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Page "Stem cell" ¶ 30
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bone and marrow
He, and Mrs. Dalloway, too, had never permitted themselves the luxury of joys that dug into the bone marrow of the spirit.
In an attempt to reverse the downhill trend by stimulating the bone marrow and controlling any hemolytic component, triamcinolone, 16 mg. daily, was begun on Sept. 26, 1958, and continued until Feb. 18, 1959.
In a healthy individual, the number of CD4 + lymphocytes is in balance with the cells generated by the bone marrow ; however, in HIV-positive patients, this balance is lost due to an inability of the bone marrow to regenerate CD4 + cells.
The progression of the human immunodeficiency virus infection into AIDS is primarily due to the depletion of CD4 + T-helper lymphocytes in a manner that is too rapid for the body's bone marrow to replenish the cells, leading to a compromised immune system.
* Blood production — the marrow, located within the medullary cavity of long bones and interstices of cancellous bone, produces blood cells in a process called hematopoiesis.
* Fat storage — the yellow bone marrow acts as a storage reserve of fatty acids.
Filling the interior of the bone is the trabecular bone tissue ( an open cell porous network also called cancellous or spongy bone ), which is composed of a network of rod-and plate-like elements that make the overall organ lighter and allow room for blood vessels and marrow.
They are made up mostly of compact bone, with lesser amounts of marrow, located within the medullary cavity, and spongy bone.
Bone marrow can be found in almost any bone that holds cancellous tissue.
# Ex vivo, which means " outside the body " – Cells from the patient's blood or bone marrow are removed and grown in the laboratory.
As they do not have bone marrow, red blood cells are produced in the spleen and the epigonal organ ( special tissue around the gonads, which is also thought to play a role in the immune system ).
The molar teeth are strong in most species, allowing the animals to crack open bone to reach the marrow.
Recently, direct stem cell therapy of the heart muscle using bone marrow cell transplantation has been shown to dramatically reduce risks of heart failure in Chagas patients.
This means that chemotherapy also harms cells that divide rapidly under normal circumstances: cells in the bone marrow, digestive tract, and hair follicles.
Virtually all chemotherapeutic regimens can cause depression of the immune system, often by paralysing the bone marrow and leading to a decrease of white blood cells, red blood cells, and platelets.
In very severe myelosuppression, which occurs in some regimens, almost all the bone marrow stem cells ( cells that produce white and red blood cells ) are destroyed, meaning allogenic or autologous bone marrow cell transplants are necessary.

bone and stem
Or against her back, pressed on the column of vertebrae, which held her so magnificently straight and unyielding, until the segments of bone made tiny sharp cracking noises, like the snapped stem of a tulip.
But some stem cells migrate to where they are needed, such as mesenchymal stem cells which can migrate from the bone marrow to form e. g. muscle, bone or adipose tissue.
In 2007 and 2008, a man being treated by Gero Hütter was cured of HIV by repeated Hematopoietic stem cell transplantation ( see also Allogeneic stem cell transplantation, Allogeneic bone marrow transplantation, Allotransplantation ) with double-delta-32 mutation which disables the CCR5 receptor ; this cure was not completely accepted by the medical community until 2011.
Haematopoietic stem cells ( HSCs ) reside in the medulla of the bone ( bone marrow ) and have the unique ability to give rise to all of the different mature blood cell types.
For the stem cells and other undifferentiated blood cells in the bone marrow, the determination is generally explained by the determinism theory of haematopoiesis, saying that colony stimulating factors and other factors of the haematopoietic microenvironment determine the cells to follow a certain path of cell differentiation.
This type of aberration in a dividing stem cell in the bone marrow leads to adult leukemia
A 2006 article from the Whitehead Institute for Biomedical Research indicates that PrP expression on stem cells is necessary for an organism's self-renewal of bone marrow.
Highly plastic adult stem cells are routinely used in medical therapies, for example in bone marrow transplantation.
For example, the defining test for a bone marrow or hematopoietic stem cell ( HSC ) is the ability to transplant one cell and save an individual without HSCs.
Adult stem cell treatments have been successfully used for many years to treat leukemia and related bone / blood cancers through bone marrow transplants.
A number of adult stem cell therapies already exist, particularly bone marrow transplants that are used to treat leukemia.
Cells in the thymus can be divided into thymic stromal cells and cells of hematopoietic origin ( derived from bone marrow resident hematopoietic stem cells ).
* in bone marrow and stem cell transplantation
Five different and diverse types of leukocytes exist, but they are all produced and derived from a multipotent cell in the bone marrow known as a hematopoietic stem cell.
An oncology Intensive Care Unit is the only Peninsula facility to provide stem cell and autologous bone marrow transplants.

bone and cell
Osteoblasts are the immature bone cells, and eventually become entrapped in the bone matrix to become osteocytes-the mature bone cell.
One of the main things that distinguishes the matrix of a bone from that of another cell is that the matrix in bone is hard.
Osteoblasts and osteoclasts, coupled together via paracrine cell signalling, are referred to as bone remodeling units.
For example, bone morphogenic proteins stimulate bone cell differentiation, while fibroblast growth factors and vascular endothelial growth factors stimulate blood vessel differentiation ( angiogenesis ).
Production of Hb continues in the cell throughout its early development from the proerythroblast to the reticulocyte in the bone marrow.
The ability of the bone marrow to regulate the quantity of different cell types to be produced is more accurately explained by a stochastic theory: Undifferentiated blood cells are determined to specific cell types by randomness.
By regulating this balance between different cell types, the bone marrow can alter the quantity of different cells to ultimately be produced.
Osteoclast, with bone below it, showing typical distinguishing characteristics: a large cell with multiple nuclei and a " foamy " cytosol.

bone and quantity
In hypogonadal men testosterone has been shown to give improvement in bone quantity and quality, but, as of 2008, there are no studies of the effects on fractures or in men with a normal testosterone level.
In hypogonadal men testosterone has been shown to improvement bone quantity and quality, but, there are no studies looking at its effect on fracture risk or in men with a normal testosterone level.
This method, which often uses punches made from bone or antler tines ( or, among modern hobbyists, copper punches or even nails ), provides a greater means of controlling the direction and quantity of the applied force than when using even the most careful percussive flaking.
Another miracle accepted as proved in the same year was the multiplication of the bone dust of the saint, which provided for hundreds of reliquaries without the original amount experiencing any decrease in quantity.
For example, toothmarks on cave bear remains in areas where cave bears are the only recorded potential carnivores suggests occasional cannibalistic scavenging, possibly on individuals that died during hibernation, and dental microwear analysis indicates the cave bear may have fed on a greater quantity of bone than its contemporary, the smaller Eurasian brown bear.
The surgeon replaces missing parts with tissue of like quality and quantity ; nasal lining with mucosa, cartilage with cartilage, bone with bone, and skin with skin that best match the native skin color and skin texture of the damaged nasal subunit.
*# Clonal plasma cells > 10 % on bone marrow biopsy or ( in any quantity ) in a biopsy from other tissues ( plasmacytoma )
Unlike conventional dental implants, Mini dental implants may be loaded immediately and still have a high survival rate ( 94 %).< ref > The amount of time required to place an implant will vary depending on the experience of the practitioner, the quality and quantity of the bone and the difficulty of the individual situation.
Dental implant success is related to operator skill, quality and quantity of the bone available at the site, and the patient's oral hygiene.
In spite of its appearance, the mummy proved to be a mass of fragrant resin, containing a quantity of disordered bone.
A great number of objects have been found buried in the mud amongst the piles, consisting of implements of stone and bone, such as hatchets, chisels, needles, awls, besides a vast quantity of the bones of animals.

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