The earliest painted Portrait of the Artist Holding a Thistle ( Albrecht Dürer ) | Self-Portrait ( 1493 ) by Albrecht Dürer, oil, originally on vellum ( Louvre, Paris )

It was discovered by the humanist Conrad Celtis in 1493 / 94 in the Cloister of St. Emmeram in Regensburg and formed the first edition ( illustrated by Albrecht Dürer ).

He had formed an alliance with Spain and the Holy Roman Emperor Maximilian I, but in 1493, when they went to war with France, England was dragged into the conflict.

In 1493 he went to Paris and then to Italy, studying canon and civil law, patristics and Greek.

Organists who worked at the cathedral include Henry Bredemers ( 1493 – 1501 ), who went on to become a teacher to Philip the Handsome's children, and the renowned English composer John Bull ( 1615 – 1628 ), who fled to Flanders from his home country escaping justice.

A view of Strasbourg Cathedral from Hartmann Schedel's Weltchronik ( Nuremberg 1493 ).

After two years, he gave up his appointment to pursue his studies at Leipzig, where, as rector, he received the support of the professor of classics, Peter Mosellanus ( 1493 – 1525 ), a celebrated humanist of the time, with whom he had already been in correspondence.

In 1484 Antonio took up his residence in Rome, where he executed the tomb of Pope Sixtus IV, now in the Museum of St. Peter's ( finished in 1493 ), a composition in which he again manifested the quality of exaggeration in the anatomical features of the figures.

In 1493 Poynings was acting as deputy or governor of Calais ; in July he was sent with Warham on a mission to Archduke Philip to gain Perkin Warbeck's expulsion from Burgundy, where he had been welcomed by the dowager duchess Margaret ; the envoys obtained from Philip a promise that he would abstain not aid Warbeck, but the duke asserted that he could not control the actions of the duchess, who was the real ruler of the country.

On 4 November 1493, Christopher Columbus's second voyage unloaded here, where Columbus would have met Amerindians.

He held land on the Welsh border, notably in Worcestershire where he became a magistrate ( JP ) in 1493.

Born in London, he entered Winchester School as a scholar in 1487, and proceeded in 1491 to New College, Oxford, where he became Fellow in 1493.

The St Mark's Clock was assembled in 1493, by the famous clockmaker Gian Carlo Rainieri from Reggio Emilia, where his father Gian Paolo Rainieri had already constructed another famous device in 1481.

* François Rabelais ( 1493 – 1553 ) was a monk at Fontenay-le-Comte, where he studied Greek and Latin, as well as science, philology, and law.

When word arrived in 1493 that his brother had succeeded, Bartholomew returned to Spain, where he missed Christopher, who had already left on the second voyage of his four to the " New World ".

From 1493, other locations would also host the sejms, most prominently Kraków, where 29 sessions were held.

The St Mark's Clock was assembled in 1493, by the famous clockmaker Gian Carlo Rainieri from Reggio Emilia, where his father Gian Paolo Rainieri had already constructed another famous device in 1481.

The Krbava field and Udbina itself was the location of a medieval bishopric and the Battle of Krbava field of September 9, 1493, where the Croats under ban Emerik Derenčin ( Hungarian: Imre Derencsényi ) and the Frankopans suffered one of the major defeats at the hands of the Ottoman Empire.

Conversely, Elijah Delmedigo ( c. 1458 – c. 1493 ), in his Bechinat ha-Dat endeavored to show that the Zohar could not be attributed to Shimon bar Yochai, arguing that if it were his work, the Zohar would have been mentioned by the Talmud, as has been the case with other works of the Talmudic period, that had bar Yochai known by divine revelation the hidden meaning of the precepts, his decisions on Jewish law from the Talmudic period would have been adopted by the Talmud, that it would not contain the names of rabbis who lived at a later period than that of Simeon ; and that if the Kabbalah was a revealed doctrine, there would have been no divergence of opinion among the Kabbalists concerning the mystic interpretation of the precepts.

As Columbus would only return from his voyage in 1493, this globe does not show the New World yet.

Later, the 1481 Papal Bull Aeterni regis granted all lands south of the Canary Islands to the Portuguese Empire, while in May 1493 the Aragonese-born Pope Alexander VI decreed in the Bull Inter caetera that all lands west of a meridian only 100 leagues west of the Cape Verde Islands should belong to the Spanish Empire while new lands discovered east of that line would belong to Portugal.

His reign is generally dated from 1506 to 1493 BC, but a minority of scholars, who feel that astrological observations used to calculate the timeline of ancient Egyptian records and thus the reign of Thutmose I, were taken from the city of Memphis rather than from Thebes, would date his reign from 1526 BC to 1513 BC.

Accordingly, Thutmose is usually given a reign from 1506 BC to 1493 BC in the low chronology, but a minority of scholars would date him from 1526 BC to 1513 BC

It is still possible to estimate when Thutmose II's reign would have begun by means of a heliacal rise of Sothis in Amenhotep I's reign, which would give him a reign from 1493 BC to 1479 BC, although uncertainty about how to interpret the rise also permits a date from 1513 BC to 1499 BC, and uncertainty about how long Thutmose I ruled could also potentially place his reign several years earlier still.

The Niña and Pinta sighted and rejoined one another 6 January 1493, and, after a furious argument in which according to at least one witness, Pinzón objected to the 39 men being " left so far from Spain, being so few, because they could not be provided for and would be lost ", and Columbus threatened to hang Pinzón, the two ships headed together back toward Spain on January 8

According to the historian Robert Lyndsay of Pitscottie, James IV directed in 1493 that a dumb Woman and two infants be transported to the island, in order to ascertain which language the infants would grow up to speak isolated from the rest of the world, thought to be the ' original ' language, or language of the God ( s ).

Following the return of Christopher Columbus from his first voyage in 1493, Pina was one of the commissaries dispatched to Barcelona by John II to negotiate with the Catholic sovereigns respecting the limits of their respective jurisdictions, that would culminate in the Treaty of Tordesillas in 1494.

These people would be established probably in Cuba ( 1492 ) and Puerto Rico ( 1493 ).

Around 1493 ( these sermons have not survived ) he began to prophesy that a New Cyrus was coming over the mountains to begin the renewal of the Church.

Bryan acted as either a feoffee or an owner representing the governing body of the Inn ( there are some records suggesting he may have been a Bencher at this point ) but in 1493 he transferred the ownership by charter to a group including Sir Robert Brudenell and Thomas Wodeward, reverting the ownership of the Inn partially back to the Gray family.

He did have an illegitimate son by Joan Hill, who was alive in 1493, Charles Somerset, 1st Earl of Worcester ( later legitimized ), from whom descend the Earls and Marquesses of Worcester and later the Dukes of Beaufort, who are currently the last male line descendants of the Plantagenets and the Second House of the Counts of Anjou.

In 1492 he helped conclude the Peace of Etaples, and in 1493 he was chief commissioner in the negotiations for the famous commercial agreement with the Netherlands which Bacon seems to have been the first to call the Magnus Intercursus.

From this it can be concluded that he was born in 1492, although if he did not turn 58 till the end of 1550, he could also have been born in 1493.

Whereas Bardach in discussing the beginning of sejm walny points to the national assemblies of the early 15th century, Jędruch prefers, as " a convenient time marker ", the sejm of 1493, the first recorded bicameral session of the Polish parliament ( although as noted by Sedlar, 1493 is simply the first time such a session was clearly recorded in sources, and the first bicameral session might have taken place earlier ).

From 1493 to 1500 Andrea worked in Portugal for the king, and some pieces of sculpture by him still exist in the monastic church of Coimbra.

Aristotle portrayed in the 1493 Nuremberg Chronicle as a 15th-century-A. D. scholar

Bust of Albertus Magnus by Vincenzo Onofri, c. 1493

Zāhir ud-Dīn Mohammad Bābur, who founded the Mughal dynasty of South Asia kept a journal Bāburnāma ( Chagatai /; literally: " Book of Babur " or " Letters of Babur ") which was written between 1493 and 1529.

His most famous publication was the Nuremberg Chronicle, published in 1493 in German and Latin editions.

File: Durer, autoritratto con fiore d ' eringio, dett. jpg | Detail, Portrait of the Artist Holding a Thistle, 1493, Louvre

This study compared several atypical antipsychotics to an older typical antipsychotic, perphenazine, among 1493 persons with schizophrenia.

In 1488 he was appointed Governor of the Netherlands ( until 1493 ) and marched with the imperial forces to free the Roman king Maximilian from his imprisonment at Bruges, and when, in 1489, the King returned to Germany, Albert was left as his representative to prosecute the war against the rebels.

The first European sighting of the Virgin Islands was by Christopher Columbus in 1493 on his second voyage to the Americas.

1493 woodcut of the City of Basel, from the Nuremberg Chronicle.

Paracelsus ( 1493 – 1541 ), for example, rejected the 4-elemental theory, and with only a vague understanding of his chemicals and medicines formed a hybrid of alchemy and science in what was to be called iatrochemistry.

The Mapuche fought against the Sapa Tupac Inca Yupanqui ( c. 1471 – 1493 ) and his army.

Ottoman conquests led to the 1493 Battle of Krbava field and 1526 Battle of Mohács, both ending in decisive Ottoman victories.

With the Papal Bull of 1493, Pope Alexander VI commanded Spain to conquer, colonize and convert the Pagans of the New World to Catholicism.

Christopher Columbus named the island after the day of the week on which he spotted it-a Sunday (' Doménica ' in Italian )-which fell on 3 November 1493 on his second voyage.

On Columbus second voyage in 1493 the colony of " La Española " was founded and administered from the new settlement of La Isabela which was established on the north coast.

The Dance of Death ( 1493 ) by Michael Wolgemut, from the Liber chronicarum by Hartmann Schedel.

The Enchiridion was first published in a Latin translation by Poliziano, Rome, 1493, and in 1496, by Beroaldus, at Bologna.

* 1991 – A runway collision between USAir Flight 1493 and SkyWest Flight 5569 at Los Angeles International Airport results in the death of 34 persons, and the injury of 30 others.

* 1493 – While on board the Niña, Christopher Columbus writes an open letter ( widely distributed upon his return to Portugal ) describing his discoveries and the unexpected items he came across in the New World.

Frederick the Peaceful KG ( September 21, 1415 – August 19, 1493 ) was Duke of Austria as Frederick V from 1424, the successor of Albert II as German King as Frederick IV from 1440, and Holy Roman Emperor as Frederick III from 1452.

In 1493, he was succeeded by his son Maximilian I after ten years of joint rule.

A similar figure was the Swiss magician known as Paracelsus ( 1493 – 1541 ), who published Of the Supreme Mysteries of Nature in which he emphasised the distinction between good and bad magic.