By 1247, the Nicaeans had effectively surrounded Constantinople, with only the city's strong walls holding them at bay, and the Battle of Pelagonia in 1258 signaled the beginning of the end of Latin predominance in Greece.

By May 1247, as-Salih Ayyub was master of Syria south of Lake Homs, having gained Banyas and Salkhad.

By 1243 was recovered most of the Duchies of Poznań and Gniezno, in 1244 Kalisz, in 1247 Santok, and in 1249 Wieluń.

By 1247, there were also women at the Abbey.

By May 1247 he was back in royal service, for in that month King Henry III of England sent him overseas.

By 1247, the Christians had lost power bases in Tiberias, Mount Tabor, Belvoir and Ascalon.

By failing to do as he was told instantly -- to take out a permit or return the gun to his car -- he had played into Lord's hands.

By 1898, rustling losses had been driven down to the lowest level ever seen in Wyoming.

By the death of his father in 1888 he had come into possession of the family estate and had re-assumed its traditions.

By the time Lilian had been graduated from public school, her parents were doing quite well.

) By the time the streetcar pulled away, he had fallen in love with Paula.

By this time she had learned that it was futile to argue with her young husband, yet the uncomfortable fact remained: the American Congregationalists were sending them as missionaries to the Far East and paying their salaries.

By the age of six young Johnny indicated that he had the call.

By September 1940 the Suite had developed into a collection of six songs, `` four spirituals, a dream, and a lullaby ''.

By now he had become Regius Professor of Modern History at Cambridge and had been honored by the award of the Order of Merit.

By both standards Thomas had the right to be proud.

By June 19, 1788, he had presented himself to its Commander in Chief, the Governor of the Southern Provinces, the Director of the War College -- The Prince.

By 1783 her legions had managed to annex the Crimea amid scenes of wanton cruelty and now, in this second combat with the Crescent, were aiming at suzerainty over all of the Black Sea's northern shoreline.

By this time word had got around that an American doctor was on the premises.

By this time Woodruff had accurately measured Pike as a man of great personal pride, a man who would fly into a towering rage if his integrity were questioned, and who would be anxious to avenge himself.

By 1834 the art of oratory had reached a very high level in the United States as a literary form.

By the time he was under the covers he had forgotten about seeing Kate.

By 1937 he had clarified his intentions to serve his people: `` I have striven for clarity and melodious idiom, but at the same time I have by no means attempted to restrict myself to the accepted methods of harmony and melody.

By the time the film was released we were three million dollars over-spent, war was imminent and the public apparently had forgotten all about Mother Cabrini.

By this time Churchill was not so cordial toward moving Poland westward as he had been at Teheran, where he and Eden had both heartily approved the idea.

By December, 1958, when ' Abdallah Ibrahim became President of the Council, elections had even greater importance.

By 800 social and cultural security had been achieved, at least on a simple plane ; ;

By this time large numbers of the audience had left the hall.

By the 16th century the barbican had been dismantled to make way for houses and the moat had begun to be reoccupied for housing ; by 1600 the moat was almost entirely silted up and houses had been built all around the edge of the bailey wall.

By 2 June 1926 his troops had reoccupied Changsha.

By now Harmony could see that most of the adults in the train were winded and resting, or else siphoned off from the games by the challenging lure of the great cliff towering above them.

By the same test predispositions destructive of human personality exercise their most sinister impact, with the result that men of good will are often trapped and nullified.

By comparing reaction cells sealed from the same manifold temperature dependency corresponding to activation energies ranging from 11 to 18 Af was observed while dependence on the first power of the light intensity seemed to be indicated in most cases.

By all means the most important distinction is that between those total-cost apportionments which superimpose a distribution of admittedly unallocable cost residues on estimates of incremental or marginal costs, and those other apportionments which recognize no difference between true cost allocation and mere total-cost distribution.

By fall, 443 survivors of this arduous journey were clustered about Fort Snelling, but most of them were sent on to Galena and St. Louis, with a few going as far as Vevay, Indiana, a notable Swiss center in the United States.

By relaxing the throat muscles and expanding the oral cavity well into the frontal sinuses, she could direct the vowel sounds into the most felicitous position for proper reproduction through her throat microphone.

By 1850, Luanda was one of the greatest and most developed Portuguese cities in the vast Portuguese Empire outside Mainland Portugal, full of trading companies, exporting ( together with Benguela ) palm and peanut oil, wax, copal, timber, ivory, cotton, coffee, and cocoa, among many other products.

By the end of the 14th century, most of Anatolia was controlled by various Anatolian beyliks.

By some estimates, this might account for most of the internal radiation damage, as the recoil nuclei are typically heavy metals which preferentially collect on the chromosomes.

The largest species are red alder ( A. rubra ) on the west coast of North America, and black alder ( A. glutinosa ), native to most of Europe and widely introduced elsewhere, both reaching over 30 m. By contrast, the widespread Alnus viridis ( green alder ) is rarely more than a 5 m tall shrub.

By a probably euphonic inversion the translator of Irenaeus and the other Latin authors have Abraxas, which is found in the magical papyri, and even, though most sparingly, on engraved stones.

By the middle of the 19th century, industrialisation swept away most of the city's medieval rules of production and commerce, although the entirely corrupt remains of the city's mediæval constitution was kept in place ( compare the famous remarks of Georg Forster in his Ansichten vom Niederrhein ) until 1801, when Aachen became the " chef-lieu du département de la Roer " in Napoléon's First French Empire.

By the early 1960s, most of East and Central Africa, where the majority of the Ismāʿīlī population on the continent resided including Tanganyika, Kenya, Uganda, Malagasy, Rwanda, Burundi and Zaire, had attained their political independence.

By the time Alexios ascended the throne, the Seljuqs had taken most of Asia Minor.

By seeking close alliances with powerful noble families, Alexios put an end to the tradition of imperial exclusivity and coopted most of the nobility into his extended family and, through it, his government.

By 1094, Yusuf had annexed most major taifas, with the exception of the one at Zaragoza.

By the mid-16th century, they were in common use in most of Europe.

By the 1890s, the company was the largest and most profitable industrial enterprise in the world.

By a public decree, this fine work was placed in one of the stanze of the Vatican hitherto reserved for the most precious works of antiquity.

By contrast, while defendants in most civil law systems can be compelled to give a statement, this statement is not subject to cross-examination by the prosecutor and not given under oath.

By this time most had expected him to have wasted away, or to have gone insane in his solitary confinement.

By the time Marlborough had closed down the Ramillies campaign he had denied the French most of the Spanish Netherlands west of the Meuse and north of the Sambre – it was an unsurpassed operational triumph for the English Duke.

By the mid 1960s, binary addressing had become the standard architecture in most computer designs, and main memory sizes were most commonly powers of two.

By making these data available to local public health officials in real time, most models of anthrax epidemics indicate that more than 80 % of an exposed population can receive antibiotic treatment before becoming symptomatic, and thus avoid the moderately high mortality of the disease.