His eldest surviving son, Philip ( 1621 – 1669 ), became 5th Earl of Pembroke, and 2nd Earl of Montgomery ; he was twice married, and was succeeded in turn by three of his sons, of whom Thomas, the 8th Earl ( c. 1656 – 1733 ), was a person of note during the reigns of William III and Anne.

1670 ), eldest son of the 1st Earl, succeeded his grandfather as 2nd Lord Paisley in 1621

In 1621 both titles were surrendered by the 2nd Earl and regranted with a special remainder to his daughters, the eldest of whom, Lady Anne Kerr, succeeded to both titles on his death in 1624.

The title of Baron Montagu of Boughton was first created in 1621, in the Peerage of England, for Sir Edward Montagu, eldest son of Sir Edward Montagu of Broughton Castle and grandson of another Sir Edward Montagu who had been Lord Chief Justice during the reign of Henry VIII.

Heneage Finch, 1st Earl of Nottingham, PC ( 23 December 1621 – 1682 ), Lord Chancellor of England, was descended from the old family of Finch, many of whose members had attained high legal eminence, and was the eldest son of Sir Heneage Finch, recorder of London, by his first wife Frances Bell, daughter of Sir Edmond Bell of Beaupre Hall, Norfolk.

György Rákóczi II György Rákóczi II ( 30 January 1621 – 7 June 1660 ), was a Hungarian nobleman, Prince of Transylvania ( 1648-1660 ), the eldest son of George I and Susanna Lorantffy.

Edward Seymour, 1st Earl of Hertford, KG ( 22 May 1539 – 6 April 1621 ) was the eldest son of Edward Seymour, 1st Duke of Somerset, by his second wife Anne Stanhope.

Lord Lee's eldest son, Sir William Lockhart of Lee ( 1621 – 1675 ), after fighting on the king's side in the English Civil War, attached himself to Oliver Cromwell, whose niece he married, and by whom he was appointed commissioner for the administration of justice in Scotland in 1652, and English ambassador at the French court in 1656, where he greatly distinguished himself by his successful diplomacy.

Philip III was succeeded in 1621 by his son Philip IV of Spain ( reigned 1621 – 1665 ).

Richard II, was the son of Col. Richard Lee I, Esq., " the immigrant " ( 1618 – 1664 ) and Anne Constable ( c. 1621 – 1666 ).

* Stillborn son ( 1621 )

His father was a son of John Doddridge ( 1621 – 1689 ), rector of Shepperton, Middlesex, who resigned his living after the Act of Uniformity of 1662 and became a nonconformist minister, and a great-nephew of the judge and MP Sir John Doddridge ( 1555 – 1628 ).

Richard Johnson's The History of Tom Thumbe of 1621 tells that in the days of King Arthur, old Thomas of the Mountain, a plowman and a member of the King's Council, wants nothing more than a son, even if he is no bigger than his thumb.

Her son Cosimo II died in 1621, leaving his ten-year old son Ferdinando as grand duke.

Robartes was the son of Richard Robartes, who had been created Baronet in July 1621 and Baron Robartes, of Truro, in the Peerage of England in 1626.

During this politically promising time, Massasoit had five children: " Moanam ", or Wamsutta, who was born sometime between 1621 and 1624 ; Pometecomet, Metacomet, or Metacom ; a third son, Sonkanuchoo ; and two daughters, one named Amie and one whose name is unrecorded.

He was the sixteenth and last son of Eidu ( 1562 – 1621 ), who had been a close associate of Nurhaci ( 1559 – 1626 ).

In 1621 an official investigation in Tuscany, Dudley's new country, concluded that Dudley's " friends maintain that his father married Lady Sheffield, but they are unable to account for her marriage during his lifetime, an act so injurious to the alleged legitimacy of her son.

* Grey Brydges, 5th Baron Chandos ( c. 1581 – 1621 ), only son of the 4th Baron

His younger brother, Robert, married Katherine, daughter of the 6th Earl of Cunningham, and their son, William Fergusson had a marriage contract with Sara Grierson, which was signed on 9 May 1621, daughter of Sir William Grierson of Lag, 9th Lord of Lag and their marriage stone, with the three cushions and star of the Griersons, is also to be seen.

Greville obtained from James I a grant of Warwick Castle, and in 1621 he was raised to the Peerage of England as Baron Brooke, of Beauchamps Court in the County of Warwick, with remainder to his second cousin ( once removed ), and adopted son, Robert Greville.

His son Étienne ( born 1621 ) was his pupil.

Richard Lee II, was the son of Col. Richard Lee I, Esq., known as " The Immigrant " ( 1618 – 1664 ) and Anne Constable ( c. 1621 – 1666 ).

In 1621, Philip III died and his son succeeded as Philip IV.

He was the son of Lt. Thomas Putnam Sr. ( 1615 – 1686 ) and Ann Holyoke ( 1621 – 1665 ).

His teachers possibly included Johann Ulrich Steigleder, and he might have met Samuel Scheidt during the latter's visit to Stuttgart in 1627 ; it is possible that Froberger sang in the court chapel, but there is no direct evidence to that ; and court archives indicate that one of the English lutenists employed by the court, Andrew Borell, taught lute to one of Basilius Froberger's sons in 1621 – 22 – it is not known whether this son was Johann Jakob, but if so, it would explain his later interest in French lute music.

In 1613, Virginian raiders captured Port Royale, and in 1621 Acadia was ceded to Scotland's Sir William Alexander who renamed it Nova Scotia.

On the September 29, 1621, a charter for the foundation of a New World Scottish colony was granted by James VI of Scotland to Sir William Alexander.

In 1621, King James granted Sir William Alexander the land in North America between New England and Newfoundland, as Nova Scotia (" New Scotland ").

Nova Scotia was granted in 1621 to Sir William Alexander under charter by James VI.

He married in 1577 Mary Sidney, the famous Countess of Pembroke ( c. 1561 – 1621 ), third daughter of Sir Henry Sidney and his wife Mary Dudley.

Newce sailed to Virginia with Sir Francis Wyatt in October 1621 and was granted of land.

Sir Eubule Thelwall ( principal 1621 – 30 ) spent much of his own money on the construction of a chapel, hall and library for the college.

A gateway designed by Inigo Jones in 1621 at Beaufort House in Chelsea ( home of Sir Hans Sloane ) was bought and removed by Lord Burlington and rebuilt in the gardens at Chiswick in 1738.

In the 1621 version, Sir William Alexander provided a bridge to bring the two stories back into agreement .< Evans, 12-13 > It was known in this cobbled-together fashion until the discovery, in the early twentieth century, of the earlier version.

In 1580, he married Rachel Poulet ( 1564 – 1650 ), daughter of George Poulet ( c. 1533 – 1621 ), Bailiff of Jersey, and granddaughter of Sir Hugh Poulet, Governor of Jersey ( died 1573 ).

; 1621: Sir Henry Finch publishes The World's Great Restauration, or Calling of the Jews, and with them of all Nations and Kingdoms of the Earth to the Faith of Christ

Sir John Coke ( 5 March 1563 – 8 September 1644 ) was an English office holder and politician who sat in the House of Commons at various times between 1621 and 1629.

Sir John Wildman ( c. 1621 – 2 June 1693 ) was an English politician and soldier.

The title of Baron Aungier of Longford was created in the Peerage of Ireland in 1621 for the first Earl's grandfather Sir Francis Aungier, Master of the Rolls in Ireland.

In November 1621, roused by Sir Edward Coke, they framed a petition asking not only for war with Spain but also for Prince Charles to marry a Protestant, and for enforcement of the anti-Catholic laws.

Sir Maurice Abbot ( Morris ) ( 1565 – 1642 ) was an English merchant and politician who sat in the House of Commons between 1621 and 1626.

Sir Edward Herbert ( c. 1591 – 1658 ) was Welsh lawyer and politician who sat in the House of Commons at various times between 1621 and 1641.

Although other editions of the London Pharmacopoeia were issued in 1621, 1632, 1639 and 1677, it was not until the edition of 1721, published under the auspices of Sir Hans Sloane, that any important alterations were made.

Anthony Ashley Cooper, 1st Earl of Shaftesbury PC ( 22 July 1621 – 21 January 1683 ), known as Anthony Ashley Cooper from 1621 to 1631, as Sir Anthony Ashley Cooper, 2nd Baronet from 1631 to 1661, and as The Lord Ashley from 1661 to 1672, was a prominent English politician during the Interregnum and during the reign of King Charles II.