Drugs including the monoamine oxidase inhibitors ( MAOIs ), tricyclic antidepressants ( TCAs ), tetracyclic antidepressants ( TeCAs ), selective serotonin reuptake inhibitors ( SSRIs ), and serotonin-norepinephrine reuptake inhibitors ( SNRIs ) are most commonly associated with the term.

Selective serotonin reuptake inhibitors ( SSRIs ) are the class of antidepressants commonly used as the first-line treatment for depression because they have a favorable side effect profile and low toxicity.

Selective serotonin reuptake inhibitors or serotonin-specific reuptake inhibitor ( SSRIs ) are a class of compounds typically used as antidepressants in the treatment of depression, anxiety disorders, and some personality disorders.

SSRIs are primarily classified as antidepressants and typically higher dosages are required to be effective against anxiety disorders than to be effective against depression but nevertheless most SSRIs have anxiolytic properties, but are anxiogenic when first initiating treatment, and in some individuals continue to be anxiety-provoking.

Selective serotonin reuptake inhibitors are likely to be the best choice of pharmacotherapy for many patients with panic disorder, but benzodiazepines are also often used, and some studies suggest that these medications are still used with greater frequency than the SSRIs.

* Drugs ( anti-depressants ( SSRIs ) and nicotine are most common )

In recent times, the TCAs have been largely replaced in clinical use in most parts of the world by newer antidepressants such as the selective serotonin reuptake inhibitors ( SSRIs ) and serotonin-norepinephrine reuptake inhibitors ( SNRIs ), which typically have more favorable side-effects profiles, though they are still sometimes prescribed for certain indications.

Although they are still considered to be highly effective, they have been increasingly replaced by antidepressants with an improved safety and side effect profile, such as the SSRIs and other newer antidepressants such as the novel reversible MAOI moclobemide.

SSRIs are less likely to trigger manic symptoms.

Most SSRIs are available generically and are relatively inexpensive.

The SSRIs are relatively safe in overdose and better tolerated than the TCAs and MAOIs for most patients.

Such drugs are called selective serotonin reuptake inhibitors ( SSRIs ), and they actively prevent these neurotransmitters from dropping to the levels at which depression is experienced.

Bi-functional SSRIs are currently being researched, which will occupy the autoreceptors instead of ' throttling ' serotonin.

MAOIs are typically only used when tricyclic antidepressants or SSRIs exacerbate or fail to prevent depression.

In 2003, the UK Medicines and Healthcare products Regulatory Agency issued a guidance that, apart from fluoxetine ( Prozac ), SSRIs are not suitable for the treatment of depression in patients under 18.

Recent scientific studies have shown that cognitive behavioral therapy ( CBT ) and selective serotonin reuptake inhibitors ( SSRIs ; e. g., fluoxetine and paroxetine ) are effective treatment options for hypochondriasis as demonstrated in clinical trials.

* SSRIs ( selective serotonin reuptake inhibitors ) comprise a class of medicines commonly used for depression, and are also said to be effective in controlling pruritus in a small number of refractory cases.

Work by two researchers has called into question the link between serotonin deficiency and symptoms of depression, noting the efficacy of SSRIs as treatment does not in itself prove the link.

Reduced libido is also often iatrogenic and can be caused by many medications, such as hormonal contraception, SSRIs and other antidepressants, antipsychotics, opioids and beta blockers.

PMDD has been found by PET scans to be associated with dysregulation of serotonin pathways in the brain and to respond quickly and powerfully to SSRIs.

SSRIs will often take 3 – 5 weeks to have a noticeable effect: the brain struggles to process the flood of serotonin, and reacts by downregulating the sensitivity of the autoreceptors, which can take up to 5 weeks.

Naturally the other SSRIs which are metabolized by CYP2D6 will have more CYP2D6-based interactions with TCAs, antiarrhythmics, B-blockers, phenytoin, opioids and neuroleptics.

SSRIs selectively inhibit the reuptake of serotonin by acting upon SERT.

Though reporting of anorgasmia as a side effect of SSRIs is not precise, studies have found that 17 – 41 % of users of such medications are affected by some form of sexual dysfunction.

This theory is further supported by the proven effectiveness of selective serotonin reuptake inhibitors ( SSRIs ), which increase serotonin level in the synapse, in treating Premature Ejaculation.

Some studies using SSRIs have observed that opioid antagonists appear to reduce the urge to steal and mute the " rush " typically experienced immediately after stealing by some subjects suffering from kleptomania.

In Australia, although PMDD is recognized by the Therapeutic Goods Administration, SSRIs are not reimbursed for it under the Pharmaceutical Benefits Scheme.

** SSRIs — class of antidepressants that increase active serotonin levels by inhibiting reuptake, also shown to promote Neurogenesis in the hippocampus

Yohimbine has also been used for the treatment of sexual side effects caused by some antidepressants ( SSRIs ), female hyposexual disorder, as a blood pressure boosting agent in autonomic failure, xerostomia, and as a probe for noradrenergic activity.

In contrast to Breggin's Talking Back to Prozac, which was largely ignored by the press on its release, Prozac Backlash, a critique of SSRIs by Harvard psychiatrist Joseph Glenmullen was widely praised by high-profile media sources.

Targeted to treat addictions by interrupting neurotransmitters, these synthetic chemical hormones attempt to adjust behavior through the effect of reducing libido, SSRIs have been used in research studies and off-label to treat symptoms of overly frequent sexual urges, but their effects are not always robust.

Similar to individual variations of inherited medical conditions, lethal allergies, regional nutritional deficiencies, toxic environmental issues of nuclear / oil / chemical disasters and genetic differences, the synthetic pharmaceutical SSRIs have erratic track records with dangerously fluctuating side effects triggered by random DNA coding data.

They argue that dermatillomania differs from OCD in the following fundamental ways: ( 1 ) there is a much greater share of females with dermatillomania ; ( 2 ) dermatillomania may be inherently pleasurable whereas OCD is not ; ( 3 ) the treatments that are generally effective for patients with OCD, ( i. e., SSRIs and exposure therapy ) are not as successful in patients with dermatillomania ; and ( 4 ) unlike OCD, picking the skin is rarely driven by obsessive thoughts.

Dizziness could be provoked by the use of antihistamine drugs, like Xyzal ( Levocetirizine ) or by some antibiotics or SSRIs.

It can also reduce the side effects caused by selective serotonin reuptake inhibitors, including Parkinsonism syndrome as well as sexual dysfunction and erectile dysfunction caused by either SSRIs or antipsychotics.

The choice of treatment between benzodiazepines, SSRIs, serotonin – norepinephrine reuptake inhibitors, tricyclic antidepressants, and psychotherapy should be based on the patient's history, preference, and other individual characteristics.

Selective serotonin reuptake inhibitors ( SSRIs ) selectively block the reuptake of serotonin ( 5-HT ) through their inhibiting effects on the sodium / potassium ATP-dependent serotonin transporter in presynaptic neurons.

* selective serotonin reuptake inhibitors ( SSRIs )

Of the various types of ADMs used to treat SAD, selective serotonin reuptake inhibitors ( SSRIs ) such as fluoxetine and sertraline appear to be most effective.

Fluoxetine ( Prozac ) and other selective serotonin reuptake inhibitors ( SSRIs ) have limited usefulness in treating trichotillomania, and can often have significant side effects.

* Many psychotropic medications, such as selective serotonin reuptake inhibitors ( SSRIs ), monoamine oxidase inhibitors ( MAOIs ), and tricyclic antidepressants, can cause hyperthermia.

Drugs affecting the central nervous system include: hypnotics, anaesthetics, antipsychotics, antidepressants ( including tricyclic antidepressants, monoamine oxidase inhibitors, lithium salts, and selective serotonin reuptake inhibitors ( SSRIs )), antiemetics, anticonvulsants / antiepileptics, anxiolytics, barbiturates, movement disorder ( e. g., Parkinson's disease ) drugs, stimulants ( including amphetamines ), benzodiazepines, cyclopyrrolones, dopamine antagonists, antihistamines, cholinergics, anticholinergics, emetics, cannabinoids, and 5-HT ( serotonin ) antagonists.

* Selective serotonin reuptake inhibitor anti-depressants ( SSRIs ), because of their serotonergic effect, would seem to help IBS, especially patients who are constipation predominant.

Medical interventions are primarily concerned with hormonal intervention and use of selective serotonin reuptake inhibitors ( SSRIs ).

Most clinical authors recommend a multifaceted or multimodal approach that includes a variety of treatments, including certain classes of anti-depressants ( selective serotonin reuptake inhibitors, or SSRIs ) that reduce sex drive in some people, motivational interviewing, and individual, group, or couples ' therapy ( including cognitive-behavioral, psychodynamic, and relapse-prevention ).

However, the most severe decreases in sexual desire relating to psychiatric medication occur due to the use of selective serotonin reuptake inhibitors ( SSRIs ).

A common cause of situational anorgasmia, in both men and women, is the use of anti-depressants, particularly selective serotonin reuptake inhibitors ( SSRIs ).