# Targeting exon skipped transcripts: If the problem in the gene lies in aberrant splicing post-transcription, siRNA can be designed to target the unnatural exon-exon interface arising as a result of such alternative splicing.

If the circumstances are faced frankly it is not reasonable to expect this to be true.

If his dancers are sometimes made to look as if they might be creatures from Mars, this is consistent with his intention of placing them in the orbit of another world, a world in which they are freed of their pedestrian identities.

If a work is divided into several large segments, a last-minute drawing of random numbers may determine the order of the segments for any particular performance.

If they avoid the use of the pungent, outlawed four-letter word it is because it is taboo ; ;

If Wilhelm Reich is the Moses who has led them out of the Egypt of sexual slavery, Dylan Thomas is the poet who offers them the Dionysian dialectic of justification for their indulgence in liquor, marijuana, sex, and jazz.

If he is the child of nothingness, if he is the predestined victim of an age of atomic wars, then he will consult only his own organic needs and go beyond good and evil.

If it is an honest feeling, then why should she not yield to it??

If he thus achieves a lyrical, dreamlike, drugged intensity, he pays the price for his indulgence by producing work -- Allen Ginsberg's `` Howl '' is a striking example of this tendency -- that is disoriented, Dionysian but without depth and without Apollonian control.

If love reflects the nature of man, as Ortega Y Gasset believes, if the person in love betrays decisively what he is by his behavior in love, then the writers of the beat generation are creating a new literary genre.

If he is good, he may not be legal ; ;

If the man on the sidewalk is surprised at this question, it has served as an exclamation.

If the existent form is to be retained new factors that reinforce it must be introduced into the situation.

If we remove ourselves for a moment from our time and our infatuation with mental disease, isn't there something absurd about a hero in a novel who is defeated by his infantile neurosis??

If many of the characters in contemporary novels appear to be the bloodless relations of characters in a case history it is because the novelist is often forgetful today that those things that we call character manifest themselves in surface behavior, that the ego is still the executive agency of personality, and that all we know of personality must be discerned through the ego.

If he is a traditionalist, he is an eclectic traditionalist.

If our sincerity is granted, and it is granted, the discrepancy can only be explained by the fact that we have come to believe hearsay and legend about ourselves in preference to an understanding gained by earnest self-examination.

If to be innocent is to be helpless, then I had been -- as are we all -- helpless at the start.

If that's done, the house can be designed and oriented for best operation, and this can mean savings both in the size of equipment and in the cost of the house itself.

If the house you plan to buy or build won't have big overhangs, you can still do a fair job of keeping the sun off walls and windows with properly designed trellises, fences and awnings.

If it was designed to put me on the spot, it would have to have been written before Peralta ever called me in on the case ''.

If products designed for the new standard can receive, read, view or play older standards or formats, then the product is said to be backward-compatible ; examples of such a standard include data formats and communication protocols.

If integration via the bus is achieved, the data warehouse, through its two data marts, will not only be able to deliver the specific information that the individual data marts are designed to do, in this example either " Sales " or " Production " information, but can deliver integrated Sales-Production information, which, often, is of critical business value.

If they express much more than this, they are usually considered to be a hardware description language such as Verilog, VHDL, or any one of several specific languages designed for input to simulators.

If a cryptographic hash function is well designed, it is computationally infeasible to reverse the function to recover a plaintext password.

Many of his stories, such as Gulf, If This Goes On —, and Stranger in a Strange Land, depend strongly on the premise, related to the well-known Sapir – Whorf hypothesis, that by using a correctly designed language, one can change or improve oneself mentally, or even realize untapped potential ( as in the case of Joe Green in Gulf ).

If they had any significant level of non-organic parts then something as simple as an x-ray scan would show them not to be human ( unless their creators designed the non-organic parts to have almost exactly the same structure and density as the organic components they were replacing, which would be both infeasible and highly improbable but not completely out of the question ).

If the coil is designed to be energized with alternating current ( AC ), a small copper " shading ring " can be crimped to the end of the solenoid, creating a small out-of-phase current which increases the minimum pull on the armature during the AC cycle.

If the instrument is designed to measure the spectrum in absolute units rather than relative units, then it is typically called a spectrophotometer.

If error correction facilities are needed at the network interface level, an application may use the Transmission Control Protocol ( TCP ) or Stream Control Transmission Protocol ( SCTP ) which are designed for this purpose.

If a machine that is not designed to support Wake-on-LAN is left powered down after power failure, it may be possible to set the BIOS to start it up automatically on restoration of power, so that it is never left in an unresponsive state.

If searching for microsatellite markers in specific regions of a genome, for example within a particular exon of a gene, primers can be designed manually.

If the palace was designed for Lucullus, then it may have only been in use for a few years, for the Roman historian Suetonius records that Lucullus was executed by the delusional emperor Domitian in or shortly after AD 93.

If the device has been designed to power a shaft as with an industrial generator or a turboprop, the exit pressure will be as close to the entry pressure as possible.

If I < sub > static </ sub > is source code designed to run inside said interpreter, then partial evaluation of the interpreter with respect to this data / program produces prog *, a version of the interpreter that only runs that source code, is written in the implementation language of the interpreter, does not require the source code to be resupplied, and runs faster than the original combination of the interpreter and the source.

If properly designed, these scalable exercises can be used for small groups ( 12 to 20 people ) as well as very large events ( 600 people or 100 tables ).

If a forward canard is used for pitch control, rather than an aft tail, the canard is designed to meet the airflow at a slightly greater angle of attack than the wing.

If an aft tail is used, the wing is designed to stall before the tail.

If headphones were designed to have a flat response, then they would sound much too ' bright ' when used to listen to stereo recordings and for this reason, most headphones are designed to have a notch around 5 kHz.

If headphones were designed to be flat, with a choice of equalisations available in headphone amplifiers, then headphone listening could be a more controlled experience, whether in binaural or stereo mode.

If the camera is fitted within a frame, this ' rig ' can be designed to rotate horizontally and vertically and to change the picture format from portrait to landscape by rotating the camera.