In addition to their targeting component, they also carry a payload-whether this is a traditional chemotherapeutic agent, or a radioisotope, or an immune-stimulating factor.

Palmitoylation is the covalent modification of cysteine ( Cys ) residues via addition of hydrophobic acyl groups, and has the effect of targeting the receptor to cholesterol-and sphingolipid-rich microdomains of the plasma membrane called lipid rafts.

In addition to targeting gang leaders, bombing targets included South African authorities, moderate Muslims, synagogues, gay nightclubs, tourist attractions, and Western-associated restaurants.

Targeting to the outer membrane, intermembrane space, and inner membrane often requires another signal sequence in addition to the matrix targeting sequence.

The Ada 95 revision of the language went beyond the Steelman requirements, targeting general-purpose systems in addition to embedded ones, and adding features supporting object-oriented programming.

In addition, UNCTAD conducts certain technical cooperation in collaboration with the World Trade Organization through the joint International Trade Centre ( ITC ), a technical cooperation agency targeting operational and enterprise-oriented aspects of trade development.

In addition, MEPs are used as a reference to adjust the intensity of stimulation that need to delivered by TMS when targeting cortical regions whose response might not be as easily measurable, e. g., in the context of TMS-based therapy.

In addition, many bands moved further away from the era towards mainstream hard rock, with Def Leppard in particular targeting the American market with a more refined sound despite having major success.

In addition to bomb damage assessment, targeting and aerial photography for Far East Air Forces, the 91st conducted ELINT ( Electronic Signals Intelligence ) and “ ferret ” missions to probe Soviet air defenses in theater and give an indication of just where the holes were in Soviet radar coverage.

The WWE says that the addition of WWE SmackDown to Syfy programming will assist with their targeting of young male and female audiences.

In addition to targeting organisms in solid tissue, primarily with drugs like metronidazole and chloroquine, treatment of liver abscess must include agents that act in the lumen of the intestine ( as in the preceding paragraph ) to avoid re-invasion.

In addition, riding on the success of ET Press, WHY Publishing aims at targeting young readers.

In addition, it is more suitable to the targeting of specific groups within the population of the EU, to find out their opinions on the topic in question.

In addition to targeting Toronto, the station also reaches its strong signal into Barrie and Kitchener.

IGN called this new system " a beneficial addition ", and GameSpot stated it " makes targeting a cinch ".

In addition, two community stations, Radio North Wales ( targeting the whole region ) and Llangefni-based Mon FM ( targeting Anglesey ), broadcast online.

The IRA claimed they were targeting a Loyalist meeting above the fish shop when the bomb exploded prematurely as it was being planted ; nine people were killed in addition to one of the bombers, Thomas Begley.

In addition, targeting certain neighborhoods with a history of voting for one political party while not targeting areas dominated by the opposing party may lead to a racial component in the disqualifications which raises a serious legal issue under the Voting Rights Act.

MTV airs the show several times during daytime hours in addition to its regular timeslots around 10: 00 PM ( ET ), and the PTC claimed that the adolescents whom MTV is targeting are being exposed to " excessive sexual and profane content through inaccurately rated programs.

In addition to powering the community web sites, DataSphere provides enhanced functionality, including market-leading site search, coupons, a business directory and ad targeting.

* In 2008 in the context of an ideological crisis in Israel caused by record-low and shrinking aliya figures, Israel's Immigration Absorption Ministry embarked on a new mission targeting Israeli emigrants, the ' Israeli ' Diaspora, in addition to the Jewish diaspora under the title of " Returning Home on Israel's 60th.

In addition to contextual targeting, online advertising can be targeted based on a user's online behavior.

In addition, the seed germination period can be 50 days or more, which increases the risk of the seeds rotting before they germinate.

In addition, manufacturers are now obliged to provide conformity risk assessments and test reports – or explain why they are lacking.

In addition, training with a bokken does not carry the same mortal risk associated with that of a live sword, both for the user and other practitioners near by.

In addition to assessing the market-related risks that may arise from an investment, investors commonly employ operational due diligence to assess the risk that error or fraud at a hedge fund might result in loss to the investor.

In addition, investors, particularly institutional investors, are encouraging further developments in hedge fund risk management, both through internal practices and external regulatory requirements.

In addition, people on daily aspirin therapy ( e. g., for reducing cardiovascular risk ) must be careful if they also use other NSAIDs, as the latter may block the cardioprotective effects of aspirin.

In addition to the promise of earlier completion of the Panama canal, opponents of the Nicaraguan canal cited the risk of volcanic activity at the Momotombo volcano.

In addition, individuals with the HLA-DR1 or HLA-DR4 serotypes have an increased risk for developing the disorder.

In addition to genetic fingerprinting, RFLP was an important tool in genome mapping, localization of genes for genetic disorders, determination of risk for disease, and paternity testing.

In addition, psychologists were reluctant to risk being associated with the German Nazi claims of a " master race ".

The EPA emphasizes that synergy does not always make a mixture dangerous, nor does antagonism always make the mixture safe ; each depends on the predicted risk under dose addition.

In addition, in 2007 the U. S. Food and Drug Administration ( FDA ) approved an endotracheal breathing tube with a fine coat of silver for use in mechanical ventilation, after studies found it reduced the risk of ventilator-associated pneumonia.

In addition, a retrospective case-control study published by researchers from the Mayo Clinic in 2006 has found an increased risk of developing diabetes mellitus and hypertension in people who had undergone ESWL, compared with age and gender-matched people who had undergone nonsurgical treatment.

In addition to problems in science and mathematics, the method has been applied to: finance, social science, environmental risk assessment, linguistics, radiation therapy, sports, and many other fields.

In addition, participants do not necessarily purchase annuities with their savings upon retirement, and bear the risk of outliving their assets.

This is in addition to those who have dysplastic nevi being at higher risk of this cancer.

In addition, minority ethnic groups, including first or second-generation immigrants, have been found to be at greater risk for developing mental disorders, which has been attributed to various kinds of life insecurities and disadvantages, including racism.

In addition to the risk of cyclist / pedestrian collisions, cyclists face increase risks from collisions with motor vehicles at street crossings and driveways.

The risk of his patents being infringed was something which particularly exercised Watt, and so Murdoch was, in addition to his other activities, called upon to make reports and swear out affidavits for legal actions against Boulton & Watt's competitors.

The addition of the Windows Key to keyboards may have been part of the reason why most current games have evolved their control schemes, and most first person shooters generally use the mouse in conjunction with a " Half-Life " style of control ( W, A, S, D, Space, Shift, Ctrl ) named apparently because it may have been the first widespread game to popularize such an interface, and because usage of the Alt button would nowadays heighten the risk of accidentally pressing the Windows Key.

In addition, most of the courses also feature a mini game that will put seven melons at stake, further increasing the risk of failure, as the player must successfully win every piece.

These sanctions resulted in South African Airways being refused rights to fly over most African countries, and in addition to this the risk of flying over some African countries was emphasised by the shooting down of two passenger aircraft over Rhodesia, forcing them to fly around the " bulge " of Africa.

In addition to these complications, tracheal intubation via the nasal route carries a risk of dislodgement of adenoids and potentially severe nasal bleeding.

They can also be used in addition to hand washing, to minimize risks when caring for " at risk " groups.