By the mid-4th century BC, however, the northern Greek kingdom of Macedon was becoming dominant in Athenian affairs, despite the warnings of the last great statesman of independent Athens, Demosthenes.

By the mid-4th century, the city was counted in a Roman manuscript as one of the four capitals of the world, alongside Rome, Alexandria, and Constantinople.

By the end of the nineteenth century, in 1893, when the Big Three, Columbia, and Penn were populous centers of learning, Dartmouth graduated only sixty-nine.

By the end of the century the Roman Catholic Church was beginning to make itself felt, mainly through such institutions as hospitals but also through its attitude towards organized labour.

By the 27th century BC Egyptian writing had a set of some 24 hieroglyphs which are called uniliterals, to represent syllables that begin with a single consonant of their language, plus a vowel ( or no vowel ) to be supplied by the native speaker.

By the tenth century two other forms can be distinguished namely Canaanite and Aramaic.

By the end of the 14th century, most of Anatolia was controlled by various Anatolian beyliks.

By the 6th century BC, the Celtic La Tène culture was well established.

By the mid-19th century scientists began to arrive en masse to study the geology and ecology of the region.

By the late 5th century BC, philosophers might separate Aphrodite into two separate goddesses, not individuated in cult: Aphrodite Ourania, born from the sea foam after Cronus castrated Uranus, and Aphrodite Pandemos, the common Aphrodite " of all the folk ," born from Zeus and Dione.

By the beginning of the 8th century, these kingdoms had either been conquered by Nicene neighbors ( Ostrogoths, Vandals, Burgundians ) or their rulers had accepted Nicene Christianity ( Visigoths, Lombards ).

By the middle of the 19th century, industrialisation swept away most of the city's medieval rules of production and commerce, although the entirely corrupt remains of the city's mediæval constitution was kept in place ( compare the famous remarks of Georg Forster in his Ansichten vom Niederrhein ) until 1801, when Aachen became the " chef-lieu du département de la Roer " in Napoléon's First French Empire.

By the 6th century Alexander's commentaries on Aristotle were considered so useful that he was referred to as " the commentator " ().

By the mid-16th century, they were in common use in most of Europe.

By the standards of 19th century tycoons, Carnegie was not a particularly ruthless man but a humanitarian with enough acquisitiveness to go in the ruthless pursuit of money ; on the other hand, the contrast between his life and the lives of many of his own workers and of the poor, in general, was stark.

By the 7th century BC, much of the Assyrian population used Akkadian influenced Eastern Aramaic and not Akkadian itself.

By the 4th century AD artists had started debating in writing over the proper goals of art as well.

By the end of the twentieth century " Negro " had come to be considered inappropriate and was rarely used and perceived as a pejorative.

By the early 5th century Britain had been Roman for over three hundred and fifty years.

By the 1st century BC, Aediles were elected in July, and took office on the first day in January.

By the 16th century, a cappella polyphony had further developed, but gradually, the cantata began to take the place of a cappella forms.

By the 19th century orchestral music in Europe had standardized the string section into the following homogeneous instrumental groups: first violins, second violins, violas, cellos, and double basses.

By the 3rd century BC, the rival armies of Carthage and Rome began to invade and fight for control of the Iberian Peninsula.

By the 5th century AD, Rome was in decline and the Roman predecessor town of Alicante, known as Lucentum ( Latin ), was more or less under the control of the Visigothic warlord Theudimer.

By the end of the 18th century there were no factories or mills and only a few small cottage industries along the border with Zurich.

By the beginning of the twentieth century, Steiner's interests turned to explicitly spiritual areas of research.

By the time they reach that age, however, Aristotle no longer worries about the evil influence of comedies.

By reminding ourselves of these factors in the situation, we should, I am sure, come to a fresh realization, however painful it be, that the battle between Parker and his neighbors was fought in earnest.

By 1994, however, the Armenian Government had launched an ambitious IMF-sponsored economic liberalization program that resulted in positive growth rates in 1995-2005.

By 1994, however, the Armenian Government had launched an ambitious IMF-sponsored economic program that has resulted in positive growth rates in 1995-99.

By the 1990s, however, mentalité history had become interdisciplinary to the point of fragmentation, but still lacked a solid theoretical basis.

By age three, however, her mother changed her name to Elizabeth Sewall Alcott, after her own mother.

By this time Naples seems to have become tired of his music ; the Romans, however, appreciated it better, and it was at the Teatro Capranica in Rome that he produced some of his finest operas ( Telemaco, 1718 ; Marco Attilio Regolò, 1719 ; La Griselda, 1721 ), as well as some noble specimens of church music, including a mass for chorus and orchestra, composed in honor of Saint Cecilia for Cardinal Acquaviva in 1721.

By 1987, however, the USSR withdrew its opposition, concluding the SDI posed no threat.

By 1902, however, due to the Governor of ` Akka being supportive of ` Abdu ' l-Bahá, the situation was greatly eased ; while pilgrims were able to once again visit ` Abdu ' l-Bahá, he was confined to the city.

" By 1923 however, Gropius was no longer evoking images of soaring Romanesque cathedrals and the craft-driven aesthetic of the " Völkisch movement ", instead declaring " we want an architecture adapted to our world of machines, radios and fast cars.

By the mid-1990s, however, companies were beginning to ask what the return was on the investment they had made in this loosely controlled PC software buying spree.

By 1972, however, with only a minimum of work done on the I-95 right of way and none on the potentially massively disruptive Inner Belt, Governor Francis Sargent put a moratorium on highway construction within the MA-128 corridor, except for a short stretch of Interstate 93.

By now the rebel forces were said to have numbered 230, 000, however, this number should be treated with scepticism — Dio's account is known only from a late epitome, and ancient sources commonly exaggerate enemy numbers.

By the early 2000s ( decade ), however, the university quietly reexamined its position on accreditation as degree mills proliferated and various government bureaucracies, such as law enforcement agencies, began excluding BJU graduates on the grounds that the university did not appear on appropriate federal lists.

By 1967, however, Frei encountered increasing opposition from leftists, who charged that his reforms were inadequate, and from conservatives, who found them excessive.

By the late Bronze Age, however, a series of treaties had established safe passage for merchants around the Eastern Mediterranean, spreading from Minoan Crete and Mycenae in the northwest to Elam and Bahrain in the southeast.

By the fourth century, however, " confessors "— people who had confessed their faith not by dying but by word and life — began to be venerated publicly.

By the late 1870s, however, croquet had been eclipsed by another fashionable game, tennis, and many of the newly-created croquet clubs, including the All England club at Wimbledon, converted some or all of their lawns into tennis courts.

By this time, however, many CBM users had shifted their attention to the 16 / 32-bit Amiga, and the 1581 was mostly sold to remaining GEOS users.

By the mid-19th century, however, the powerful British Empire gave up mercantilism and trade restrictions and introduced the principle of free trade, with few restrictions or tariffs.

By the recent turn of the century, however, his paintings were selling for millions.

By December 1981, however, the U. S. had already begun to support armed opponents of the Sandinista regime.

By 1943 however, large numbers of fleet and light carriers became available, which required larger formations of three or four carriers.

By March 1963 however, after the visit of Colonel Michael Greene of the United States Army, and the resulting ' Greene Plan ,' the pattern of bilaterally agreed military assistance to various Congolese military components, instead of a single unified effort, was already taking shape.