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Benzodiazepines tend to exert their hypnotic effects at high dosage compared to the more moderate dosage needed for anxiolytic effects to be felt.
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Benzodiazepines and exert
Benzodiazepines and their
* Benzodiazepines are well known for their strong muscle-relaxing properties and can be useful in the treatment of muscle spasms, although tolerance often develops to their muscle relaxant effects.
Benzodiazepines share a similar chemical structure, and their effects in humans are mainly produced by the allosteric modification of a specific kind of neurotransmitter receptor, the GABA < sub > A </ sub > receptor, which increases the conductance of this inhibitory channel ; this results in the various therapeutic effects as well as adverse effects of benzodiazepines.
Benzodiazepines are the most well-known and most frequently-prescribed hypnotic medications, although their use in recent years is being increasingly replaced by newer nonbenzodiazepine hypnotic drugs and the hormone melatonin.
Benzodiazepines are effective in the short term but tolerance to their hypnotic effects develops after 1 or 2 weeks, thus making them ineffective for long-term use.
Benzodiazepines may be useful in acute treatment of severe symptoms but the risk benefit ratio is against their long-term use in phobic disorders.
Benzodiazepines gained widespread use in the 1970s for anxiety and depression, until dependency problems curtailed their popularity.
Benzodiazepines may influence neurosteroid metabolism by virtue of their actions on translocator protein ( TSPO ; " peripheral benzodiazepine receptor ").
Benzodiazepines and hypnotic
Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid ( GABA-A ), resulting in sedative, hypnotic ( sleep-inducing ), anxiolytic ( anti-anxiety ), anticonvulsant, and muscle relaxant properties ; also seen in the applied pharmacology of high doses of many shorter-acting benzodiazepines are amnesic-dissociative actions.
Benzodiazepines possess sedative, hypnotic, anxiolytic, anticonvulsant, muscle relaxant, and amnesic actions, which are useful in a variety of indications such as alcohol dependence, seizures, anxiety, panic, agitation and insomnia.
Benzodiazepines, a class of psychoactive drugs called the " minor " tranquilizers, have varying hypnotic, sedative, anxiolytic, anticonvulsant, and muscle relaxing properties, but they may create the exact opposite effects.
Benzodiazepines ( or " benzos ") are fast-acting hypnotic sedatives that are also used to treat GAD and other anxiety disorders.
Benzodiazepines and effects
Prescription hypnotics ( Benzodiazepines and Nonbenzodiazepines included ) should therefore be taken for the shortest duration of time with the least frequency possible, so as to avoid tolerance, drug dependence, and the adverse effects of long term use.
Benzodiazepines, such as lorazepam, enhance the effects of GABA at the GABA < sub > A </ sub > receptor via increasing the frequency of opening of the chloride ion channel on the GABA < sub > A </ sub > receptors ; which results in the therapeutic actions of benzodiazepines.
Benzodiazepines are prescribed for generalized anxiety disorder and show beneficial effects in the short term.
Benzodiazepines including nitrazepam may inhibit the glucuronidation of morphine leading to increased levels of and prolongation of the effects of morphine in rat experiments.
Benzodiazepines and at
Benzodiazepines should be prescribed to the elderly only with caution and only for a short period at low doses.
Benzodiazepines and high
Benzodiazepines and more
Benzodiazepines such as midazolam are more commonly used due largely to a lack of a marketing effort by the pharmaceutical companies.
Benzodiazepines and moderate
Benzodiazepines are sometimes used in the treatment of acute anxiety, as they bring about rapid and marked or moderate relief of symptoms in most individuals ; however, they are not recommended beyond 2 – 4 weeks of use due to risks of tolerance and dependence and a lack of long-term effectiveness.
Benzodiazepines and for
Benzodiazepines are usually administered orally ; however, very occasionally lorazepam or diazepam may be given intravenously for the treatment of panic attacks.
Benzodiazepines are the preferred choice in the management of alcohol withdrawal syndrome, in particular, for the prevention and treatment of the dangerous complication of seizures and in subduing severe delirium.
* Benzodiazepines are sometimes used for obsessive compulsive disorder, although they are generally believed to be ineffective for this indication ; effectiveness was, however, found in one small study.
Benzodiazepines have a reputation with patients and doctors for causing a severe and traumatic withdrawal ; however, this is in large part due to the withdrawal process's being poorly managed.
Benzodiazepines have widely supplanted barbiturates for treatment of almost all conditions in developed countries due to a much greater therapeutic ratio and less proclivity for overdose and toxicity.
Benzodiazepines, including diazepam, nitrazepam, and flunitrazepam, account for the largest volume of forged drug prescriptions in Sweden, a total of 52 % of drug forgeries being for benzodiazepines.
Benzodiazepines such as Ativan and Klonopin are effective adjunctive treatment agents for reducing irritability and anxiety during acute mania, and sometimes during maintenance medication therapy, but long-term use can result in dependency.
Benzodiazepines can be used for sedation before or after surgery and can be used to induce and maintain general anesthesia.
Benzodiazepines are also used for sedation during procedures that do not require general anesthesia.
Benzodiazepines, including diazepam, nitrazepam, and flunitrazepam account for the largest volume of forged drug prescriptions in Sweden, a total of 52 % of drug forgeries being for benzodiazepines, suggesting benzodiazepines are a major prescription drug class of abuse.
Benzodiazepines and be
Benzodiazepines may also be indicated to cover the latent periods associated with the medications prescribed to treat an underlying anxiety disorder.
Benzodiazepines have robust efficacy in the short-term management of generalized anxiety disorder ( GAD ), but were not shown to be effective in producing long-term improvement overall.
Benzodiazepines are also used to calm the acutely agitated individual and can, if required, be given via an intramuscular injection.
Benzodiazepines can be given to curb the patient's agitation, and supportive care with oxygen, hydration, and symptomatic treatment is often provided.
A review paper found Benzodiazepines to be effective in alleviating the symptoms of tardive dyskinesia.
Benzodiazepines and any other form of mind or mood altering addictive drug should not be used on patients with addictive history.
Benzodiazepines and in particular nitrazepam and flunitrazepam should therefore be prescribed with caution in the elderly.
Benzodiazepines may be used for insomnia, although it's very important to note that benzodiazepine withdrawal is known to be severe and long-lived.
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