In the early 20th century, before enzymology was well understood, colloids were thought to be the key to the operation of enzymes ; i. e., the addition of small quantities of an enzyme to a quantity of water would, in some fashion yet to be specified, subtly alter the properties of the water so that it would break down the enzyme's specific substrate, such as a solution of ATPase breaking down ATP.

Because fly ash addition allows a lower concrete water content, early strength can also be maintained.

In addition, Commodore made the drive's controller board smaller and having a lower chip count than the early 1541s ( which had a large PCB with dozens of TTL chips running the length of the case ).

The cavalry in the early Roman Republic remained the preserve of the wealthy landed class known as the equites — men who could afford the expense of maintaining a horse in addition to arms and armor heavier than those of the common legions.

The popularity of these terms in the early modern and modern period has resulted in the addition of numerous light-hearted, humorous or " facetious " collective nouns.

In addition, Christina Engelbart spoke about her father's early influences and the ongoing work of the Doug Engelbart Institute.

In addition to ARPANET, and its successor, the Internet, other early worldwide computer networks included Usenet and FidoNet from 1980s, both of which were used to support distributed discussion systems.

The harmony does not include Jesus ' encounter with the adulteress ( John 7: 53 – 8: 11 ), a passage that is generally considered to be a spurious late addition to the Gospel of John, with the Diatessaron itself often used as an early textual witness to support this.

In addition, having been close to him in their youth, she now showed excessive affection towards her uncle – whilst many historians today dismiss this as familial affection ( noting their early friendship, and his similarity to her father and grandfather ), many of Eleanor's adversaries mistook the generous displays of affection between uncle and niece for an incestuous affair.

Among those who were most active in pursuing early structural investigations were, in addition to Kekulé and Couper, Frankland, Wurtz, Alexander Crum Brown, Emil Erlenmeyer, and Aleksandr Mikhailovich Butlerov.

In London in the early 18th century, much gin was distilled legally in residential houses ( there were estimated to be 1, 500 residential stills in 1726 ), and was often flavoured with turpentine-to generate resinous woody notes in addition to the juniper.

In addition to metalcore some early screamo groups, like Circle Takes the Square and Orchid, have been associated with grindcore by some commentators.

In addition, as of early 1988 the government had lost control of several mountainous districts in Kurdistan where, since 1983, dissident Kurds have cooperated militarily with Iran.

In addition to the three early te styles of karate a fourth Okinawan influence is that of Kanbun Uechi ( 1877 – 1948 ).

In addition to these pre-Galfridian Welsh poems and tales, Arthur appears in some other early Latin texts besides the Historia Brittonum and the Annales Cambriae.

Moving clockwise around the outer bailey from Mortimer's Tower, the defences include a west-facing watergate, which would originally have led onto the Great Mere ; the King's gate, a late 17th century agricultural addition ; the Swan Tower, a late 13th century tower with 16th century additions named after the swans that lived on the Great Mere ; the early 13th century Lunn's Tower ; and the 14th century Water Tower, so named because it overlooked the Lower Pool.

In addition to Latin rap in Puerto Rico developing around the same time as early American hip-hop, and rap and reggae simultaneously having a substantial impact on each other, all three genres ( rap, Latin rap, and reggae / dancehall ) relate a certain message to their respective audiences.

In the early 13th century, two German religious orders, the Teutonic Knights and the Livonian Brothers of the Sword, conquered much of the area that is now Estonia and Latvia, in addition to parts of Lithuania.

They are created by the addition of hydrolytic enzymes to early endosomes from the Golgi apparatus.

In addition to Westerns and the science fiction films, three of his early major roles were in noir films, Kansas City Confidential of 1952, Vice Squad of 1953, and The Big Combo of 1955.

In addition, significant numbers of the Tongas live in the north ; Ngonis -- an offshoot of the Zulus who came from South Africa in the early 19th century — live in the lower northern and lower central regions ; and the Yao, who are mostly Muslim, predominate in the Southern Region of the country and live in a wide band from Blantyre and Zomba north to Lake Malawi and east to the border with Mozambique.

In addition the names ikkajo, nikkajo, sankajo used in both Daitō-ryū and the early years of aikido, latter supplanted by terms such as ikkyo, nikkyo, sankyo, were really generic names translating to " first teaching ", " second teaching ", and so on.

In addition to sketching landscape and nature in his early years, he also sketched insects, which frequently appeared in his later work.

No characters from the Kung Fu television series carried over into the comic series, though the character Lu Sung, in an early issue, bears a strong resemblance to Kwai Chang Caine with the addition of a moustache.

In addition to home computers and game consoles, the 6809 was also utilized in a number of arcade games released during the early to mid 1980s.

In 1915, Bertram Sippy introduced the " Sippy regimen " of hourly ingestion of milk and cream, the gradual addition of eggs and cooked cereal, for 10 days, combined with alkaline powders, which provided symptomatic relief for peptic ulcer disease.

In addition, the seed germination period can be 50 days or more, which increases the risk of the seeds rotting before they germinate.

The number of nations playing Test cricket increased gradually over the years, with the addition of West Indies in 1928, New Zealand in 1930, India in 1932, and Pakistan in 1952, but international cricket continued to be played as bilateral Test matches over three, four or five days.

In addition, the lunar tables of the Julian calendar are four days ( sometimes five days ) behind those of the Gregorian calendar.

In addition, without changes to either calendar, the frequency of monthly divergence between the two festivals will increase over time as a result of the differences in the implicit solar years: the implicit mean solar year of the Hebrew calendar is 365. 2468 days while that of the Gregorian calendar is 365. 2425 days.

In addition, articles dictate the form and content of the franchise agreement and define the documents that must be made available 30 days prior to execution.

According to John L. Allen, Jr., " In addition, three decades of bishops ’ appointments by John Paul II and Benedict XVI, both unambiguously committed to “ Humanae Vitae ,” mean that senior leaders in Catholicism these days are far less inclined than they were in 1968 to distance themselves from the ban on birth control, or to soft-pedal it.

In addition, Oyster card users who have failed to touch in at the start of their journey and who are detected mid-journey ( e. g. on a train ) by an Inspector are now liable to a penalty fare of £ 50, reduced to £ 25 if paid within 21 days.

At the Passover seder, it is customary to eat matzah made of flour and water only ; matzah containing eggs, wine, or fruit juice in addition to water is not acceptable for use at the seder, although acceptable during the remaining days of the holiday.

In addition customer service was poor ; fixing a problem might take 10 to 15 days.

In addition to recording heavenly observations and portents, preparing the calendar, and reporting which days were auspicious or not, Zhang was also in charge of an advanced literacy test for all candidates of the Imperial Secretariat and Censorate ( who were expected to know at least 9, 000 Chinese characters and all major writing styles ).

His pioneering efforts encountered specific difficulties, and the treatment of addition was an obvious difficulty in the early days.

In addition to its three provinces, Aragon is subdivided into 33 comarcas or counties ; all with a rich geopolitical and cultural history from its pre-Roman and Roman days ; and from the four centuries of Islamic period as Marca Superior of Al-Andalus or kingdom ( or taifa ) of Saraqustah, and as lands that once belonged to the Frankish Marca Hispanica ; and counties that later formed the Kingdom of Aragon and eventually the empire or Crown of Aragon.

In addition, the bill aimed to curtail ads by non-party organizations by banning the use of corporate or union money to pay for " electioneering communications ," a term defined as broadcast advertising that identifies a federal candidate within 30 days of a primary or nominating convention, or 60 days of a general election.

In addition to the Gospel readings at Matins and Vespers, there is a reading of all four Gospels which takes place during the Little Hours ( Third Hour, Sixth Hour and Ninth Hour ) on these first three days.

In addition to the sciences, English and Journalism are particularly strong, with a long history dating back to Richard Harding Davis's days.

In addition, Monterey Bay Aquarium housed a third great white, a juvenile male, for 162 days between August 27, 2007, and February 5, 2008.

This latter all-star color sequence was a last-minute addition to the film, shot late at night on June 10, 1929, just ten days before the premiere at Grauman's Chinese Theatre.

In addition to the tough instruction ( up to eight months of 12-hour days ), the men had the challenge of dealing with birds roosting overhead in the living quarters with little respect for Navy cleanliness.

In addition, the timing was called into question — by making his admission just two days after the Baseball Hall of Fame announced its class of 2004 inductees, Rose appeared to be linking himself publicly to the Hall.

For he lived after this only two years, two months and twenty days — in addition to the thirty-nine years, five months and twenty-five days he had already lived at that time.