Anthemius was also a capable mathematician.

Justinian also had Anthemius and Isidore demolish and replace the original Church of the Holy Apostles built by Constantine with a new church under the same dedication.

A few days after the death of Anthemius, Ricimer also died, on August 9 or 19 ; his nephew Gundobad Magister militum was elevated in his place.

Leo's reign was also noteworthy for his influence in the Western Roman Empire, marked by his appointment of Anthemius as Western Roman Emperor in 467.

Isidore of Miletus and Anthemius of Tralles, the architects of the famous Hagia Sophia in Constantinople, also contributed towards mathematical theories concerning architectural form, and the perceived mathematical harmony needed to create a multi-domed structure.

However, Leo had also send Modestus, another messenger, to Anthemius with a different set of instructions.

Agathias speaks also with great praise of his four brothers, Anthemius, Dioscorus, Metrodorus, and Olympius, who were all eminent in their several professions.

Anthemius, with the aristocracy and the people of the city faced the Goth magister militum and the barbaric units of the army, which included Odoacer's men.

In 471, the year in which Leo held his fourth consulate with the Praetorian prefect of Italy Caelius Aconius Probianus as colleague, the two emperors strengthened their bonds with a marriage between Anthemius ' son, Marcian, and Leo's daughter, Leontia ; Marcian was honoured with his second consulate the following year, this time chosen by the Eastern court.

The new Emperor, however, had been chosen by the Eastern court, and, despite the bond of the marriage between Ricimer and Anthemius ' daughter, Alypia, they were not on good terms.

**** From marriage between Marcia Euphemia and Anthemius.

Marcia Euphemia was the only known daughter of Marcian, and she was married to Anthemius, later Western Roman Emperor.

Ricimer then quarreled with Anthemius, and besieged him in Rome ( which this time put up a vigorous defence and surrendered only after more months of starvation ).

* Anthemius marries Marcia Euphemia, daughter of Marcian, and is elevated to the rank of comes.

His mother Lucina, born c. 400, descended from Flavius Philippus, Praetorian prefect of the East in 346, and was the daughter of the influential Flavius Anthemius, Praetorian prefect of the East ( 404 – 415 ) and Consul in 405.

This succession of honourable events – the wedding with Marcian's daughter ; a promotion to an important military rank, but with administrative rather than military tasks ; the prestigious rank of patricius and the highest military position ; the consulate held with an Emperor as colleague – suggests that Marcian had selected Anthemius as a possible candidate for the Eastern or Western throne.

He was survived by his daughter Euphemia and his son-in-law Anthemius.

Avitus was in turn overthrown ( but not killed ) by his own master of the soldiers, Ricimer, who was responsible for both the installation and removal of Majorian and of Libius Severus, the removal of Anthemius ( installed as the Eastern Emperor's candidate ), and the installation of Olybrius – husband of Valentinian III's daughter ( and Petronius Maximus's stepdaughter ) Placidia, and loosely a member of the Theodosian dynasty.

Leo I wife Verina bore him at least two daughters, one of whom married the son of Anthemius, whom Leo I installed as Emperor in the West in 467 ( and whose daughter married the formidable " Shadow Emperor " Ricimer ), and the other of whom was Ariadne, who married the Isaurian leader Tarasikodissa ; Tarasikodissa was appointed master of the soldiers and adopted the name Zeno.

Procopius was the son of Anthemius and of Marcia Euphemia, daughter of the Easter Roman Empire.

* Alypia, daughter of Procopius Anthemius, wife of Ricimer.

Under Anthemius he was raised to the rank of patrician, becoming a possible threat to Ricimer, the powerful kingmaker behind the western throne.

In 472, the Western Roman Empire was plagued by a civil war between Emperor Anthemius and his Magister militum ( commander in chief of the army ), Ricimer.

On 25 March 467, Leo I, with the consent of Ricimer, designated Anthemius Western Emperor as Caesar and sent him to Italy with an army led by the Magister militum per Illyricum Marcellinus.

In 470 the consuls were Messius Phoebus Severus, Anthemius ' old friend and fellow student at Proculus ' school, and the Magister militum per Orientem Jordanes.

Anthemius stayed in service under the new Emperor ; as magister militum, his task was to defend the Empire from the barbaric populations pressing on its border.

Despite the presence of a strong candidate to the purple, the magister militum and Marcian's son-in-law Anthemius, the choice was quite different.

* Procopius, magister militum, father of Emperor Procopius Anthemius

In 472, Anthemius ( Western Roman Emperor ) was involved in a civil war with his magister militum and son-in-law Ricimer.

Relations between Ricimer, de facto ruler, and emperor Anthemius deteriorates completely.

In 472 Olybrius was sent to Italy by the Eastern Emperor, Leo I the Thracian, ostensibly to mediate between Ricimer and the Western Emperor, Anthemius, whom Ricimer had trapped in a siege of Rome.

Ricimer had Anthemius killed and Olybrius acclaimed Emperor ( July 11, 472 ).

Then Ricimer besieged the part of Rome where Anthemius was for several months until the lawful Emperor was abandoned by his partisans, captured in a church and put to death by Gundobad, Ricimer's nephew.

As Aspar could not sit on the throne because of his barbaric origin, he opposed Anthemius whose prestige would have made him independent and chose a low-ranking military officer, Leo ; in the West, as his barbaric origin barred Ricimer from the throne, it was Majorian who received the purple.

The tipping point of their relationship was the trial of Romanus, an Italian senator, who was a patricius and was supported by Ricimer, whom Anthemius accused of treachery and condemned to death in 470.

Ricimer had gathered 6, 000 men for the war against the Vandals, and after the death of Romanus he moved with his men to the north, leaving Anthemius in Rome.

The Eastern Roman Emperor, Leo I, sent Olybrius to mediate between Ricimer and Anthemius but, according to John Malalas, had sent a secret letter to Anthemius, urging him to kill Olybrius.

Ricimer blockaded Anthemius in Rome ; five months of fighting followed.

* 472 – Ricimer kills Anthemius and makes Olybrius new western emperor.

The most pointed example of this is the Suebian general Ricimer, who became a " Shadow Emperor " by deposing Avitus, installing and subsequently deposing ( and murdering ) Majorian, installing ( and possibly subsequently murdering ) Libius Severus, ruling the Empire himself during an eighteen-month interregnum, deposing and killing Anthemius, and installing Olybrius.

This message asked Anthemius to arrange the deaths of both Ricimer and Olybrius.