Additionally, members may need to adjust team roles due to stress, fatigue, injury, or other circumstances.

A statute of repose limits the time within which an action may be brought and is not related to the accrual of any cause of action ; the injury need not have occurred, much less have been discovered.

Hepatotoxicity and drug-induced liver injury account for a substantial number of failures of new drugs in development and market withdrawal, highlighting the need for screening assays such as stem cell-derived hepatocyte-like cells, that are capable of detecting toxicity early in the drug development process.

The need for imaging in patients who have suffered a minor head injury is debated.

He had operated his races over local roads in Nassau County during the first decade of the 20th century, but the killing of two spectators and the injury of many others showed the need to eliminate racing on residential streets.

In these cases, however, the dog's owners need to be very careful, since any injury or bumps to the animal's head could cause significant brain damage, as well as conditions like epilepsy.

Hyperbaric oxygen therapy has been suggested by case reports — though as of 2011 not proven in controlled randomized trials — to be an effective adjunctive therapy for crush injury, compartment syndrome, and other acute traumatic ischemias, by improving wound healing and reducing the need for repetitive surgery.

In the parent-child concept, tickling establishes at an early age the pleasure associated with being touched by a parent with a trust-bond developed so that parents may touch a child, in an unpleasant way, should circumstances develop such as the need to treat a painful injury or prevent harm from danger.

His theory was soon attacked by several contemporary physiologists, such as Ludimar Hermann, who maintained that a living untouched tissue, such as a muscle, is not the subject of electric currents so long as it is at rest, it is isoelectric in substance, and therefore need not be supposed to be made up of electric molecules, all the electric phenomena which it manifests being due to internal molecular changes associated with activity or injury.

Modern, glued-in windshields contribute to the vehicle's rigidity, but the main force for innovation has historically been the need to prevent injury from sharp glass fragments.

There were published reports stating that Prior would need reconstructive Tommy John surgery on his elbow, but both Prior and the Cubs denied this, saying that his achilles tendon injury is the only reason he missed time in 2004.

About one percent of people who receive treatment for MTBI need surgery for a brain injury.

By the time he returned to the Mets in 1969, manager Gil Hodges had a very capable young pitching rotation that included Tom Seaver, Jerry Koosman and Gary Gentry and had no need for McGraw as a starter until Koosman went down with an injury in May.

Kiprusoff again declined an invitation to play at the 2006 Winter Olympics citing the need to rest a hip injury.

Similar to desktop keyboards and input devices, if a user overuses keys which need hard presses and / or have small and unergonomic layouts, it could cause thumb tendonitis or other repetitive strain injury.

** to eliminate the need of the poor to seek redress from the king's principal auditors for each small injury.

While traveling with Peter, Susan and beavers Father Christmas gives them gifts ; Lucy is given a vial with magical cordial that can heal almost any injury, and a small dagger with which to defend herself " at great need ".

The Chief Justice of Queensland, Paul de Jersey AC, said the laws have " brought about marked erosion of a fundamental right to adequate compensation " for injury and that the critical issue now is " the need for active reconsideration of whether the so-called reforms have proven justified, or should be wound back " ( February 2006 address to the Australian Lawyers Alliance ).

Like the rest of his species, Krona possesses enhanced physical abilities, vast psionic powers ( including telepathy and telekinesis ) and virtual immortality ( he does not need to breathe, eat or sleep, and can regenerate from any injury at an accelerated rate ).

The Dynamo recognized the need for help at the forward position after Brian Ching sustained a hamstring injury in their home opener against Real Salt Lake.

As traumatic brain injury and combat stress reaction have very different causes yet result in similar neurologic symptoms, researchers emphasize the need for greater diagnostic care.

Because of the events resulting from ischemia and glutamate receptor activation, a deep chemical coma may be induced in patients with brain injury to reduce the metabolic rate of the brain ( its need for oxygen and glucose ) and save energy to be used to remove glutamate actively.

Some experimental treatments, such as systemic hypothermia, have been performed in isolated cases in order draw attention to the need for further preclinical and clinical studies to help clarify the role of hypothermia in acute spinal cord injury.

There may be a reduced level of consciousness, sensory misperceptions and illusions, disturbances of sleep, drowsiness, disorientation to time, place, or person, and problems with memory ," which is to be expected in people who suffer head injury, and contributes to the ' need ' for compulsion to treatment under law, as people are unwilling to volunteer to such barbarism.

Amputation has also been used as a tactic in war and acts of terrorism ; it may also occur as a war injury.

Most removals of the clitoris occur as female genital mutilation, defined by the World Health Organisation as " all procedures involving partial or total removal of the external female genitalia or other injury to the female genital organs whether for cultural, religious or other non-therapeutic reasons.

There are simple devices available to attach to the hinge side, ensuring that this type of injury does not occur.

In some car accidents, injury to occupants from the movement of car doors may occur.

If a handler always treats firearms as capable of being discharged at any time, the handler is more likely to take precautions to prevent an unintentional discharge and to avoid damage or injury if one does occur.

Sudden falls, sometimes resulting in major injury to the skull or other bones, can occur, even from walking on minimally-irregular ground or from other minor imbalances outside or in the home, due to weakness of quadriceps and gluteus muscles depriving the patient of automatic posture maintenance.

In general, more serious problems with memory occur due to traumatic brain injury or neurodegenerative disease.

# No experiment should be conducted where there is a prior reason to believe that death or disabling injury will occur ; except, perhaps, in those experiments where the experimental physicians also serve as subjects.

Such displacement may occur via an injury.

Onset may be immediate or may not occur until years after the disabling injury.

Episodic analgesia may occur under special circumstances, such as in the excitement of sport or war: a soldier on the battlefield may feel no pain for many hours from a traumatic amputation or other severe injury.

Brain injury may still occur in a TIA lasting only a few minutes.

Loss of consciousness may occur as the result of traumatic brain injury, brain hypoxia ( e. g., due to a brain infarction or cardiac arrest ), severe poisoning with drugs that depress the activity of the central nervous system ( e. g., alcohol and other hypnotic or sedative drugs ), severe fatigue, and other causes.

Very serious injury can also occur if the jumper's neck or body gets entangled in the cord.

It can occur without a known cause or as the result of a lung disease or acute lung injury.

Patient may become comatose, and death or brain injury may occur.

Collisions occur both with large commercial vessels and recreational boats and cause injury to whales or smaller cetaceans.

Brain failure after clinical death is now known to be due to a complex series of processes ( reperfusion injury ) that occur after blood circulation is restored, especially processes that interfere with blood circulation during the recovery period.

ITBS can also occur where the IT band connects to the hip, though this is less likely as a sports injury.

Penis removal may occur through unintentional genital injury.

Inappropriate opening of the mitochondrial permeability transition pore ( MPTP ) manifests in ischemia ( blood flow restriction to tissue ) and reperfusion injury ( damage occurring after ischemia when blood flow returns to tissue ), after myocardial infarction ( heart attack ) and when mutations in mitochondrial DNA polymerase occur.

Most other no-contests in boxing occur when unusual circumstances, which would include instances such as a bout being rained out, ring falling apart, or an unexpected injury caused by something outside of the boxer's control.

In infants, some elderly individuals, and those with neurological injury, urination may occur as an involuntary reflex.

Although they usually occur at the site of an injury, keloids can also arise spontaneously.