The report author noted that electrical stimulation devices and weighted vaginal cones are not recommended by the UK National Institute for Clinical Excellence ( NICE ) and " are not universally advocated by clinicians as they have yet to produce sufficient evidence of efficacy ".

Some refractive surgeons in the United Kingdom and United States, including at least one author of a study cited in the report, proposed that NICE relied on information that was severely dated and weakly researched.

The House of Commons Health Select Committee, in its report on NICE, stated in 2008 that " the (...) cost-per-QALY it uses to decide whether a treatment is cost-effective is of serious concern.

An ASH report claims that the average cost per life year gained for every smoker successfully treated by these services is less than £ 1, 000, below the NICE guidelines of £ 20, 000 per QALY ( quality-adjusted life year ).

NICE concluded that the high costs of the compound, over £ 250 per vial, did not represent a sufficiently high increase in quality of life.

The NICE 2003 guidelines state that doctors should be particularly cautious when considering ECT treatment for women who are pregnant and for older or younger people, because they may be at higher risk of complications with ECT.

In April 2011 the UK's National Institute for Health and Clinical Excellence ( NICE ) recommended that women with symptoms that could be caused by ovarian cancer should be offered a CA-125 blood test.

Because of the weakness of the evidence and the potential for serious side effects from some drug therapies, the UK National Institute for Health and Clinical Excellence ( NICE ) 2009 clinical guideline for the treatment and management of BPD recommends: " Drug treatment should not be used specifically for borderline personality disorder or for the individual symptoms or behaviour associated with the disorder " but " drug treatment may be considered in the overall treatment of comorbid conditions ," and suggests " review of the treatment of people with borderline personality disorder who do not have a diagnosed comorbid mental or physical illness and who are currently being prescribed drugs, with the aim of reducing and stopping unnecessary drug treatment.

This is submitted to NICE who then formally approve the guideline and issues this guidance to the NHS.

The National Institute of Health and Clinical Excellence ( NICE ) suggests patients taking only one type of AEDs at a time.

The threshold it employs is not based on empirical research and is not directly related to the NHS budget, nor is it at the same level as that used by Primary Care Trusts ( PCTs ) in providing treatments not assessed by NICE, which tends to be lower.

On the other hand, some PCTs struggle to implement NICE guidance at the current threshold and other witnesses argued that a lower level should be used.

NICE is often associated with controversy, because the need to make decisions at a national level can conflict with what is ( or is believed to be ) in the best interests of an individual patient.

Wazuka's band of top tea farmers known as the Yukichaken and the local community are in cooperation with NICE one of the major volunteer program companies and hold together the biggest annual work camp at the end of August lasting 2 weeks.

In 2006 Mega launched the electric Mega City at the British International Motor Show and in 2009 acquired the assets of NICE Car Company, which went into administration in 2008.

* Narmada Infrastructure Construction Enterprise Limited ( NICE )-An SPV formed for design, construction, maintenance and operation of the 1. 4 km second Narmada bridge, including 4. 6 km of approach roads, on BOT basis on NH-8 at Zadeshwar, Gujarat.

Students may take courses at any of the local universities participating in the Northern Indiana Consortium for Education ( NICE )..

In 2007, after a comprehensive review of the literature, the UK's National Institute for Health and Clinical Excellence ( NICE ) expressed concern for the lack of quality evidence comparing the potential risks and benefits of home and hospital birthing environments.

The only medications NICE recommends for the longer term management of GAD are antidepressants.

But not all treatments have been assessed by NICE and these treatments are usually dependent on local NHS decision making.

All these are drugs with a high cost per treatment and NICE has either rejected or restricted their use in the NHS on the grounds that they are not cost-effective.

Dollar bills are not accepted on any NICE fixed-route buses.

The transfers are valid for two hours and can be used on two connecting NICE routes.

NICE stops are signed as follows.

Antibiotics are administered to patients with certain heart conditions as a precaution, although this practice has changed in the US, with new American Heart Association guidelines released in 2007, and in the UK as of March 2008 due to new NICE guidelines.

The terrain generation code has also been altered in the NICE version, which means that remarks made in the Noctis IV GUIDE are largely invalid for NICE.

These worlds are unlandable in the standard versions of Noctis, but in certain versions of NICE, landings for these worlds are being implemented.

However, the recent 2011 UK National Institute for Health and Clinical Excellence ( NICE ) guideline on the management of primary hypertension in adults ( CG127 ) recommend calcium channel blockers ( CCBs ) as first line agents in hypertension and advise that thiazide-like diuretics should only be used first line if CCBs are not suitable or if the patient has edema or has a high risk of developing heart failure.

In the United Kingdom, clinical practice guidelines are published primarily by the National Institute for Health and Clinical Excellence ( NICE ).

There is some question as to how well coordinated NICE and NHS are in making decisions about resource allocation.

In August 2008, following more than two-and-half-years of campaigning led by RNIB, the National Institute for Health and Clinical Excellence ( NICE ) issued new guidance on drugs for treating wet Age-related Macular Degeneration ( AMD ).

Some witnesses, including patient organisations and pharmaceutical companies, thought NICE should be more generous in the cost per QALY threshold it uses, and should approve more products.

Some of the more controversial NICE decisions have concerned donepezil, galantamine, rivastigmine ( review ) and memantine for the treatment of Alzheimer's disease and bevacizumab, sorafenib, sunitinib and temsirolimus for renal cell carcinoma.

A conservative shadow minister once criticized NICE for spending more on communications than assessments.

A more positive view of the benefits of Ezetimibe is offered by Britain's NICE statement which however was published in 2007 and may not have been updated to reflect the results of the above mentioned trials.

In the United Kingdom, as of January 2005, the ( NICE ) is believed to have a threshold of about £ 30, 000 per QALY – roughly twice the mean income after tax – although a formal figure has never been made public Thus, any health intervention which has an incremental cost of more than £ 30, 000 per additional QALY gained is likely to be rejected and any intervention which has an incremental cost of less than or equal to £ 30, 000 per extra QALY gained is likely to be accepted as cost-effective.

NICE stated that long-term use of benzodiazepines for panic disorder with or without agoraphobia is an unlicensed indication, does not have long-term efficacy, and is, therefore, not recommended by clinical guidelines.

NICE have set up several National Collaborating Centres bringing together expertise from the royal medical colleges, professional bodies and patient / carer organisations which draw up the guidelines.

For example the NHS usually pays for several rounds of treatment for fertility problems but because NICE has not assessed them some PCTs may cap the number of rounds and the patient may then have to pay privately if he or she wished to continue with fertility treatments beyond the capped level.

With the exception of landing on some world types ( being gas giants, Substellar Objects, and — although these have been made landable in NICE — unstable worlds ), this galaxy is entirely open to be explored.

The approach is too new for any systematic reviews of RCTs to have been conducted, and therefore is not yet explicitly recommended by name by the UK National Institute for Health and Clinical Excellence ( NICE ).

National Institute for Health and Clinical Excellence ( NICE ) guidelines recommend that patients with moderate to severe ( 50-99 % blockage ) stenosis, and symptoms, should have " urgent " endarterectomy within 2 weeks.