Significant progress in Big Bang cosmology have been made since the late 1990s as a result of advances in telescope technology as well as the analysis of data from satellites such as COBE, the Hubble Space Telescope and WMAP.

Significant progress has also been made in bringing the world of UML modeling and the Semantic Web together through the adoption of the Ontology Definition Metamodel which relates UML models in a standard way with RDF and Web Ontology Language ( OWL ) models.

Significant progress came following the work of Louis Pasteur and his advances in microbiology, when the British surgeon Joseph Lister began experimenting with using phenol during surgery to prevent infections.

Significant progress in science was made in the Muslim world during the Middle Ages, especially during the Islamic Golden Age, which is considered a major period in the history of science.

Significant progress is being made particularly in ecotourism.

Significant progress took place between Drep de kristne and Last Predators.

Significant progress in the study of Slavic mythology was made during the last 30 years, mostly through the work of the Russian philologists Vladimir Toporov and Vyacheslav Vsevolodovich Ivanov, as well as that of the Croatian scientists Radoslav Katičić and Vitomir Belaj.

Significant progress was achieved, and a haemoglobin-based oxygen therapeutic called Hemopure was approved for Phase III trial ( in elective orthopedic surgery ) in the U. S., and more widely approved for human use in South Africa.

Significant progress has been made in the care of premature infants, but not in reducing the prevalence of preterm birth.

Significant contributions to modern stapedectomy techniques were then made by the late Dr. Antonio De La Cruz of the House Ear Institute in Los Angeles ; by the late Professor Henri André Martin of the Hôpital Edouard Herriot in Lyon, France, including calibrated platinotomy ( stapes footplate rather than whole surgery ) and trans-footplate piston surgery that also paved the way for modern stapedotomy ; and by the late Dr. Jean-René Causse of the eponymous clinic in Béziers, France, who pioneered the use of Teflon piston prostheses ( also critical progress for stapedotomy ) and, with his late son Dr. Jean-Bernard Causse, the reattachment of the stapedius muscle alongside the use of veinous grafts.

Significant progress in alchemy was made in ancient India.

Significant progress is being made in raising FEL power levels ( the Thomas Jefferson National Accelerator Facility's FEL has demonstrated over 14 kW ) and it should be possible to build compact multi-megawatt class FEL weapons.

Significant further progress is expected to take place with the advent of nanotechnologies.

Significant economic and social progress was made, with an increase in foreign trade, the abolition of slavery and the expansion of education to the emerging middle class.

Significant progress has been made in understanding DNA methylation in the model plant Arabidopsis thaliana.

Significant progress in metallurgy and alchemy was made in ancient India.

Significant progress has been reported on polyphenols, particularly ellagic acid, tannins and anthocyanins, antioxidant activity, anti-cancer and anti-viral properties.

" Significant technical progress was made during 1994 on the CRAY-4, which takes advantage of technologies and manufacturing processes developed during the design and manufacture of the CRAY-3.

Significant collections of Tiffany windows outside the United States are the 17 windows in the former Erskine and American United Church, now part of the Montreal Museum of Fine Arts in Montreal, Canada, and the two windows in the American Church in Paris, on the Quai d ' Orsay, which have been classified as National Monuments by the French government ; these were commissioned by Rodman Wanamaker in 1901 for the original American Church building on the right bank of the Seine.

Significant numbers of Roma living in Czech orphanages did not have their legal status clarified, and were released from care as adult non-citizens without any right to work or live in the Czech Republic.

* Significant emotional pain caused by an event ( rather than a mental disorder ) can cause an individual to temporarily lose all interest in food

Significant dependence on foreign food producers makes a country strategically vulnerable in the event of war, blockade or embargo.

Significant elements of the two Massachusetts regiments, which were under the overall command of Colonel James Mercer of Pepperrell's Regiment, had overwintered there, and suffered significantly due to the shortage of supplies, especially food.

So, after the sitting has been held, several readings at one time are mailed, and the distant sitter ( whose name or whose communicator's name was given to the medium ) must mark each little item as Correct ( Hit ), Incorrect ( Miss ), Doubtful, or Especially Significant ( applying to him and, he feels, not to anyone else ).

The Comic Book in America: An Illustrated History ( Taylor Publishing: Dallas, Texas, 1989 ), pp. 178 – 181, reprinted at website Religious Affiliation of Comics Book Characters: " The Significant Seven: History's Most Influential Super-heroes " < nowiki >< nowiki ></ nowiki ></ ref >

Significant individual contributions to the war effort by Scots included the invention of radar by Robert Watson-Watt, which was invaluable in the Battle of Britain, as was the leadership at RAF Fighter Command of Air Chief Marshal Hugh Dowding.

Significant events in the early development of rugby football were the production of the first set of written football laws at Rugby School in 1845, which was followed by the ' Cambridge Rules ' drawn up in 1848.

Significant variants of the game, such as where the starting position differs from standard or the objective is to have the fewest pieces one's color at the end, are sometimes — but rarely — played.

# Significant duration: Continuous signs of the disturbance persist for at least six months.

Significant passages include the beloved Laus Italiae of Book 2, the prologue description of the temple in Book 3, and the description of the plague at the end of Book 3.

Significant operation success in Kosovo led to resumption of production and technical improvements, and the system is at present in operational use in Iraq and other military operations.

The Comic Book in America: An Illustrated History ( Taylor Publishing: Dallas, Texas, 1989 ), pp. 178 – 181, reprinted at website Religious Affiliation of Comics Book Characters: " The Significant Seven:

* Significant clinical discomfort or impairment at work, social situations, or other important life areas.

Significant change was achieved, although agencies never really achieved the level of autonomy envisaged at the start.

Significant excavation has since been conducted at the site of the city, which was designated a UNESCO World Heritage Site in 1980.

Significant pieces of the TX-0 are currently on display in the Library at Lincoln Laboratory.

Significant contributions to the war effort included the development in 1940 of the cavity magnetron for radar, by the scientists John Randall and Harry Boot, at the University of Birmingham, and advances in communications technology and the ongoing mass production of valves, lamps and lighting equipment.

Significant action was taken along the Gulf Coast as the threat the storm posed, predicted to come ashore at Category Four strength, became more urgent.

Significant outlying population growth is shown in the area ; the ZIP Code Tabulation Area for Hamilton's ZIP Code, 59840, had a population of 15, 393 at the United States Census Bureau 2009 estimate.

Significant beach erosion has occurred at the western end of Emerald Isle.

* Life is Beautiful at the Arts & Faith Top 100 Spiritually Significant Films list

Significant amendments may be made at committee stage.

Significant mutations were so imposed on the performing venues, on the way interpreters presented themselves, and on the sung repertoires-striped of any improvised character-cementing a professionalization process of several interpreters, instrument players, song writers and composers, who were then performing at several venues before an increasing audience.

Significant falls at Poulaphouca and at Golden Falls were flooded by reservoir construction.

Patients are assigned to MDC 24 ( Multiple Significant Trauma ) with at least two significant trauma diagnosis codes ( either as principal or secondaries ) from different body site categories.

Significant shear is observed when the temperature difference across the front is 5 ° C ( 9 ° F ) or more, and the front moves at 30 knots or faster.