However, in recent decades, for what doubtless are multiple reasons, an unannounced but nonetheless readily observable shift has occurred in both facets of national activity.

However, in the context of legal and civic policy, these controversies are less than novel.

However, despite the insight of many of his observations, his own conclusions are open to suspicion because of his failure to employ at all times the correct research methods.

However, there are still several types of calls that necessitate the use of telephone operators.

However, he states unequivocally `` the scandals in business are far less significant than the scandals in labor ''.

However, few are taxed, and the owners and location of most boats are unknown to the assessors on the date of assessment of town valuations.

However, the surface temperature gradient can produce erroneous vapor-pressure measurements for the bulk liquid helium unless precautions are taken to isolate the tube ( which passes through the surface to the vapor pressure bulb ) from the liquid helium surface.

However, if their United States income is not subject to the withholding of tax on wages, their returns are due June 15, 1962, if they use a calendar year, or the 15th day of the 6th month after the close of their fiscal year.

However, the aircraft which we have today are tied to large, `` soft '' airfields.

However, some formulas are used more than others.

However, there is also much to be gained by making use of the abilities of the local people who are available and interested in recreation.

However, there are photographs of suspended drops of cyclohexanol phthalate ( viscosity 155 poises ) suspended in corn syrup of 71 poises in a paper by Mason and Bartok.

However, any oxygen nonequivalence would shorten either the already extremely short Af interlayer distance of 2.55 A or the non-hydrogen-bonded Af interlayer interactions which are already quite short at 2.58 Aj.

However, as so many of the records are not certainly based on newborn snakes, these data must be taken tentatively ; ;

However, if these procedures are applied more often, conditioned emotional responses are temporarily abolished.

However, it cannot be presumed, informal though the structure of the population seems, that there are not well-defined roles within the system.

However, the differences in procedure are fundamental.

However, the regionally differentiated results, which appear below in tables, are interesting evidence of the problems of developing self-government under even the most favorable circumstances.

However, if Federal funds are used, it would be entirely appropriate to train workers for jobs which could be obtained elsewhere as well as for jobs in the area of chronic unemployment.

However, it is not known to either the union or the public precisely how much of a cost increase is caused by a given change in the basic wage rate, although the companies are presumed to have reliable estimates of this magnitude.

However, there are relatively few such political constituencies, and, as has been pointed out, there is seldom a clear-cut distinction between the educational interests of one social class and those of another.

However, modesty and triviality are different qualities.

`` However, evidence that the Axis powers are making significant preparations indicative of such an intention is being reported with increasing frequency from a variety of sources.

However the game is mission orientated and involves setting up a futuristic base and carrying out missions which involve mining minerals, developing relationships, harvesting resources to prevent running out of oxygen and power, collecting food, and fighting back alien attacks.

" However, this was repealed by the county commission in 1993, after " racially orientated redistricting " led to a change in government.

However it was later revealed that many who signed the petition were from outside of Bromsgrove and that the campaign had been party politically orientated.

However, another company would launch their own free-to-air movie channel just ahead of Sit-Up's in the 333 slot ; True Movies was also female orientated with an emphasis on true stories.

However, panic had spread to the family orientated and peaceful town folk, who had now started to flee what was an out of control town.

However, in November 2008 Laycock's Sunday night programme changed format to a more swing orientated playlist.

However, as we have seen, reducing a tachyon's energy increases its speed, so that the single hyperbola formed is of two oppositely charged tachyons with opposite momenta ( same magnitude, opposite sign ) which annihilate each other when they simultaneously reach infinite speed at the same place in space.

However, each piece has two oppositely sloping tapers mating with the two adjoining pieces so that the piece cannot be removed in either direction.

However, the situation often arises in the campaign world that oppositely aligned characters will side with each other briefly if a threat looms over all, and also both good and evil characters will infiltrate each others ' organizations for purposes of espionage.

However, despite possessing many other G-protein coupled receptors ( GPCRs ), the fully sequenced genome of Amphimedon queenslandica, a demosponge larvae, lacks one vital visual component: a gene for a light-sensitive opsin pigment – which is essential for vision in other animals – suggesting that the sponge ’ s unique eyes might have evolved a completely novel light-detection mechanism.

However, large proteins must have a specific signaling sequence to be transported across the outer membrane, so the protein composition of this space is different from the protein composition of the cytosol.

However, once Ca < sup > 2 +</ sup > signaling in the mitochondria passes a certain threshold, it stimulates the intrinsic pathway of apoptosis in part by collapsing the mitochondrial membrane potential required for metabolism.

However, they also require a small membrane potential for the kinetics of ATP synthesis.

However, this membrane may be tightly folded into cylindrical sheets called thylakoids, or bunched up into round vesicles called intracytoplasmic membranes.

However, intrinsic membrane proteins remain challenging to crystallize because they require detergents or other means to solubilize them in isolation, and such detergents often interfere with crystallization.

However, some species, including the great white shark ( Carcharodon carcharias ), do not have this membrane, but instead roll their eyes backwards to protect them when striking prey.

However, the mechanism of the secretion of intra-vesicular contents out of the cell is very different from the incorporation of ion channels, signaling molecules, or receptors at the cell membrane.

However, many cyanobacter species have folds on its external membrane which function in photosynthesis.

However, at the same time such invasive setup reduces the life of the cell and causes a leak of substances across the cell membrane.

However, membrane pumps and ion channels also contain numerous charged and polar residues within the generally non-polar transmembrane segments.

However, the electron transport complexes remain on the membrane.

However, some bacteria do not use typical caveolae but only caveolin-rich areas of the plasma membrane.

However, under special circumstances such as hypothermia, hyperbaric oxygenation, apneic oxygenation ( see below ), or extracorporeal membrane oxygenation, much longer periods of apnea may be tolerated without severe consequences.

However, for each mechanism the epithelial cells ' " niche " can be delicately unique with different membrane receptor profiles and basement membrane thickness from specific branching area to area, so as to regulate cell growth or differentiation sub-locally.

However, the NMDA receptor cation channel is blocked by Mg < sup > 2 +</ sup > at resting membrane potential.

However, the development of models to predict the mechanisms of membrane fusion will assist in the scientific understanding of how to target the process with antiviral drugs.

However, the basilar membrane is in fact permeable to perilymph, thus the second border between endolymph and perilymph occurs at the reticular lamina.

However, at least one fusion-inhibiting antibody was found to bind closer to the top of hemagglutinin, and is thought to work by cross-linking the heads together, the opening of which is thought to be the first step in the membrane fusion process.

However, since the Mg < sup > 2 +</ sup > is charged and is bound within the membrane's electric field, depolarization of the membrane potential above threshold can dislodge the magnesium, allowing current flow through the NMDAR channel.

However, some of the molecules embedded in the membrane are capable either of actively transporting ions from one side of the membrane to the other or of providing channels through which they can move.

However, it also takes into consideration the relative permeability of the plasma membrane to each ion in question.

However, such dialyzers require newer dialysis machines and high-quality dialysis solution to control the rate of fluid removal properly and to prevent backflow of dialysis solution impurities into the patient through the membrane.