The 2003 NICE ECT guidelines do not recommend ECT for schizophrenia, and this has been supported by meta-analytic evidence showing no or little benefit versus placebo, or in combination with antipsychotic drugs, including Clozapine.

This comes after NICE was ordered to pay Dictaphone $ 10 million in settlements related to a patent infringement suit in late 2003.

The source code for Noctis IV was released to the public in 2003, which has led to the creation of a fan-made " mod " to Noctis called Noctis IV CE ( commonly abbreviated NICE ).

NICE stated that long-term use of benzodiazepines for panic disorder with or without agoraphobia is an unlicensed indication, does not have long-term efficacy, and is, therefore, not recommended by clinical guidelines.

The UK's National Institute for Health and Clinical Excellence ( NICE ) guidelines recommend ECT for patients with severe depression, catatonia, or prolonged or severe mania.

In the UK, the NICE guidelines define infertility as failure to conceive after regular unprotected sexual intercourse for 2 years in the absence of known reproductive pathology.

In 2004, the British National Health Service's National Institute for Health and Clinical Excellence ( NICE ) considered a systematic review of four randomized controlled trials before issuing guidelines for the use of LASIK within the NHS.

Revised guidelines ( IPG164 ) were issued by NICE in March 2006, stating,

NICE publishes guidelines in three areas.

NICE was established in an attempt to defuse the so-called postcode lottery of healthcare in England and Wales, where treatments that were available depended upon the NHS Health Authority area in which the patient happened to live but it has since acquired a high reputation internationally as a role model for the development of clinical guidelines.

NICE have set up several National Collaborating Centres bringing together expertise from the royal medical colleges, professional bodies and patient / carer organisations which draw up the guidelines.

In its defence, NICE said the majority of its communications budget was spent informing doctors about which drugs had been approved and new guidelines for treatments and that the actual cost of assessing new drugs for the NHS includes money spent on NICE's behalf by the Department of Health.

Antibiotics are administered to patients with certain heart conditions as a precaution, although this practice has changed in the US, with new American Heart Association guidelines released in 2007, and in the UK as of March 2008 due to new NICE guidelines.

In many countries, including the UK, the majority view among endocrinologists is that the failure of treatment to provide any demonstrable, measurable benefits in terms of outcomes means treatment is not recommended for all adults with severe GHD, and national guidelines in the UK as set out by NICE suggest three criteria which all need to be met for treatment to be indicated:

In the UK NICE published guidelines and approval in November 2010.

An ASH report claims that the average cost per life year gained for every smoker successfully treated by these services is less than £ 1, 000, below the NICE guidelines of £ 20, 000 per QALY ( quality-adjusted life year ).

In the United Kingdom, clinical practice guidelines are published primarily by the National Institute for Health and Clinical Excellence ( NICE ).

In June 2006, the UK Advertising Standards Authority ( ASA ) upheld the complaint by NICE and ruled that the use of the quote was in breach of ASA guidelines.

National Institute for Health and Clinical Excellence ( NICE ) guidelines recommend that patients with moderate to severe ( 50-99 % blockage ) stenosis, and symptoms, should have " urgent " endarterectomy within 2 weeks.

The work that NICE is involved in attracts the attention of many groups, including doctors, the pharmaceutical industry, and patients.

The UK government organization NICE recently revised its recommendation favoring atypicals, to advise that the choice should be an individual one based on the particular profiles of the individual drug and on the patient's preferences.

Because of the weakness of the evidence and the potential for serious side effects from some drug therapies, the UK National Institute for Health and Clinical Excellence ( NICE ) 2009 clinical guideline for the treatment and management of BPD recommends: " Drug treatment should not be used specifically for borderline personality disorder or for the individual symptoms or behaviour associated with the disorder " but " drug treatment may be considered in the overall treatment of comorbid conditions ," and suggests " review of the treatment of people with borderline personality disorder who do not have a diagnosed comorbid mental or physical illness and who are currently being prescribed drugs, with the aim of reducing and stopping unnecessary drug treatment.

The name and mission was agreed in a meeting between the Ministerial team, Dr Tim Riley and Dr Felicity Harvey shortly after the election and it was agreed that NICE should be described in the first policy white paper, The New NHS: Modern, Dependable 1997

As a guideline rule, NICE accepts as cost effective those interventions with an incremental cost-effectiveness ratio of less than £ 20, 000 per QALY and that there should be increasingly strong reasons for accepting as cost effective interventions with an incremental cost-effectiveness ratio of over a threshold of £ 30, 000 per QALY.

In practice this exercise is not done, but an assumed shadow price has been used by NICE for many years in its assessments to determine which treatments the NHS should and should not fund.

NICE states that for drugs the cost per QALY should not normally exceed £ 30, 000 but that there is not a hard threshold, though research has shown that any threshold is " somewhat higher " than being in the range £ 35, 000-£ 40, 000.

Some witnesses, including patient organisations and pharmaceutical companies, thought NICE should be more generous in the cost per QALY threshold it uses, and should approve more products.

On the other hand, some PCTs struggle to implement NICE guidance at the current threshold and other witnesses argued that a lower level should be used.

However the Department of Health said that it has ' made it clear to PCTs that funding for treatments should not be withheld simply because guidance from NICE is unavailable '.

In April 2011 the UK's National Institute for Health and Clinical Excellence ( NICE ) recommended that women with symptoms that could be caused by ovarian cancer should be offered a CA-125 blood test.

However, the recent 2011 UK National Institute for Health and Clinical Excellence ( NICE ) guideline on the management of primary hypertension in adults ( CG127 ) recommend calcium channel blockers ( CCBs ) as first line agents in hypertension and advise that thiazide-like diuretics should only be used first line if CCBs are not suitable or if the patient has edema or has a high risk of developing heart failure.

In August 2010, the National Institute for Clinical Excellence ( NICE ) in the United Kingdom ruled that Xolair should not be prescribed on the National Health Service ( NHS ) to children under 12, causing widespread condemnation from asthma charities.

However NICE has recommended that there should be further research of CAT, for example in Borderline personality disorder.

According to National Institute for Health and Clinical Excellence ( NICE ), benzodiazepines can be used in the immediate management of GAD, if necessary.

The National Institute for Health and Clinical Excellence ( NICE ), UK released updated diabetes recommendations on the 30th May 2008, which recommend that self-monitoring of plasma glucose levels for people with newly diagnosed type 2 diabetes must be integrated into a structured self-management education process.

Opponents of the current reform care proposals fear that U. S. comparative effective research ( a plan introduced in the stimulus bill ) will be used to curtail spending and ration treatments, which is one function of NICE, arguing that rationing by market pricing rather by government is the best way for care to be rationed.

Palin had alleged that America will create rationing " death panels " to decide whether old people could live or die, again widely taken to be a reference to NICE.

The chief executive of the National Institute for Health and Clinical Excellence ( NICE ), told The Guardian newspaper that " it is neither true, nor is it anything you could extrapolate from anything we've ever recommended " that Kennedy would be denied treatment by the NHS.

NICE attempts to assess the cost-effectiveness of potential expenditures within the NHS to assess whether or not they represent ' better value ' for money than treatments that would be neglected if the expenditure took place.

The threshold it employs is not based on empirical research and is not directly related to the NHS budget, nor is it at the same level as that used by Primary Care Trusts ( PCTs ) in providing treatments not assessed by NICE, which tends to be lower.

NICE is often associated with controversy, because the need to make decisions at a national level can conflict with what is ( or is believed to be ) in the best interests of an individual patient.

But certain cancer drugs not approved by NICE because of cost will be available only if the patient is prepared to pay a co-pay to make up the difference in the NICE perceived value and the actual cost.

On November 10, 2011, Veolia and Mangano announced that the service was going to be renamed Nassau Inter-County Express ( or NICE ), upon Veolia's takeover of the system.

The transfers are valid for two hours and can be used on two connecting NICE routes.