Most mutations in CMT affect the myelin sheath, but some affect the axon.

Most, but not all, mutations in regulatory genes result in non-viable zygotes.

Most oncogenes require an additional step, such as mutations in another gene, or environmental factors, such as viral infection, to cause cancer.

Most of these mutations destroy the ability of the protein to bind to its target DNA sequences, and thus prevents transcriptional activation of these genes.

Most of the short sequence repeats within protein-coding portions of the genome have a repeating unit of three nucleotides, since that length will not cause frame-shift mutations ( Sutherland 1995 ).

Most Tay – Sachs mutations probably do not directly affect protein functional elements ( e. g., the active site ).

Most ( 60 %) are homozygous for ATP7B mutations ( two abnormal copies ), and 30 % have only one abnormal copy.

Most patients who are homozygous for HFE mutations will not manifest clinically relevant haemochromatosis ( see Genetics below ).

' Most people had thought that they were " tank-bred mutations ", " ugly creatures who excreted slimy, foul-smelling residue, and whose multiple mouths ground incessantly on garbage ", even though they enjoy devouring the flesh of these beasts ( marinated slig medallions in rich Caladan wine sauces are considered a prime delicacy ).

Most of the mutations either are inferior to the parent virus ( often lacking the ability to reproduce at all ) or convey no advantage, but some of them have a natural selection superiority to their parent and can enable them to slip past defenses such as the human immune system and antiretroviral drugs.

Most loss of function mutations are selected against.

Most of those mutations are missense mutations and inherited mostly in a dominant manner.

Most WFS1 mutations replace one of the protein building blocks ( amino acids ) used to make wolframin with an incorrect amino acid.

Most cases do not have mutations in any of these genes.

Most proteins can withstand one or two point mutations before their functioning changes.

Most retrotransposons are very old and through accumulated mutations, are no longer able to retrotranspose.

Most mutations are disasters, but perhaps some inspired few are not.

Most of the known causes of congenital heart disease are sporadic genetic changes, either focal mutations or deletion or addition of segments of DNA.

Most cases appear to be due to three mutations.

Most of the stock of ' Bramley's Seedling ' commercially available is slightly different in its growth habit and other characteristics from the original tree, probably because of a chance mutation ( or mutations ) that occurred unnoticed over the years.

Most commonly, patients have mutations in the PEX1, PEX2, PEX3, PEX5, PEX6, PEX10, PEX12, PEX13, PEX14, PEX16, PEX19, and PEX26 genes.

Most of these mutations either substitute one amino acid ( a building block of proteins ) for another amino acid in the CFTR protein or delete a small amount of DNA in the CFTR gene.

Most mutations are detrimental.

Most genetic disorders involve more than one gene.

Most felids are unable to taste sweetness due to a mutated gene in their taste buds.

Most of what researchers have deduced about channel operation so far they have established through electrophysiology, biochemistry, gene sequence comparison and mutagenesis.

Most, however, may be regarded as belonging to large or small groups of related species, which are often in geographical contact with each other and between which gene exchange still occurs.

Most genetic systems involve complex epistatic interactions among multiple gene loci.

Most thinking in genetics has focused on vertical transfer, but there is a growing awareness that horizontal gene transfer is a significant phenomenon.

Most black spot resistant cultivars developed around the world carry this gene, but there are some selections that carry the Vr ( from M. pumila ) or Vm ( from M. micromalus ) gene.

Most thinking in genetics has focused upon vertical transfer, but there is a growing awareness that horizontal gene transfer is a highly significant phenomenon and amongst single-celled organisms perhaps the dominant form of genetic transfer.

Most of these are single gene defects, usually heritable.

However, Most percentages of people who were born to at least one parent with a recessive trait or gene will most likely have the recessive trait or gene unless it goes to the sibling.

Most mammals, including naked mole rats, have the gene p27 which does a similar task, but prevents cellular reproduction at a much later point than p16 does.

Most ( 50-80 %) GISTs arise because of a mutation in a gene called c-kit.

Most evidence to date suggests that this is probably due to activation of the dsRNA sensor PKR, although retinoic acid-inducible gene I ( RIG-I ) may also be involved.

Most of the research concentrated upon the trancriptome, proteome and metabolome profiling of various developmental stages have shown that all possible mode of gene actions contribute to heterosis although to different extent in different hybrid.

Most population genetics considers changes in the frequencies of alleles at a small number of gene loci.

Most often, the parents of a child with an autosomal recessive disorder are not affected but are carriers of one copy of the altered gene.

Most genes are not imprinted and both the maternal and paternal copies of the gene are actively expressed.

Most often, the parents of a child with an autosomal recessive disorder are not affected but are carriers of one copy of the altered gene.

Most solid colored cats result from a recessive gene that suppresses the tabby pattern.

Most critically lacking as corroboration was the examination of other phenotypic markers, besides the capsular polysaccharide, to determine the extent that the findings on the gene for one pneumococcal antigen would apply to other metabolic markers of S. pneumoniae.

Most Morpholinos are used as research tools for reverse genetics by knocking down gene function.