Amino acids (,, or ) are biologically important molecules made from amine (- NH < sub > 2 </ sub >) and carboxylic acid (- COOH ) functional groups, along with a side-chain specific to each amino acid.

Amino acids having both the amine and carboxylic acid groups attached to the first, or alpha, carbon atom have particular importance in biochemistry.

Amide are usually regarded as derivatives of carboxylic acids in which the hydroxyl group has been replaced by an amine or ammonia.

Another approach used is the reaction of di-functional monomers, with one amine and one carboxylic acid group on the same molecule:

Upon hydrolysis, an amide converts into a carboxylic acid and an amine or ammonia.

The carboxylic acid has a hydroxyl group derived from a water molecule and the amine ( or ammonia ) gains the hydrogen ion.

An amino acid contains both acidic ( carboxylic acid fragment ) and basic ( amine fragment ) centres.

These compounds contain an ammonium and a carboxylate group, and can be viewed as arising via a kind of intramolecular acid-base reaction: The amine group deprotonates the carboxylic acid.

Examples, such as bicine and tricine, contain a basic secondary or tertiary amine fragment together with a carboxylic acid fragment.

Examples include amino acids and proteins, which have amine and carboxylic acid groups, and self-ionizable compounds such as water and ammonia.

Aramids are generally prepared by the reaction between an amine group and a carboxylic acid halide group.

The amide derivatives that are obtained by Beckmann rearrangement can be transformed into a carboxylic acid by means of hydrolysis ( base or acid catalyzed ). And an amine by hoffman degradation of the amide in the presence of alkali hypoclorites at 80 degrees Celsius, the degradation is itself prone to side reactions namely, the formation of biurets or, cyanate polymers, To avoid this side reaction strict temperature control is necessary, the reaction must be conducted at sufficient temperature to isomerise the cyanate to the isocyante.

Acyl chlorides can be used to prepare carboxylic acid derivatives, including acid anhydrides, esters, and amides by reacting acid chlorides with: a salt of a carboxylic acid, an alcohol, or an amine respectively.

In contrast, both reactions involved in preparing esters and amides via acyl chlorides ( acyl chloride formation from carboxylic acid, followed by coupling with the alcohol or amine ) are fast and irreversible.

Aramids are generally prepared by the reaction between an amine group and a carboxylic acid halide group ( aramid ); commonly this occurs when an aromatic polyamide is spun from a liquid concentration of sulfuric acid into a crystallized fibre.

A permanganate can oxidize an amine to a nitro compound, an alcohol to a ketone, an aldehyde to a carboxylic acid, a terminal alkene to a carboxylic acid, oxalic acid to carbon dioxide, and an alkene to a diol.

The Ugi reaction is a multi-component reaction in organic chemistry involving a ketone or aldehyde, an amine, an isocyanide and a carboxylic acid to form a bis-amide.

Proline is the only proteinogenic amino acid whose side-group links to the α-amino group and, thus, is also the only proteinogenic amino acid containing a secondary amine at this position.

The general structure of an α-amino acid, with the amine | amino group on the left and the carboxyl group on the right.

For an amino acid with only one amine and one carboxyl group, the pI can be calculated from the mean of the pKas of this molecule.

Like other acid herbicides, current formulations use either an amine salt ( often trimethylamine ) or one of many esters of the parent compound.

The proper activity of these enzymes is crucial for the process of moving amine groups from one amino acid to another.

Acridine is easily oxidized by peroxymonosulfuric acid to the acridine amine oxide.

Its side-chain is an amide formed by replacing the side-chain hydroxyl of glutamic acid with an amine functional group making it the amide of glutamic acid.

Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group with an amine group.

* Iminodiacetic acid, a dicarboxylic acid amine

For example, silica is functionalized with an alkyl silicone, wherein the alkyl contains an amine functional group.

When the functional group attacking the peptide bond is a thiol, hydroxyl or amine, the resulting molecule may be called a cyclol or, more specifically, a thiacyclol, an oxacyclol or an azacyclol, respectively.

In chemistry, the sulfonamide functional group ( also spelt sulphonamide ) is-S (= O )< sub > 2 </ sub >- NH < sub > 2 </ sub >, a sulfonyl group connected to an amine group.

Aminoglycoside-modifying enzymes inactivate the aminoglycoside by covalently attaching either a phosphate, nucleotide, or acetyl moiety to either the amine or the alcohol key functional group ( or both groups ) of the antibiotic.

Usually, the gamma-emitting tracer used in functional brain imaging is < sup > 99m </ sup > Tc-HMPAO ( hexamethylpropylene amine oxime ).

The molecule has two amine groups (– NH < sub > 2 </ sub >) joined by a carbonyl functional group ( C = O ).

The Mannich reaction is an organic reaction which consists of an amino alkylation of an acidic proton placed next to a carbonyl functional group with formaldehyde and ammonia or any primary or secondary amine.

A hemiaminal is a functional group or type of chemical compound that has a hydroxyl group and an amine attached to the same carbon atom :-C ( OH )( NR < sub > 2 </ sub >)-.

An aminal or aminoacetal is a functional group or type of chemical compound that has two amine groups attached to the same carbon atom :-C ( NR < sub > 2 </ sub >)( NR < sub > 2 </ sub >)-.

A succinimidyl-ester functional group attached to the fluorescein core, creating NHS-fluorescein, forms another common amine reactive derivative that has much greater specificity toward primary amines in the presence of other nucleophiles.

It is unique among the 20 protein-forming amino acids in that the amine nitrogen is bound to not one but two alkyl groups, thus making it a secondary amine.

Reaction between a di-isocyanate and a compound containing two or more amine groups, produces long polymer chains known as polyureas.

The A-T and C-G pairings are required to match the hydrogen bonds between the amine and carbonyl groups on the complementary bases.

A catecholamine ( CA ) is an organic compound that has a catechol ( benzene with two hydroxyl side groups ) and a side-chain amine.

Catecholamines have the distinct structure of a benzene ring with two hydroxyl groups, an intermediate ethyl chain, and a terminal amine group.

Some ligands include the sulfate anion, the collagen's carboxyl groups, amine groups from the side chains of the amino acids, as well as " masking agents.

The amine ( NH ) groups react with the epoxide groups of the resin during polymerization.

When these compounds are mixed, the amine groups react with the epoxide groups to form a covalent bond.

Mercury is known to interfere with metabolism and function by combining with phosphoryl, carboxyl, amide and amine groups resulting in enzyme inhibition and protein precipitation.

This derivative is reactive towards primary amine groups of biologically relevant compounds including intracellular proteins to form a thiourea linkage.

A biogenic amine is a biogenic substance with one or more amine groups.

EDTA, ethylenediaminetetraacetic acid, has four carboxyl groups and two amine groups that can act as electron pair donors, or Lewis bases.

In this pH range, the amine groups remain protonated and thus unable to donate electrons to the formation of coordinate covalent bonds.