance until the Social Security Act of 1935 encouraged the establishment of state unemployment insurance programs.

Although only in his mid-thirties, his students described him as an outstanding teacher, who, rather than imposing his own ideas, encouraged his pupils to find their own voice.

Although Wolf admired Liszt, who had encouraged him to complete the work, he felt Liszt's own music too dry and academic and strove for color and passion.

Although some members of the society encouraged granting freedom to slaves, the majority saw the relocation as a means to reduce the number of free blacks in the United States and thus help preserve the institution of slavery.

Although the economic downturn has encouraged some collectors to sell art, others are unwilling to sell in a market which may yield only bargain prices.

* Although not required by law or military regulation, members of the uniformed services are encouraged to render salutes to recipients of the Medal of Honor as a matter of respect and courtesy regardless of rank or status.

Although these regulations seem to provide a strong legal framework for controlling the commerce involving big cats, international organizations such as the World Wildlife Fund ( WWF ) have encouraged the U. S. to further strengthen these laws.

Although its existence in Indonesia pre-dates Islam, batik reached its high point in the royal Muslim courts such as Mataram and Yogyakarta, whose Muslim rulers encouraged and patronised batik production.

Although he agrees Wayne encouraged Arness to take the role, Warren says, " I hired Jim Arness on the strength of a picture he's done for me ...