In 1250 or 1251, Mindaugas agreed to receive baptism and relinquish control over some lands in western Lithuania, in return for an acknowledgment by Pope Innocent IV as king.

On 19 June 1250, following the canonisation of Malcolm's wife Margaret by Pope Innocent IV, Margaret's remains were disinterred and placed in a reliquary.

In 1250, he travelled to the papal court where one of the cardinals read his complaints at an audience with Innocent IV.

Though he was backed by Pope Innocent IV and anti-king William of Holland, he could not prevail against the mighty Přemyslid king Wenceslaus I of Bohemia and his son Ottokar II, who upon Herman's death in 1250 occupied the Babenberg lands.

In 1250 she was canonised by Pope Innocent IV, and her remains were reinterred in a shrine at Dunfermline Abbey.

Saint Margaret was canonised in 1250 by Pope Innocent IV in recognition of her personal holiness, fidelity to the Church, work for religious reform, and charity.

The deposition of Emperor Frederick II of Hohenstaufen by Pope Innocent IV in 1245 created a grave crisis for the Holy Roman Empire, as in the following decades several nobles were elected as Rex Romanorum and Emperor-to-be, none of whom were able to gain actual governing power upon the Emperor's death in 1250.

Shortly after this decision the hitherto friendly relations between Pope Innocent IV and the archbishop ceased, and in April 1250, the Apostolic legation in Germany was committed to Pierre de Colmieu, Bishop of Albano.

A November 11, 1250 letter of king Béla IV of Hungary to Pope Innocent IV says that Tatars imposed tribute onto the countries neighboring with his kingdom: " que ex parte Orientis cum regno nostro conterminantur, sicut Ruscia, Cumania, Brodnici, Bulgaria ".

Following the collapse of the Kassite dynasty, Mesopotamian documents make no mention of Dilmun with the exception of Assyrian inscriptions dated to 1250 BC which proclaimed the Assyrian king to be king of Dilmun and Meluhha, as well as Lower Sea and Upper Sea.

Notable structures bordering René Lévesque Boulevard include, from west to east, the Montreal Children's Hospital, the Canadian Centre for Architecture, the Cité du commerce électronique, 1250 René-Lévesque, Tour CIBC, Mary, Queen of the World Cathedral, the Queen Elizabeth Hotel, Place Ville-Marie, Central Station, Tour Telus, St. Patrick's Basilica, Complexe Desjardins, Complexe Guy-Favreau, Hydro-Québec Building, UQAM and the Maison Radio-Canada.

Theresa of Portugal ( Coimbra, October 4, 1178 – Lorvão, June 18, 1250 ;) was Queen of Léon as the first wife of King Alfonso IX of León.

* St. Margaret the Queen, Buxted church, built in 1250

* Margaret of Burgundy, Queen of Sicily ( 1250 – 1308 ), daughter of Odo of Burgundy, wife of Charles I of Naples and Sicily

However, Margaret wished to be a nun ( and was later canonized ); Charles instead married ( on 18 November 1268 ), Margaret, Countess of Tonnerre ( 1250 – 4 September 1308, Tonnerre ), the daughter of Eudes of Burgundy.

* Saint Margaret of Scotland was buried here in 1093 ; on 19 June 1250 following her Canonization her remains were disinterred and placed in a reliquary at the high altar.

* Margaret, Countess of Tonnerre ( 1250 – 1308 ), married king Charles I of Naples

* Vardan Aygektsi ( died 1250 ), Armenian priest and fabulist

After the death of Frederick II in 1250, the German kingdom was divided between his son Conrad IV ( died 1254 ) and the anti-king, William of Holland ( died 1256 ).

* Heinrich Frauenlob, poet, born 1250 / 60, died November 29, 1318 in Mainz

* Arnulf of Leuven ( died 1250 ), medieval abbot

* Saint Dominguito del Val ( died 1250 ) child martyr

Saint Dominguito del Val ( died c. 1250 ) was a choirboy and the alleged victim of a ritual murder by Jews in Zaragoza ( also known as Saragossa ).

When King Eric XI died in 1250, Valdemar was elected king.

Ingrid Ylva Sunesdotter of Bjelbo ( born c. 1180s, died c. 1250 – 1255 ), was a Swedish noblewoman, the wife of Magnus Minnesköld of Bjälbo and the mother of regent Birger Jarl.

When Frederick died in 1250, his dominion was inherited by his son, Conrad.

* Jean Guillaume de Beaumont ( died 1257 ), Marshal of France in 1250

Geoffrey de Turville ( died 1250 ) Lord Chancellor of Ireland, was born in Turville.

The League was dissolved in 1250 once Frederick died.

# John Tristan ( 1250 – 3 August 1270 ), born in Egypt on his father's first Crusade and died in Tunisia on his second

* Jeanne ( 1200 – 1223 ), married Raoul II of Lusignan ( died 1250 ), Seigneur d ' Issoudun and Count of Eu.

* Laure, married in 1250 to Jean de Dampierre ( died 1258 ), viscount of Troyes, and then to Guillaume de Vergy, lord of Mirebeau and Autrey

She was firstly married in 1250 to Henry I of Cyprus, who died in 1253.

Godfrey of Fontaines ( born sometime before 1250, died between on October 29 in 1306 or 1309 ).

In 1250, when the Ayyubid sultan as-Salih Ayyub died, the Mamluks he had owned as slaves murdered his son and heir Turanshah, and Shajar al-Durr the widow of as-Salih became the Sultana of Egypt.

The ribbed vault over the entrance passage, the murder hole and the massive portcullis at either end of the gatehouse are later insertions started by Hugh de Lacey who died in 1248 and did not live to see its completion in around 1250 A. D.

The next ruler of Austria was Gertrude's second husband, Hermann VI, Margrave of Baden, who died in 1250, leaving Austria and Styria without a ruler again.

* Herman VI, Margrave of Baden ( died 1250 ), second husband of Gertrude of Babenberg, the daughter of the late Henry of Modling, the elder brother of the now late Duke Frederick.

Gertrude was suspected of poisoning Herman when he died on 4 October 1250.

* Aubrey de Troisfontaines ( died c. 1250 ), French chronicler of the 13th century

Some writers, such as James-Charles Noonan, hold that, in the case of cardinals, the form used for signatures should be used also when referring to them, even in English ; and this is the usual but not the only way of referring to cardinals in Latin .< ref > An Internet search will uncover some hundreds of examples of " Cardinalis Ioannes < surname >", examples modern and centuries-old ( such as this from 1620 ), and the phrase " dominus cardinalis Petrus Caputius " is found in a document of 1250.

Early sources: river Ilfing ( 890 ), Castrum de Elbingo quod a nomine fluminis Elbingum appellavit ( 1237 — Peter of Dusburg, Chronicon terrae Prussiae ), in Elbingo ( 1239 ), in Elbing ( 1242 ), in Elbinge ... fluvium Elbinc ( 1246, city charter ), de Elbingo ( 1250 ), in Elbyngo ( 1258 ), vitra Elbingum ( 1263 ), Elvingo ( 1293 ), in Elbingo ( 1300 ), in Elvingo ( 1389 ), czum Elbinge ( 1392 ), czu Elbing ( 1403 ), Elwing ( 1410 ), czum Elwinge ( 1412 ), Elbing ( 1414 – 1438 ), Elbyang ( before 1454 ), Elbing ( 1508 ), ku Elbiągowi ( 1634 ), w Elblągu ( 1661 ), w Elblągu ( 1661 ).

* The work of the Rosh, Rabbi Asher ben Jehiel ( 1250 ?/ 1259 ?– 1328 ), an abstract of the Talmud, concisely stating the final halakhic decision and quoting later authorities, notably Alfasi, Maimonides, and the Tosafists.

However, modern Homo sapiens have a brain volume slightly smaller ( 1250 cm < sup > 3 </ sup >) than Neanderthals, women have a brain slightly smaller than men and the Flores hominids ( Homo floresiensis ), nicknamed hobbits, had a cranial capacity of about 380 cm < sup > 3 </ sup > ( considered small for a chimpanzee ), about a third of the Homo erectus average.