Like other nuclear receptors, the androgen receptor protein consists of several functional domains: the transactivation domain ( also called the transcription-regulation domain or the amino / NH2-terminal domain ), the DNA-binding domain, the hinge region, and the steroid-binding domain ( also called the carboxyl-terminal ligand-binding domain ).

Like other nuclear receptors, the androgen receptor is modular in structure and is composed of the following functional domains labeled A through F:

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