Since the great flood of these dystopias has appeared only in the last twelve years, it seems fairly reasonable to assume that the chief impetus was the 1949 publication of Nineteen Eighty-Four, an assumption which is supported by the frequent echoes of such details as Room 101, along with education by conditioning from Brave New World, a book to which science-fiction writers may well have returned with new interest after reading the more powerful Orwell dystopia.

Since then and during the first decade, the results were given to newspapers for publication at 11 pm on the night of the awards.

Since conference and of the Food and Agriculture Organization's publication World Festival of Trees, and a resolution of the United Nations in 1954: " The Conference, recognising the need of arousing mass consciousness of the aesthetic, physical and economic value of trees, recommends a World Festival of Trees to be celebrated annually in each member country on a date suited to local conditions "; it has been adopted by the Netherlands.

Since the publication of Nineteen Eighty-Four, the term " Big Brother " has entered the lexicon as a synonym for abuse of government power, particularly in respect to civil liberties, often specifically related to mass surveillance.

Since the publication of Nineteen Eighty-Four the phrase " Big Brother " has come into common use to describe any prying or overly-controlling authority figure, and attempts by government to increase surveillance.

Since the Roman consular fasti make it somewhat easy to confuse 87 – 57 BC with 84 – 54 BC, many scholars accept the dates 84 BC – 54 BC, supposing that his latest poems and the publication of his libellus coincided with the year of his death.

Since the introduction of the comic book format in 1933 with the publication of Famous Funnies, the United States has produced the most titles, along with British comics and Japanese manga, in terms of quantity of titles.

Since her death in 1968 and the publication of her daughter Imogen's autobiography, A Childhood at Green Hedges, Blyton has emerged as an emotionally immature, unstable and often malicious figure.

Since their first publication, Goya's scenes of atrocities, starvation, degradation and humiliation have been described as the " prodigious flowering of rage ".

Since about 93 % of the data submitted to the FBI is in this format, the UCR stands out as the publication of choice as most states require law enforcement agencies to submit this data.

Since 1974 with the publication of Elizabeth A. R. Brown's The Tyranny of a Construct, and Susan Reynolds ' Fiefs and Vassals ( 1994 ), there has been ongoing inconclusive discussion among medieval historians as to whether feudalism is a useful construct for understanding medieval society.

Beyond its first verse, which is consistent, it has many historic and extant versions: Since its first publication, different verses have been added and taken away and, even today, different publications include various selections of verses in various orders.

Since its first publication in 1946 the principle has been accepted by Germany's Federal Constitutional Court in a variety of cases.

Since the publication of the History of Trade Unionism ( 1894 ) by Sidney and Beatrice Webb, the predominant historical view is that a trade union " is a continuous association of wage earners for the purpose of maintaining or improving the conditions of their employment.

Since the publication of this book, which has rarely been out of print since his death, Nostradamus has attracted a following that, along with much of the popular press, credits him with predicting many major world events.

Since then the publication of a series of world catalogues specializing in world phonecards, the hobby has had a new lease of life with people collecting as a hobby and for investment.

Since its publication, Rashi's commentary on the Torah is standard in almost all Chumashim produced within the Orthodox Jewish community.

Since the publication of Edward Said's Orientalism, the term has tended to acquire acquired a negative connotation, and in much academic discourse become shorthand for Western feelings of superiority over, and overlooking of the views of, Asian and North African cultures.

Since the publication of the two original documents, a number of additional Microsoft memoranda on related topics have also been leaked and published ( e. g. Halloween VII ).

Since 1975 it has been entitled The Garden and is currently a monthly publication.

Since its initial publication, the novel has never gone out of print.

Since the publication of the original books, several authors have used the Riverworld setting for their own stories.

Since that time, The Sentencing Project has become a leader in the effort to bring national attention to disturbing trends and inequities in the criminal justice system with a successful formula that includes the publication of groundbreaking research, aggressive media campaigns strategic advocacy for policy reform.

Since its publication, the prose style and dialogue in Hemingway's novel have been the source of controversy and some negative critical reaction.

Since the black rat now occupies the many of the micro-habitats that were previously inhabited by the bush rat, the black rat plays an important ecological role in the dispersal of fungal spores.

Since discovery by humans, numerous species have been introduced to the island, some deliberately, like the casurina, the feral pig, the Cardinal ( Cardinalis cardinalis ), anoles, ladybird beetles, and the Kiskadee, some incidentally, like the Norwegian rat ( Rattus norvegicus ) and the Black Rat ( Rattus rattus ), and the others accidentally, like the scale mites, and the brown widow spider ( Latrodectus geometricus ).

The use of a rat sequence also confirmed this topology and estimated date of divergence from the swine / human strains was 7. 44 × 10 < sup > 4 </ sup > years ago ( range 2. 1 × 10 < sup > 4 </ sup > to 1. 4 × 10 < sup > 5 </ sup > years ago ) Since this date is approximately coincident with the advent of agriculture it may be that this virus originally infected rats and subsequently spread to pigs and then to humans.

Since its first description in 1898, most authors have regarded it as a distinct species, but it has also been classified as a mere subspecies of the marsh rice rat ( O. palustris ).

Since native human amylin is highly amyloidogenic and potentially toxic, the strategy for designing pramlintide was to substitute residues from rat amylin, which is not amyloidogenic ( but would presumably retain clinical activity ).

Since genomes are very complex, one research strategy is to reduce the number of genes in a genome to the bare minimum and still have the organism in question survive.

Since excessive TE activity can destroy a genome, many organisms have developed mechanisms to inhibit this activity.

Since each cell, regardless of cell type, possesses the same genome, determination of cell type must occur at the level of gene expression.

Since the distribution of the defective mitochondrial DNA may vary from organ to organ within the body, and each mutation is modulated by other genome variants, the mutation that in one individual may cause liver disease might in another person cause a brain disorder.

The number of ncRNAs encoded within the human genome is unknown, however recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs .< sup >, but see </ sup > Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional.

After entering the hepatocyte, the virus is uncoated and the nucleocapsid translocated to the nucleus due to a signal in HDAg Since the nucleocapsid does not contain an RNA polymerase to replicate the virus ’ genome, the virus makes use of the cellular RNA polymerases Initially just RNA pol II, now RNA polymerases I and III have also been shown to be involved in HDV replication

Since the known ciliate mitochondrial genomes are considerably larger this reduction is genome size must have occurred after their ancestor of this clade diverged from that that gave rise to the extant ciliates.

Since these clones should cover the entire genome / chromosome, it is theoretically possible to assemble a contig of BACs that covers the entire chromosome.

Since these viruses have dsRNA genomes, replication occurs exclusively in the cytoplasm and the virus encodes several proteins which are needed for replication and conversion of the dsRNA genome into (+)- RNAs.

Since sequencing of the human genome which allowed rapid cloning and synthesis of large quantities of purified proteins, it has become common practice to use high throughput screening of large compounds libraries against isolated biological targets which are hypothesized to be disease modifying in a process known as reverse pharmacology.

Since the DNA introduced in the transfection process is usually not integrated into the nuclear genome, the foreign DNA will be diluted through mitosis or degraded.

Since the rabies virus has a linear – ssRNA genome, messenger RNAs are produced to permit virus replication using the host cell machinery.

* Task-nonspecificity: Since it is difficult for the genome to predict what tasks the baby will learn and perform in his life, the developmental program is body-specific ( species specific ) but not task-specific.

Since the publishing of the human genome, research carried out at the Institute has developed beyond sequencing of organisms into various biomedical research areas, including studies into diseases such as cancer, malaria and diabetes.

Since its integration as an institute into the EPFL School of Life Sciences on January 1st 2008 and the renewal of a substantial part of its scientific staff, its research focuses on areas including genome stability, cell proliferation and differentiation, and the role of developmental pathways in tumorigenesis and tumor progression.