Despite the historical source material, Welsh has set the story in the familiar confines of present day Edinburgh, with Burke and Hare depicted as brothers who steal human organs to meet the demands of the global transplant market.

Despite its proximity to the Irish Sea, the temperature regime is similar to areas further inland, owing to the shelter provided by the Pennines to the northeast and the Welsh Mountains to the southwest.

Despite historians such as G. R. Elton, who treated the Acts as merely a triumph of Tudor efficiency, modern British, and particularly Welsh historians are more likely to investigate evidence of the damaging effects of the Acts on Welsh identity, culture, and economy.

Despite Barker's initial preference for another of the pilots, a sitcom about a Welsh gambling addict, " Prisoner and Escort " was selected.

Despite being in England, Birkenhead ( known as Penbedw, in the Welsh language ) hosted Wales ' National Eisteddfod in 1917 as well as an unofficial National Eisteddfod event in 1879.

Despite this early setback Bangor ended the 2008 – 09 season with yet more silverware as they retained the Welsh Cup by defeating Aberystwyth Town 2 – 0 in a match held at Parc Y Scarlets, Llanelli.

Despite winning the North Wales Amateur Cup three times in the 1950s, Nomads moved into local football for seven years prior to rejoining the Welsh League in 1966, twice finishing as runners-up at the start of the 1970s.

Despite some debate as to whether this honour belongs to the town team or the University side, the Welsh Rugby Union's official history " Fields of Praise: The Official History of the Welsh Rugby Union, 1881-1981 " indicates the college team as the first.

Despite playing in the English leagues, they have also been competitors in the Welsh Cup, winning it a record 23 times.

Despite the arrival of reinforcements in the form of the 53rd ( Welsh ) Division on 9 August and the 54th ( East Anglian ) Division on 10 August, any hopes the British had of a swift victory at Suvla were now gone as the Ottomans consolidated their hold on the surrounding ridges.

Despite not playing in Wales, they were invited to play in the Welsh Cup through the 70s and 80s, reaching the final in 1986 and again in 1989.

Despite the close link throughout early Welsh history, the dragon was not used exclusively as a symbol for Wales during this period, and it was used throughout Britain as a symbol of authority.

Despite repeated destructive fires, at one time involving a charitable collection in London, Builth Wells grew as a traditional Welsh market town.

Despite its name, the Welsh Football League covers only South Wales.

Despite seizure from the native Welsh, it remained within the FitzMartin family until the death of William, the 2nd Lord Martin, who died without male heir in 1326.

Despite the English language dominance of the area, the number of enrolments to Welsh language medium schools in the area continues to rise and these schools are nearing, or at, full capacity.

Despite going to the expense of setting up separate management structures for the three parts of the trainload freight sector, on 24 February 1996 all three units were sold to " North & South Railways ", a subsidiary of the American Wisconsin Central Railroad, which soon renamed the operation English, Welsh and Scottish Railway.

Despite this, he still received tremendous criticism and many felt that he was not worthy enough to inherit the Welsh number 10 shirt of Barry John, Phil Bennett and Cliff Morgan, leading Jenkins to tailor his game to the demands of the modern game.

Despite the early public criticism, Jenkins has established himself as one of the most recognisable figures in Welsh rugby and many rugby fans hold him in extremely high regard.

Despite suggestions to the contrary, the Welsh town of Porthmadog ( meaning " Madoc's Port " in English ) and the village of Tremadog (" Madoc's Town ") in the county of Gwynedd are actually named after the industrialist and Member of Parliament William Alexander Madocks, their principal developer, rather than the legendary son of Owain Gwynedd.

Despite this the club were consistently successful, achieving a long line of top ten finishes in the unofficial Welsh league, a competition they won for the first time in the 1962 / 1963 season.

Despite remaining successful at the highest level attainable by a non-regional side, Pontypridd RFC has seen a huge loss in their fan base due to the disenfranchisement of Welsh rugby supporters in the Valleys over to the appointment of Cardiff Blues as their ' regional ' team.

Despite the loss, Cleveland players took home a number of awards.

Despite this, several of the young players showed promise.

Despite the Rockies record-setting performance, the National League coaches and players didn't vote in any of Colorado's players for the NL Gold Glove award.

Despite this, the club had recruited many talented young players in the late 70s who would emerge as club greats.

Despite losing this match, Essendon's performance was good enough for its players to be awarded Brownlow Medal votes – best-on-ground was Brent Stanton ( 3 votes ), followed by Jason Johnson ( 2 votes ) and Andrew Lovett ( 1 vote ).

Despite a formal request to the AFL being denied, players wore yellow armbands for the match which resulted in the club being fined $ 20, 000.

Despite these handicaps, at war's end the club recruited many players who represented the club during its most successful era in the early 1950s.

Despite the success of these two Robinsons and other black players, the number of African-American players in Major League Baseball has declined since the 1970s.

Despite the numbers not being retired, no one has ever worn David Akers ' 2, Donovan McNabb's 5, or Randall Cunningham's 12 since those players have left the Eagles.

Despite the graphics, players were confined to back and forth motion as seen in other fighting games.

Despite its popularity the game can be deadly, leaving players ' bodies catatonic in the real world.

Despite the disdain of sousaphones held by most serious tuba players, a quality modern sousaphone is often a better choice for the high school or semi-pro player due to more stable intonation and less breath effort needed to generate tone.

Despite not having to ask the KNVB for permission to invest in new players anymore, Feyenoord kept continuing the policy for the 2012-13 season, only contracting players that were either out of contract or available for a low transfer fee.

Despite not being members of Bill Haley and His Comets, Gussak and Cedrone were trusted session players that Haley had used before.

Despite being among the best-paid players of the pre-free agency era, Mantle was a poor businessman, having made several bad investments.

Despite a childhood dream to play for the Oakland Raiders, he turned down the scholarships on the advice of his mother, who argued that football players had shorter careers.

Despite these changes, the team in regressed even further, hampered by injuries to key players.

Despite a setback in which Shooter arrives drunk to a game and ends up in a hospital, the team advances through tournament play, with contributions from unsung players, such as the pint-sized Ollie and devoutly religious Strap.

Despite this drop in status, it is still enjoyed by many players.

Despite officially retiring from the sport, he continued playing football with the veteran players of Biscay, donating the money collected from these games to charities.

Despite losing some key players, Bologna expected to be challenging strongly for promotion from Serie B in the 2005 – 06 campaign.

Despite their name, however, practice sets are used not only by beginning players but also by some advanced players when they wish to play just the chanter with other musicians, either live or in recording sessions.