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Dextromethorphan ( DXM ), a common active ingredient found in many over-the-counter cough suppressant cold medicines, is used as a recreational drug for its often euphoric dissociative effects.
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Dextromethorphan and DXM
** Others: Brompheniramine, Chlorpheniramine, Cocaine, Cyclobenzaprine, Dextromethorphan ( DXM ), Ketamine, MDPV, Nefazodone, Phencyclidine ( PCP ), Pheniramine, Sibutramine, Trazodone.
Dextromethorphan ( DXM ) may be modestly effective in decreasing cough in adults with viral upper respiratory infections.
* Dextromethorphan ( DXM ), the active ingredient of cough medications like Robitussin DM, is abused for its effects which are similar to ketamine and PCP.
Dextromethorphan and common
Dextromethorphan, a common antitussive often found in cough medicines, has been shown to cause vacuolization in rats ' brains when administered at doses of 75 mg / kg.
Dextromethorphan and ingredient
Dextromethorphan and found
Dextromethorphan and cough
Dextromethorphan has powerful dissociative properties when administered in doses well above those considered therapeutic for cough suppression.
Robitussin contains an expectorant ( Guaifenesin ); Robitussin DM adds a cough suppressant ( Dextromethorphan ) to the expectorant ( Guaifenesin ); Robitussin CF is a cold formula that adds an expectorant and a nasal decongestant ; there is a nighttime-relief formula that uses a different cough suppressant, and there is a formula with codeine, available by prescription only.
Dextromethorphan and is
Dextromethorphan is still excluded from the CSA ( as of 2010 ); however, officials have warned that it could still be added if increased abuse warrants its scheduling.
Dextromethorphan and drug
It can also be a side effect of the anti-epileptic drugs Phenytoin and Zonisamide, and the anti-convulsant drug Lamotrigine, as well as the hypnotic drug Zolpidem and the dissociative drugs Ketamine and Dextromethorphan.
Dextromethorphan and .
Dextromethorphan has been noted to slow the development of tolerance to opioids and exert additional analgesia by acting upon the NMDA receptors ; some analgesics such as methadone and ketobemidone and perhaps piritramide have intrinsic NMDA action.
Dextromethorphan was excluded from the Controlled Substances Act ( CSA ) of 1970 and was specifically excluded from the Single Convention on Narcotic Drugs.
DXM and ),
NMDA antagonists such as dextromethorphan ( DXM ), ketamine ( a dissociative anaesthetic, also M. O. A +.
* over-the-counter medications ( in some countries they might be prescription drugs ): dextromethorphan ( DXM, dissociative ), codeine ( opiate, often with paracetamol to discourage recreational use ), some deliriants ( benzydamine, dimenhydrinate and diphenhydramine ) and stimulants ( ephedrine and pseudoephedrine )
There are several types of drugs that can initiate an OBE, primarily the dissociative hallucinogens such as ketamine, dextromethorphan ( DM or DXM ), and phencyclidine ( PCP ).
The development of a potentially life-threatening serotonin syndrome ( also more recently classified as " serotonin toxicity ") may occur with venlafaxine treatment, particularly with concomitant use of serotonergic drugs, including but not limited to SSRI and SNRIs, many hallucinogens such as tryptamines and phenethylamines ( LSD / LSA, DMT, MDMA, MDPV, mescaline for example ), dextromethorphan ( DXM )/ dextrorphan ( DXO ), tramadol, tapentadol, meperidine / pethidine and triptans and with drugs that impair metabolism of serotonin ( including MAOIs ).
DXM and found
The same researchers also found no evidence of neurotoxic changes in retrosplenial or cingulate cortices of male rats orally administered up to 400 mg /( kg day ) DXM HBr or female rats orally administered 120 mg /( kg day ) DXM HBr, both for 30 days.
DXM and medicines
Frequently, customers buying larger-than-usual doses of medicines ( such as DXM, promethazine, codeine or Gee's linctus ) will be queried, due to the possibility of abuse.
DXM and is
Bad trip ( or psychedelic crisis ) is a disturbing experience sometimes associated with use of a psychedelic drug such as LSD, Salvinorin A, DXM, mescaline, psilocybin, cannabis, DMT and sometimes even other drugs including alcohol and MDMA.
DXM and used
Antipsychotics are not effective against dissociatives such as PCP, DXM and Ketamine, and should not be used if these drugs are involved.
DXM and drug
Because of its chemical similarity to levomethorphan, DXM could also be treated as a Schedule II drug under the Federal Analog Act.
DXM and for
Some states and store chains have implemented restrictions, such as requiring signatures for DXM sale, limiting quantities allowable for purchase, and requiring that purchasers be over the age of majority in their state.
DXM and .
Dissociatives such as ketamine, DXM, and PCP do so as well via antagonism of the NMDA glutamate receptors.
Some " primitive religions " encourage spiritual experiences through the ingestion of psychoactive drugs such as alcohol and opiates, but more commonly with entheogenic plants and substances such as cannabis, salvia divinorum, psilocybin mushrooms, peyote, DXM, ayahuasca, or datura.
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