Despite extensive attempts to obtain highly pure reagents, serious difficulty was experienced in obtaining reproducible rates of reaction.

Despite two coup attempts in the following three months, including one by Abeid, Bacar ’ s government remained in power, and was apparently more willing to negotiate with Comoros.

Despite attempts to protect the town through quarantine, eight known cases of smallpox appeared in Boston by May 27, and by mid-June, the disease was spreading at an alarming rate.

Despite Bismarck's attempts to play the role of an " honest broker " at the Congress of Berlin, Russo-German relations deteriorated following the conference.

Despite Guy Montag's attempts to break her from the spell society has on her, Mildred continues to be shallow and indifferent.

Despite some military attempts by the Spanish to retake it in the 18th century, most notably in the Great Siege of 1779 – 1783, the Rock has remained under British control ever since.

Despite his attempts at neutrality, George William was forced by Gustavus Adolphus to join the Protestant forces in 1631.

Despite victories at Dupplin Moor and Halidon Hill, in the face of tough Scottish resistance led by Sir Andrew Murray, the son of Wallace's comrade in arms, successive attempts to secure Balliol on the throne failed.

Despite a friendship with Albert Spalding, Chadwick was scornful of the attempts to have Abner Doubleday declared the inventor of baseball.

Despite his self-professed attempts to treat Jamiroquai as a band, Kay has always been at the forefront of the band.

Despite coup attempts in 1980, 1983, and 1988, Gayoom's popularity remained strong, allowing him to win three more presidential terms.

Despite her many attempts, Mei is unable to show her family Totoro's tree.

Despite attempts to silence critics, Bismarck remained a largely unpopular politician.

Despite Gorbachev's attempts to discourage Russia's electorate from voting for him, Yeltsin was popularly elected as president, handily defeating five other candidates with more than 57 percent of the vote.

Despite further attempts, the Muslims were unable to conquer Pelayo's mountain stronghold.

Despite French attempts to maintain control by encouraging sectarian divisions and isolating urban and rural areas, the revolt spread from the countryside and united Syrian Druze, Sunnis, Shiites, Allawis, and Christians.

Despite repeated attempts by family members and others to have it expunged, his conviction has never been overturned.

Despite its elegance, Montague grammar was limited by the context-dependent variability in word sense, and led to several attempts at incorporating context, such as:

Despite attempts at reorganization of the Air Board, the earlier problems failed to be completely resolved.

Despite numerous successful campaigns and raids by the Roman army over the Rhine in the years after the battle, the Romans were to make no more concerted attempts to conquer and permanently hold Germania beyond the river.

Despite white attempts to control independent black congregations, especially after the Nat Turner Uprising of 1831, a number of black congregations managed to maintain their separation as independent congregations in Baptist associations.

Despite her attempts to remain out of the public eye, she was falsely accused in the libelles of having an affair with the commander of the Garde Nationale, the marquis de La Fayette.

Despite various attempts to get her out, such as the Carnation Plot in September, Marie Antoinette refused when the plots for her escape were brought to her attention.

Despite the destruction wrought on the countryside, the city castle held out in spite of repeated attempts over twelve days to take it, and the Turks left the island unsuccessfully because of poor logistics and an epidemic that decimated their ranks.

Despite the acquisitions, the team failed to improve and finished with a record of 82 – 80, in second place behind the Los Angeles Dodgers.

Despite efforts to restore ( or at least improve ) the popularity of the Conservative party, Labour remained far ahead in the opinion polls as the 1997 election loomed, despite the economic boom that had followed the exit from recession four years earlier, and the swift fall in unemployment.

Despite Kemp's voice on minority issues, Colin Powell's support and polls that showed about 30 % of blacks identified themselves as conservatives on issues such as school prayer, school vouchers and criminal justice, the Republicans were unable to improve upon historical support levels from African-American voters.

Despite this tension, Pakistan and Sudan still engage in collaborative dialogue at OIC summits to improve political stability in the Middle East and the Islamic World ; in other words contact between the two nations still remains friendly.

Despite this, the standard of living continued to improve as local councils built new houses to let to families rehoused from outdated slums, with up to date facilities including indoor toilets, bathrooms and electric lighting now being included in the new properties.

Despite the repeal of the act, economic conditions failed to improve.

Despite having the baron de Breteuil working on her behalf, the purchase did not help improve the public's image of the queen as frivolous.

Despite the necessity of rapid reconstruction and the lack of financial means, authorities did take several measures to improve traffic flow, sanitation, and the aesthetics of the city.

Despite stating this was a response to consumer demand to improve taste and texture, there was no " new improved recipe " claim placed on New Zealand labels.

Despite the popularity of some of his work, Little failed to launch Indigenous music in the country — from the 1970s onwards, groups such as Coloured Stone, Warumpi Band, and No Fixed Address would help improve the image of the genre.

Despite continuing to improve, the Hornets failed to qualify for the playoffs for the fourth consecutive season.

Despite this setback, Dr Kik's excellent care continues to improve Virginia's mental state.

Despite these and other Community-wide efforts to improve intelligence support, the loss of resources during the 1970s limited the Community's ability to collect and produce timely intelligence and ultimately contributed to intelligence shortcomings in Iran, Afghanistan, and other strategic areas.

Despite the disagreements, popular culture grasped onto the implications in the field of applied psychology with the hope that the research could improve their lives.

Despite various efforts to improve its image, the chain was never able to move beyond its reputation there as a stodgy retailer, one that catered primarily to senior citizens and expatriate Britons.

Despite his dispatch box successes ( Smith was always more effective in the House of Commons than on platforms or at Prime Minister's Questions, though he began to improve at the latter during the final months of his life ), Tony Blair and Gordon Brown were, under Smith's leadership, restless and anxious in private that the party had adopted a " One more heave " approach and had become overly cautious in tackling the legacy of " tax and spend ".

Despite the increase in tensions due to the Second Moroccan Crisis of 1911, Bethmann Hollweg did improve relations with Britain to some extent, working with British foreign secretary Sir Edward Grey to alleviate tensions during the Balkan Crises of 1912-1913, and negotiating treaties over an eventual partition of the Portuguese colonies and the Berlin-Baghdad railway.

Despite extensive restrictions, limitations, and hardships, Decembrists believed that they could improve their situation through personal initiative.

Despite the difficulty, a prompt diagnosis of DLB is important because of the risks of sensitivity to neuroleptic drugs and because appropriate treatment of symptoms can improve life for both the person with DLB and their caregivers.

Despite a gift of £ 50, 000 in 1916, and receiving Field Marshal ’ s half pay, owning two properties in Ireland which he could not use left French again short of money, although he did not improve matters by staying often at the Hôtel de Crillon in Paris.

Despite Göring's apology after their previous dispute, it did not improve the relationship between the two men.

Despite the sale of the team, things didn't improve on the ice for the Pirates.

" Despite his party's third place showing in the election ( which was won by NDP leader Bob Rae ), Harris had managed to improve the party standing in the legislature and bring some attention to his cause.

Despite the introduction of systemwide caching that now automates this process, application level lookup tables can still improve performance for data items that rarely, if ever, change.