Her contributions are mainly on the roles of antibodies directed against ion channel at the nerve-muscle junction in the pathogenesis of above mentioned diseases.

Her movie career included a bit part in It Happened One Night ( 1934 ) and roles in Outlaw Women ( 1952 ), Glen or Glenda ( 1953 ), Body Beautiful ( 1953 ), The Blue Gardenia ( 1953 ), Count the Hours ( 1953 ), Mesa of Lost Women ( 1953 ), College Capers ( 1954 ), Jail Bait ( 1954 ), The Raid ( 1954 ), This Is My Love ( 1954 ), The Opposite Sex ( 1956 ), The Ironbound Vampire ( 1997 ), and Dimensions in Fear ( 1998 ).

Her almost 60-year career crossed most media frontiers with both supporting and leading roles, but she may be best-remembered for playing the sardonic but engaging title character, a high school teacher, on Our Miss Brooks, and as the Rydell High School principal in the films Grease and Grease 2.

Her Stage Door portrayal of a fast-talking, witty supporting character, gained Arden considerable notice and was to be a template for many of Arden's future roles.

Her many memorable screen roles include a supporting role as Joan Crawford's wise-cracking friend in Mildred Pierce ( 1945 ) for which she received an Academy Award nomination as Best Supporting Actress, and James Stewart's wistful secretary in Otto Preminger's then-explicit murder mystery, Anatomy of a Murder ( 1959 ).

Her debut at Teatro alla Scala took place in 1842 as " Neocle " in the Italian version of Le siège de Corinthe, which was followed by roles in operas by Marliani, Donizetti ( as " Maffio Orsini "), Salvi and Pacini.

Her subsequent roles in the 1990s and 2000s included Open Your Eyes ( 1997 ), The Hi-Lo Country ( 1999 ), The Girl of Your Dreams ( 2000 ) and Woman on Top ( 2000 ).

Her other television roles include recurring appearances as Marelene on Dharma & Greg, and Penny in two episodes of Dead Like Me.

Her one scene role as pregnant checkout girl Nancy in 1991's City Slickers earned her " more attention than all previous roles combined ," and taught her that " that it's far better to have small parts in big movies that everyone sees.

Her other roles include parts in Barry Levinson's Toys and James L. Brooks ' As Good as It Gets.

Her best known film roles were " Susanne Wallner " in Wolfgang Staudte's film Die Mörder sind unter uns ( The Murderers Are Among Us ), the first film released after the Second World War in East Germany and produced by DEFA ); and in 1950, " Marina " in Die Sünderin ( The Sinner ), in which she performed a brief nude scene, the first in German film history, causing a scandal.

Her other notable film roles include Sara in Runaway Train in 1985, Helen McCaffrey in the thriller Backdraft in 1991, her portrayal of the chillingly twisted nanny Peyton Flanders in the popular 1992 thriller The Hand That Rocks the Cradle and as Wendy Torrance in Stephen King's 1997 television adaptation of The Shining.

Her best known roles include starring as Jacy in The Last Picture Show, as Betsy in Taxi Driver, as Madeleine Spencer in Psych, as Maddie Hayes in Moonlighting, as Cybill Sheridan in Cybill, and as Phyllis Kroll in The L Word.

Her friend Miriam Cooper helped Lombard land small roles in her husband Raoul Walsh's films.

Hawn is known for her roles in Rowan & Martin's Laugh-In, Private Benjamin, Foul Play, Shampoo, Overboard, Bird on a Wire, Death Becomes Her, The First Wives Club, and Cactus Flower, for which she won the 1969 Academy Award for Best Supporting Actress.

With increasing interest in the war in Europe, the film performed well at the box office, but Shearer made errors in judgment, passing up roles in the highly successful films Now, Voyager and Mrs. Miniver, in order to star in We Were Dancing and Her Cardboard Lover ( 1942 ), which both failed at the box office.

Although Caine also took better roles, including a BAFTA-winning turn in Educating Rita ( 1983 ), and an Oscar-winning one in Hannah and Her Sisters ( 1986 ) and a Golden Globe-nominated one in Dirty Rotten Scoundrels ( 1988 ), he continued to appear in notorious duds like the thinly veiled skin flick Blame It on Rio, the Dick Clement and Ian Le Frenais comedy Water and the critical-commercial flop Jaws: The Revenge ( 1987 ) ( in which he had mixed feelings about the production and the final cut ) and Bullseye!

Garbo had successfully made the transition to talkies and after three less profitable films, Romance ( 1930 ), Inspiration ( 1931 ), and Susan Lenox ( Her Fall and Rise ) ( 1931 ), she performed two of her most famous roles.

Her final years were marred by a long period of ill health, but she continued acting until shortly before her death from breast cancer, with more than 100 films, television and theater roles to her credit.

Her image was considered with more care ; although she continued to play character roles, she was often filmed in close-ups that emphasized her distinctive eyes.

Her film choices were often unconventional ; she sought roles as manipulators and killers in an era when actresses usually preferred to play sympathetic characters, and she excelled in them.

* Her notoriety intersected with the criminal obsessions and camp sensibilities of filmmaker John Waters, who has used Hearst in numerous small roles in films including Cry-Baby, Serial Mom, Pecker, Cecil B. DeMented, and A Dirty Shame.

Her other film roles included the Queen of Hearts in Alice in Wonderland ( 1972 ), Livia in the abortively-attempted I, Claudius ( 1937 ), Miss Milchrest in Murder at the Gallop ( 1963 ).

Rossellini is noted for her 14-year tenure as a Lancôme model, and for her roles in films such as Blue Velvet and Death Becomes Her.

Some other notable film roles include her work in Cousins, Death Becomes Her, Immortal Beloved, and Fearless.

Her eyes were glazed as if she didn't hear or even see him.

Her blond hair was frowzy, her dress torn in several places, and her shoes were so completely worn out that they were practically no protection.

Her legs were the full, sexy kind, full bodied like a rare wine and just as tantalizing to the appetite ; ;

Her glance swung past the trailer where the two drivers were standing.

Her long thin arms moved in a slow rhythmical gesture over the family possessions which were placed in front of her.

Her quarters were on the right as you walked into the building, and her small front room was clogged with heavy furniture -- a big, round, oak dining table and chairs, a buffet, with a row of unclaimed letters inserted between the mirror and its frame.

Her thoughts were not discrete.

Her eyebrows were definite and heavy and formed two lines moving upward toward a high forehead and a great head of brown hair that fell to her shoulders.

Her services to the School for many years were of a very high character, and I have often thought that one of the buildings should be named for her ''.

Her eyes were bright with anticipation.

Her `` Rockabye Your Baby '' was as good as it can be done, and her really personal songs, like `` The Man That Got Away '' were deeply moving.

Her hesitation was only momentary and she hoped he didn't notice it, as she settled herself, asked quickly how Miss Jenny and the babies were getting on.

Her nose was higher of bridge, her complexion so pale as to be quite susceptible to sunburn, and the fish and vegetable diet of her forebears had given her teeth that were white and regular and strong.

Her bright eyes were twinkling.

Her hair never seemed to be in place and her skirts were never quite the correct length.

Her eyes were wild.

Her dark cool caresses were sweeter than any woman's ; ;

Her eyes were smiling, too, but so sadly, and there was tiredness and infinite wisdom in them.

Her extendibles were diverted, connected or augmented and the final, delicate-beyond-description brain taps were completed while Helva remained anesthetically unaware of the proceedings.

Her book titles, changed by American publishers, for example Ten Little Niggers to Ten Little Indians, were kept the same across the Atlantic, after bushels of fan mail.

Her two children by Philip II, Philip, count of Clermont ( died 1234 ), and Mary, who married Philip I of Namur, were legitimized by the pope in 1201 at the request of the king.

Her remaining children were raised between her, Livia Drusilla and Germanicus ’ mother Antonia Minor.

Her reputed last words, uttered as the assassin was about to strike, were " Smite my womb ", the implication here being she wished to be destroyed first in that part of her body that had given birth to so " abominable a son.