* Assisted Dr. Charles Grob to design, obtain approval for and fund the first FDA-approved study in the U. S. to administer MDMA to humans.

A study of UDV members by the psychiatrist, Charles Grob, of the UCLA School of Medicine, found them to be psychologically and physically healthier than average, and he has recommended ayahuasca as a treatment for depression.

* Bernard Grob, Charles E. Herndon: Television and video systems, Glencoe McGraw-Hill

The films were directed by J. Farrell MacDonald, with casts that included Violet MacMillan, Vivian Reed, Mildred Harris, Juanita Hansen, Pierre Couderc, Mai Welles, Louise Emmons, J. Charles Haydon, and early appearances by Harold Lloyd and Hal Roach.

He excommunicated him after protracted negotiations on 13 April 1346 and directed the election of Charles IV, who received general recognition after the death of Louis in October 1347, ending the schism which had long divided Germany.

On October 10, 1927, Army Chief of Staff General Charles Pelot Summerall directed that a draft bill be sent to Congress " to revive the Badge of Military Merit ".

In 1990 Charles Lane directed and starred in Sidewalk Stories, a low budget salute to sentimental silent comedies particularly Charlie Chaplin's The Kid.

Other films shot in widescreen were the musical Happy Days ( 1929 ) which premiered at the Roxy Theater, New York City, on February 13, 1930, starring Janet Gaynor and Charles Farrell and a 12 year old Betty Grable as a chorus girl ; Song o ’ My Heart, a musical feature starring Irish tenor John McCormack and directed by Frank Borzage ( Seventh Heaven, A Farewell to Arms ), which was shipped from the labs on March 17, 1930, but never released and may no longer survive, according to film historian Miles Kreuger ( the 35mm version, however, debuted in New York on March 11, 1930 ); and the western The Big Trail ( 1930 ) starring John Wayne and Tyrone Power, Sr. which premiered at Grauman's Chinese Theatre in Hollywood on October 2, 1930, all of which were also made in the 70mm Fox Grandeur process.

In a brief the Pope also directed Charles V, Holy Roman Emperor to take energetic measures against heresy.

* 1911: Vanity Fair: directed by Charles Kent.

* 1915: Vanity Fair: directed by Charles Brabin.

Her most famous novel was Madame de ..., published in 1951, which was adapted into the celebrated film The Earrings of Madame de ... ( 1953 ), directed by Max Ophüls and starring Charles Boyer, Danielle Darrieux and Vittorio de Sica.

It was written and directed by Charles Martin Smith and produced by Rob Merilees and the late William Vince.

His career began in the theatre ; he made his first appearance on the London stage in 1958 in Jane Arden's The Party, directed by Charles Laughton, who starred in the production along with his wife, Elsa Lanchester.

It was directed by Charles Jarrott and produced by Hal B. Wallis.

Her performances in Seventh Heaven ( the first of twelve movies she would make with actor Charles Farrell ) and both Sunrise, directed by F. W. Murnau, and Street Angel ( in 1927, also with Charles Farrell ) earned her the first Academy Award for Best Actress in 1928.

Charles and his brother James joined and directed the fire-fighting effort.

Charles found his nephew to be a dedicated Calvinist and patriotic Dutchman, and reconsidered his desire to show him the Secret treaty of Dover with France, directed at destroying the Dutch Republic and installing William as " sovereign " of a Dutch rump state.

* Concerto Palatino, a leading ensemble centered on the cornetto and trombone and directed by Bruce Dickey and Charles Toet.

** Stone of Destiny ( film ), a 2008 film directed by Charles Martin Smith

After the death of Charles II in 1685, Wren's attention was directed mainly to Whitehall ( 1685 – 87 ).

* Gaslight ( 1944 film ), directed by George Cukor, starring Ingrid Bergman and Charles Boyer and Angela Lansbury, based on the play

In the comedy Western film directed by Leo McCarey, Lord Burnstead ( Roland Young ) gambles away his eminently correct English butler, Marmaduke Ruggles ( Charles Laughton ).

* Lost Horizon ( 1973 ), directed by Charles Jarrott ( musical version )

La Grande Illusion ( also known as Grand Illusion ) is a 1937 French war film directed by Jean Renoir, who co-wrote the screenplay with Charles Spaak.

In 1941, NBC Blue aired a sixty minute adaptation of the play as part of their Great Plays series, written by Ranald MacDougall and directed by Charles Warburton, starring Herbert Rudley and Grace Coppin.

With the first of a group of historical novels, The Charles Men ( Karolinerna ), published in 1897-8, he achieved the masterpiece of his career.

The first half of The Charles Men, ending on the climax of the battle of Poltava in 1709, is more dramatically coherent than the second.

the Low Countries, where the Middle Ages were to last for another two centuries and die out only when Charles the Bold of Burgundy met his first defeat in the fields and forests below the walls of Grandson.

Thus the first lines of one of Charles Wesley's hymns are as follows.

Secretary of Defense Robert McNamara, former President of the Ford Motor Company, comes from a generation different from that of Eisenhower's own first Secretary of Defense, Charles Wilson, who had been head of General Motors.

* In 1870 the small City of Ragusa ( Dubrovnik ) became the first small Lifeboat to cross the Atlantic from Cork to Boston with two men crew, John Charles Buckley and Nikola Primorac ( di Costa ), only.

* In 1927, Charles Lindbergh made the first solo non-stop transatlantic flight in an aircraft ( between New York City and Paris ).

Van Vogt's first published SF story, " Black Destroyer " ( Astounding Science Fiction, July 1939 ), was inspired by Voyage of the Beagle by Charles Darwin.

The first major expression of this were the Lambeth Conferences of the communion's bishops, first convened by Archbishop of Canterbury Charles Longley in 1867.

The first actor to portray Hercule Poirot was Charles Laughton.

He invented the first perfusion pump with Charles A. Lindbergh opening the way to organ transplantation.

* 1521 – Martin Luther's first appearance before the Diet of Worms to be examined by the Holy Roman Emperor Charles V and the other estates of the empire.

Common meter hymns were interchangeable with a variety of tunes ; more than twenty musical settings of " Amazing Grace " circulated with varying popularity until 1835 when William Walker assigned Newton's words to a traditional song named " New Britain ", which was itself an amalgamation of two melodies (" Gallaher " and " St. Mary ") first published in the Columbian Harmony by Charles H. Spilman and Benjamin Shaw ( Cincinnati, 1829 ).

Rather than face this ordeal, Alexei fled to Vienna and placed himself under the protection of his brother-in-law, the emperor Charles VI, who sent him for safety first to the Tirolean fortress of Ehrenberg ( near Reutte ), and finally to the castle of Sant ' Elmo at Naples.

King Charles II, who founded the Royal Observatory Greenwich in 1675 instructed the first Astronomer Royal John Flamsteed, ".

* 1858 – The Eiger in the Bernese Alps is ascended for the first time by Charles Barrington accompanied by Christian Almer and Peter Bohren.

* 1892 – Charles Duryea claims to have driven the first automobile in the United States, in Springfield, Massachusetts.

The first European-American settler, Tenney Peabody, arrived in 1833 along with his brother-in-law Charles Blanchard, and a young man named Clark Dowling.

Charles peacefully went into his involuntary retirement, but not without first chastising his nephew for his treachery and asking only for a few royal villas in Swabia, which Arnulf mercifully granted him, on which to live out his final months.

* 1925 – The Great Gatsby by F. Scott Fitzgerald is first published in New York City, by Charles Scribner's Sons.

Wind tunnels were key in the development and validation of the laws of aerodynamics. In 1889, Charles Renard, a French aeronautical engineer, became the first person to reasonably predict the power needed for sustained flight.

The song was first copyrighted in 1835 by the Boston-based music publisher Charles Bradlee, and given the title " The A. B. C., a German air with variations for the flute with an easy accompaniment for the piano forte ".

The first British production of the play in its regular form opened on 7 June 1889 at the Novelty Theatre, starring Janet Achurch as Nora and Charles Carrington as Torvald.