In fact, the enzyme-linked immunosorbent assay ( ELISA ), which uses antibodies, is currently one of the most sensitive tests modern medicine uses to detect various biomolecules.

* Margaret Thatcher who had been the United Kingdom's Prime Minister since 1979 resigned as Prime Minister on 22 November 1990 after being challenged for the leadership of the Conservative Party by Michael Heseltine because of widespread opposition to the introduction of the controversial Community Charge and the fact that her key allies such as Nigel Lawson and Geoffrey Howe resigned over the deeply sensitive issues of the Maastricht Treaty and Margaret Thatcher's resistance to Britain joining the European Exchange Rate Mechanism.

The Second World War had a profound effect on Brzezinski, stating in an interview ; " The extraordinary violence that was perpetrated against Poland did affect my perception of the world, and made me much more sensitive to the fact that a great deal of world politics is a fundamental struggle.

Other flavors include reflection EELS ( including reflection high-energy electron energy-loss spectroscopy ( RHEELS ), typically at 10 to 30 keV ) and aloof EELS ( sometimes called near-field EELS, in which the electron beam does not in fact strike the sample but instead interacts with it via the long-ranged Coulomb interaction ; aloof EELS is particularly sensitive to surface properties but is limited to very small energy losses such as those associated with surface plasmons or direct interband transitions ).

The surviving TPVs were, in fact, hidden from the top management by some workers who were sensitive to their historical value.

The fact that, for all this, he was a sensitive and lovable character rather than an out-and-out hell-raiser made him such a unique human being ".

The group's deliberations were sensitive and highly secret, dealing as they did with the highly classified fact that there was a covert side to the Marshall Plan, where the CIA used certain funds to aid anti-communist groups in France and Italy.

He was brought, along with his printing press to Rogersville by the new governor of the Southwest Territory, William Blount, who was sensitive to the fact that government could not exist without printing.

This structure is no longer open to the public due to safety concerns, and the fact that Eliza Spring has become a sensitive habitat area for the endangered Barton Springs Salamander.

However, it is never made explicitly clear how many screens are monitored at once, or what the precise criteria ( if any ) for monitoring a given screen are ( although we do see that during an exercise program that Winston takes part in every morning, the instructor can see him, meaning telescreens are possibly a variant of videophones ); Telescreens do not have night vision technology, thus, they cannot surveil in the dark ; this is compensated by the fact that telescreens are incredibly sensitive, and can pick up a heartbeat.

Such snares are termed “ flypaper traps ,” however the trapping mechanism of sundews is often erroneously described as “ passive .” In fact, sundew traps are quite active and sensitive, and the disturbance of one or a few trichomes quickly triggers an action potential that stimulates the rapid movement of other trichomes toward the prey.

Dynamic range was also limited by the fact that if the signal level coming from the master tape was too high, the highly sensitive cutting head might jump off the surface of the disc during the cutting process.

While slightly frightening to those who don't know him, The Hobgoblin is in fact a rather lonely and sensitive creature, who can grant the wishes of others but not his own — unless somebody specifically asks him for something which he wants, and then gives him what he himself created.

" Justice Blackmun suggested that " nly the most willful blindness could obscure the fact that sexual intimacy is ' a sensitive, key relationship of human existence, central to family life, community welfare, and the development of human personality '" ( ironically quoting from the opinion by Chief Justice Burger in Paris Adult Theatre I v. Slaton, which held that obscene films are not constitutionally protected ).

" After a visit to the doctor Gloria explains to Archie that he needs to be sensitive to the fact that Edith is going through menopause.

Some believe that the fact that Washoe not only communicated, but also formed close and personal relationships with humans indicates that she is emotionally sensitive and is deserving of moral status.

Newton carried on the discussion with the objectors with great courtesy and patience, but the amount of pain which these perpetual discussions gave to his sensitive mind may be estimated from the fact of his writing on 18 November 1676 to Oldenburg: " I promised to send you an answer to Mr Lucas this next Tuesday, but I find I shall scarce finish what I have designed, so as to get a copy taken of it by that time, and therefore I beg your patience a week longer.

It is based on the fact that the normal human eye sees color because its inner surface is covered with millions of intermingled cone cells of three types: one more sensitive than the others to the end of the spectrum we call " red ", one more sensitive to the middle or " green " region, and one which is most strongly stimulated by " blue ".

To account for the fact that humans may be more or less sensitive than the test animal, a 10-fold uncertainty factor is usually applied to the NOEL.

An additional 10-fold uncertainty factor, the " intraspecies uncertainty factor " or Uf < sub > intra </ sub >, is usually applied to account for the fact that some humans may be substantially more sensitive to the effects of substances than others.

This scheme, known as " companding " or " compressing-expanding ", exploits the fact that the fidelity of voice signals is more sensitive to high amplitudes than to low amplitudes.

His evidence for this was the fact that Asher ben Jehiel, a German who became chief rabbi of Toledo, never refers to any difference of pronunciation, though he is normally very sensitive to differences between the two communities.

In retrospect, the letter is sometimes pointed at as a significant warning of the crisis and deadlock that came to signify the European Union the following years, with its inability to move forward the issues of defense cooperation, constitution, " transparency " and democratic legitimacy, or integration of the new member countries ; and it has been questioned whether the governments in question in fact acted supportive of Anglo-Saxon interests critical or fearful of a strengthened EU, which these governments with their fresh experience of the Soviet Union's detrimential dominance on national independence might have been sensitive for.

The very nature of a choice so grounded in distinction and fact leads to the valid convictions which become force of will in the manifest leader.

Perhaps the mere fact that by plucking on the nerves nature can awaken in the most ordinary of us, temporarily anyway, the sleeping poet, and in poets can discover their immortality, is the most remarkable of all the remarkable phenomena to which we can attest??

Among Christian groups, the Mennonites have commonly been aware more than others of the fact that the nature of divine charity raises decisively the question of the Christian use of all forms of pressure.

::" When it is asked, What is the nature of all our reasonings concerning matter of fact?

If he himself philosopher did not exist, he would not be there to ask questions about the nature of reality ... on the other hand, this fundamental fact, which we call existence, soon proves a rather barren topic for philosophic speculation ...

In fact, due to the repetitious nature of some of phrases or intertextuality with Jeremiah, an argument has been put forth that the “ historical Jeremiah ” is hard to validate and should be abandoned.

The conservative nature of these changes underlines the fact that Protestantism was by no means universally popular – a fact that the queen herself recognized: her revived Act of Supremacy, giving her the ambiguous title of Supreme Governor passed without difficulty, but the Act of Uniformity 1559 giving statutory force to the Prayer Book, passed through the House of Lords by only three votes.

In fact, a dictum of classical physics states that in nature everything is continuous.

The natural abundance of hydrogen ( H < sub > 2 </ sub >) in the Earth's atmosphere is only on the order of parts per million, but H < sub > 2 </ sub > is, in fact, the most abundant diatomic molecule in nature.

The nature of interaction between early humans and these sister species has been a long standing source of controversy, the question being whether humans replaced these earlier species or whether they were in fact similar enough to interbreed, in which case these earlier populations may have contributed genetic material to modern humans.

* The 1977 book Gnomes by Wil Huygen and Rien Poortvliet was written as a nature study of gnomes and their way of life presented as fact.

Critics have objected to GMOs on several grounds, including tampering with nature, ecological concerns, economic concerns raised by the fact these organisms are often subject to intellectual property law, whether food produced from GMOs should be banned or labelled, whether such food is safe, and whether GM crops are useful to address the world's food needs.

The fact that all currently known ( 2009 ) matter particles fit nicely into three copies of the smallest group representations of SU ( 5 ) and immediately carry the correct observed charges, is one of the first and most important reasons why people believe that a Grand Unified Theory might actually be realized in nature.

It could never be right for her to declare lawful what is in fact unlawful, since that, by its very nature, is always opposed to the true good of man.

Such fiction is said to emphasize the fact that human consciousness, being finite in nature, can never make complete sense of, or successfully order, a universe that is infinite in its aspects and possibilities.

It appears to be a fact of nature that identical particles do not occupy states of a mixed symmetry, such as

It may be that irreducible complexity does not actually exist in nature, and that the examples given by Behe and others are not in fact irreducibly complex, but can be explained in terms of simpler precursors.

Contrary to Professor Behe ’ s assertions with respect to these few biochemical systems among the myriad existing in nature, however, Dr. Miller presented evidence, based upon peer-reviewed studies, that they are not in fact irreducibly complex.

The chemist Ernest Lester Smith wrote a book Intelligence Came First ( 1975 ) in which he claimed that consciousness is a fact of nature and that the cosmos is grounded in and pervaded by mind and intelligence.

On the contrary, Rousseau holds that " uncorrupted morals " prevail in the " state of nature " and he especially praised the admirable moderation of the Caribbeans in expressing the sexual urge despite the fact that they live in a hot climate, which " always seems to inflame the passions ".

Contrary to what his many detractors have claimed, Rousseau never suggests that humans in the state of nature act morally ; in fact, terms such as " justice " or " wickedness " are inapplicable to prepolitical society as Rousseau understands it.

Marx thus departs from Hegel by insisting that " the fact that man is a corporeal, actual, sentient, objective being with natural capacities means that he has actual, sensuous objects for his nature as objects of his life-expression, or that he can only express his life in actual sensuous objects.

In fact the widespread worship of Guanyin as a " Goddess of Mercy and Compassion " is seen as the boundless salvific nature of bodhisattva Avalokitesvara at work ( in Buddhism, this is referred to as Guanyin's " skillful means ", or upaya ).

Its fame rests, in particular, on the elusive smile on the woman's face, its mysterious quality brought about perhaps by the fact that the artist has subtly shadowed the corners of the mouth and eyes so that the exact nature of the smile cannot be determined.