In general, globular proteins and albumin are in lower concentration in ventricular CSF compared to lumbar or cisternal fluid.

Hemoglobin has a quaternary structure characteristic of many multi-subunit globular proteins.

Proteins can be informally divided into three main classes, which correlate with typical tertiary structures: globular proteins, fibrous proteins, and membrane proteins.

Almost all globular proteins are soluble and many are enzymes.

In particular, globular proteins are comparatively easy to crystallize in preparation for X-ray crystallography.

When proteins bind specifically to other copies of the same molecule, they can oligomerize to form fibrils ; this process occurs often in structural proteins that consist of globular monomers that self-associate to form rigid fibers.

Most structural proteins are fibrous proteins ; for example, actin and tubulin are globular and soluble as monomers, but polymerize to form long, stiff fibers that make up the cytoskeleton, which allows the cell to maintain its shape and size.

The mechanism for unfolding of globular proteins is necessarily general, but somewhat dependent on the amino acid sequence.

Some such proteins are highly specific in their function, such as protein disulfide isomerase ; others are very general and can be of assistance to most globular proteins-the prokaryotic GroEL / GroES system and the homologous eukaryotic Heat shock proteins Hsp60 / Hsp10 system fall into this category.

More is known about the tertiary structural features of soluble globular proteins than about membrane proteins because the latter class is extremely difficult to study using these methods.

The first predicted structure of globular proteins was the cyclol model of Dorothy Wrinch, but this was quickly discounted as being inconsistent with experimental data.

Dr. Max Ferdinand Perutz, OM, CH, CBE, FRS ( 19 May 1914, Vienna, Austria – 6 February 2002, Cambridge, United Kingdom ) was an Austrian-born British molecular biologist, who shared the 1962 Nobel Prize for Chemistry with John Kendrew, for their studies of the structures of hemoglobin and globular proteins.

In addition to the Nobel Prize for Chemistry in 1962, which he shared with John Kendrew for their studies of the structures of hemoglobin and globular proteins, Max Perutz received a number of other important honors: he was appointed Commander of the Order of the British Empire in 1963, received the Österreichisches Ehrenzeichen für Wissenschaft und Kunst in 1967, the Royal Medal in 1971, the Copley Medal in 1979, the Companions of Honour in 1975, and the Order of Merit in 1989.

The α-helix and β-sheet motifs, and disulfide bridges, are crucial to the conformations of globular, functional proteins like enzymes, many of which operate semi-independently, but they take on a completely dominant role in the architecture and aggregation of keratins.

A well studied example is the bacterial GroEL system, which assists in the folding of globular proteins.

Although most globular proteins are able to assume their native state unassisted, chaperone-assisted folding is often necessary in the crowded intracellular environment to prevent aggregation ; chaperones are also used to prevent misfolding and aggregation that may occur as a consequence of exposure to heat or other changes in the cellular environment.

Myoglobin and hemoglobin are globular proteins that serve to bind and deliver oxygen.

The term globular protein is quite old ( dating probably from the 19th century ) and is now somewhat archaic given the hundreds of thousands of proteins and more elegant and descriptive structural motif vocabulary.

The tertiary structure of ricin was shown to be a globular, glycosylated heterodimer of approximately 60-65 kDA.

As with many other rich galaxy clusters, Virgo's intracluster medium is filled with a hot, rarefied plasma at temperatures of 30 million Kelvin that emits X-Rays, and within it can be found a large number of intergalactic stars ( up to 10 % of the stars in the cluster ), including some planetary nebulae, that it's theorized were expelled of their home galaxies on interactions with other galaxies, as well as some globular clusters, possibly stripped of dwarf galaxies, and even at least one star formation region

A promising exception to this limitation is the discovery by Marcelo Moret and Gilney Zebende that the globular compaction of protein chains by hydrophobic interactions is describable in non-Euclidean terms, with fractal critical exponents inferred from the evolution of solvent-accessible surface areas in chain segments of increasing length.

Cacti whose stems are even smaller may be described as globular ( or globose ).

Globular clusters are fairly common ; there are about 150 to 158 currently known globular clusters in the Milky Way, with perhaps 10 to 20 more still undiscovered.

Although it appears that globular clusters contain some of the first stars to be produced in the galaxy, their origins and their role in galactic evolution are still unclear.

It does appear clear that globular clusters are significantly different from dwarf elliptical galaxies and were formed as part of the star formation of the parent galaxy rather than as a separate galaxy.

Towards the north of the constellation are globular clusters NGC 5824 and NGC 5986, and close by the dark nebula B 228.

To the south are two open clusters, NGC 5822 and NGC 5749, as well as globular cluster NGC 5927 on the eastern border with Norma.

Before their nature was understood, galaxies (" spiral nebulae ") and globular clusters were also classified as nebulae, but no longer are.

Modifications ( such as acetylation or phosphorylation ) that lower the charge of the globular histone core are predicted to " loosen " core-DNA association ; the strength of the effect depends on location of the modification within the core.

These blue stragglers are also observed in globular clusters, and in the very dense cores of globulars they are believed to arise when stars collide, forming a much hotter, more massive star.

Proteins ( or ) are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function.

Two types of star clusters can be distinguished: globular clusters are tight groups of hundreds of thousands of very old stars which are gravitationally bound, while open clusters, more loosely clustered groups of stars, generally contain fewer than a few hundred members, and are often very young.

In our galaxy, globular clusters are distributed roughly spherically in the galactic halo, around the galactic centre, orbiting the centre in highly elliptical orbits.

A few of the brightest globular clusters are visible to the naked eye, with the brightest, Omega Centauri, having been known since antiquity and catalogued as a star before the telescopic age.

Currently, there are not any intermediate clusters ( also known as extended globular clusters ) discovered in the Milky Way.

What distinguishes them from the globular clusters is that they are much larger – several hundred light-years across – and hundreds of times less dense.

In addition to these general stellar attributes, globular clusters are found more frequently in lenticular galaxies than in spiral galaxies of similar mass and luminosity.

Its apparent magnitude is 10. 6, and it is unique because it is younger than most other globular clusters in the same region as determined by its metallicity.

Its status as a globular cluster was determined by James Dunlop in 1827.

Some stars in globular clusters appear to be as old as the universe itself ( by entirely different measurement and analysis methods ).

A different method by Harlow Shapley based on the cataloguing of globular clusters led to a radically different picture: a flat disk with diameter approximately 70 kiloparsecs and the Sun far from the center.

However, recent conjectures by astronomers suggest that globular clusters and dwarf spheroidals may not be clearly separate and distinct types of objects.

The globular and wall maps were accompanied by a book Cosmographiae Introductio, an introduction to cosmography.

In 1917, the astronomer Harlow Shapley was able to estimate the Sun's distance from the galactic centre based on the distribution of globular clusters ; previously the Sun's location within the Milky Way was by no means well established.

Our galaxy has about 150 globular clusters, some of which may have been captured from small galaxies disrupted by the Milky Way, as seems to be the case for the globular cluster M79.

They are characterized by their large size compared to globular clusters and a ringlike distribution around the centers of their host galaxies.

Being much less densely populated than globular clusters, they are much less tightly gravitationally bound, and over time, are disrupted by the gravity of giant molecular clouds and other clusters.

* 1930 — Robert Trumpler discovers absorption by interstellar dust by comparing the angular sizes and brightnesses of globular clusters

* Lagash — A planet in the story Nightfall by Isaac Asimov, in a globular cluster, and in a system with six suns.

The globular nature of these proteins can be determined without the means of modern techniques, but only by using ultracentrifuges or dynamic light scattering techniques.

* Regulatory roles are also performed by globular proteins rather than fibrous proteins.

The town's oldest surviving monument is the Assumption Cathedral ( 1689 ), an imposing structure surmounted by five globular domes.

Altocumulus ( Alto, " high ", cumulus, " heaped ") is a cloud belonging to a class characterized by globular masses or rolls in layers or patches, the individual elements being larger and darker than those of cirrocumulus and smaller than those of stratocumulus.

The protein has two approximately symmetrical globular domains ( the N-and C-domain ), separated by a flexible linker region.

Originally thought to be a star, NGC 2419 was discovered to be a globular cluster by Carl Lampland.

Some, such as the cockles, are nearly globular and can jump by bending and straightening the foot.

Blue stragglers were first discovered by Allan Sandage in 1953 while performing photometry of the stars in the globular cluster M3.