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The extramitochondrial localization of cytochrome c was shown to be specific as it was completed abolished upon adsorption of the primary antibody with the purified cytochrome c. The presence of cytochrome-c outside of mitochondria at specific location under normal physiological conditions raises important questions concerning its cellular function and translocation mechanism.
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extramitochondrial and localization
Besides cytochrome c, extramitochondrial localization has also been observed for large numbers of other proteins including those encoded by mitochondrial DNA.
Besides cytochrome c oxidase subunits, extramitochondrial localization has also been observed for large numbers of other mitochondrial proteins., This raises the possibility about existence of yet unidentified specific mechanisms for protein translocation from mitochondria to other cellular destinations.
extramitochondrial and cytochrome
However, detailed immunoelectron microscopic studies with rat tissues sections employing cytochrome c-specific antibodies provide compelling evidence that cytochrome-c under normal cellular conditions is also present at extramitochondrial locations.
The extramitochondrial function of these cytochrome c oxidase subunits has not yet been characterized.
extramitochondrial and be
In the higher organisms the clusters are therefore transported out of the mitochondrion to be incorporated into the extramitochondrial enzymes.
extramitochondrial and .
Of these 3 subunits encoded by mitochondrial DNA, two have been identified in extramitochondrial locations.
localization and was
Another example is in the Game Boy Advance game Mega Man Zero 3, in which one of the bosses, called Hellbat Schilt in the Japanese and European releases, was renamed Devilbat Schilt in the North American localization.
The localization of function hypothesis was supported by observations of epileptic patients conducted by John Hughlings Jackson, who correctly inferred the organization of the motor cortex by watching the progression of seizures through the body.
A rough localization was attempted by reconstructing the names of plants and animals ( importantly the beech and the salmon ) as well as the culture and technology ( a Bronze Age culture centered on animal husbandry and having domesticated the horse ).
In addition to genetic fingerprinting, RFLP was an important tool in genome mapping, localization of genes for genetic disorders, determination of risk for disease, and paternity testing.
However, this generalization was statistical and was not approved of by de Broglie, who said " that the particle must be the seat of an internal periodic movement and that it must move in a wave in order to remain in phase with it was ignored by the actual physicists are wrong to consider a wave propagation without localization of the particle, which was quite contrary to my original ideas.
In this localization process, local culture and history was promoted over a pan-China viewpoint.
The Bentuhua or localization / indigenization movement was sparked in the mid-1970s with the growing expression of ethnic discontent due to unequal distribution of political and cultural power between mainlanders and Taiwanese people.
* Jambo OpenOffice, was an localization project for a translated version in Swahili.
In Super Mario 64 and the English version of Mario Kart 64, Peach was voiced by Leslie Swan, a localization manager for Nintendo of America.
This was the first anatomical proof of the localization of brain function.
Initially, Franz Joseph Gall ( 1758 – 1828 ) claimed his very popular theory of Phrenology and localization of function in the brain, but it was attacked by Pierre Flourens ( 1794 – 1867 ) who claimed that, by careful ablation of various brain regions, he had disproved Gall's hypotheses.
However, it was Broca, not Aubertin, who finally put the localization of function existence issue to rest.
Thus, in practice quality was usually very poor, though the actual localization and translation were closer to a professional level than those found in modern fansubs.
Its name was changed from Zenigame to Squirtle during the English localization of the series in order to give it a " clever and descriptive name.
So, different functions could indeed be ascribed to particular regions of the brain, but that a finer localization was lacking.
It was originally released in Japan in, with an English language localization released for the North American market in.
Research published in 2005 has suggested that children and adults can benefit from bilateral cochlear implants in order to aid in sound localization and speech understanding, and a 2011 study indicated that the language skills of children with two implants was within the normal range for the age.
One part of the localization process was to create original art and components.
Under Lee, Taiwan underwent a process of localization in which local culture and history was promoted over a pan-China viewpoint.
Although the game's localization and translation was finished a year earlier, the game was ultimately deemed unprofitable for a fall 1991 North American release, and the planned release was canceled after the game had already been translated and all packaging and advertising was ready.
localization and shown
Most thylakoid proteins encoded by a plant's nuclear genome need two targeting signals for proper localization: An N-terminal chloroplast targeting peptide ( shown in yellow in the figure ), followed by a thylakoid targeting peptide ( shown in blue ).
A dual detector head gamma camera combined with a CT scanner, which provides localization of functional SPECT data, is termed a SPECT / CT camera, and has shown utility in advancing the field of molecular imaging.
Vibrissae have been shown to be required for, or to contribute to: object localization, orienting of the snout, detection of movement, texture discrimination, shape discrimination.
Electron microscopic studies made from the 1970s have shown the intracellular, although extracytoplasmic localization of Cryptosporidium species.
Although the game was shown at E3 2003 in English and a North American localization seemed likely, the game remained exclusive to Japan.
A March 2012 study conducted in Europe, in which minuscule electronic localization devices were fixed on bees, has shown that, even with very low levels of pesticide in the bee's diet, a high proportion of bees ( more than one third ) suffers form orientation disorder and is unable to come back to the hive.
5-aminosalicylate ( ASA ) has been shown to reduce β-catenin and its localization to the nucleus in colon cancer cells isolated from and in patients.
localization and be
The concentration and apparent localization of the WTV antigen in pseudophloem tissue of the tumor may indicate that the virus preferentially multiplies in the phloem and may need to be directly placed in this tissue in order to infect plants.
In 1989, the ILAE proposed a classification scheme for epilepsies and epileptic syndromes .< ref name =" ILEA1989 "> This can be broadly described as a two-axis scheme having the cause on one axis and the extent of localization within the brain on the other.
The principle becomes quite complex, however, given the uncertainties of fossilization, the localization of fossil types due to lateral changes in habitat ( facies change in sedimentary strata ), and that not all fossils may be found globally at the same time.
Ion channels may be classified by the nature of their gating, the species of ions passing through those gates, the number of gates ( pores ) and localization of proteins.
Cytoplasmic localization of mRNA is thought to be a function of the 3 ' UTR.
Any cargo with a nuclear localization signal ( NLS ) exposed will be destined for quick and efficient transport through the pore.
Alternative systems can be used with floor plan instead of maps for indoor robots, combined with localization wireless hardware.
For example, immunohistochemistry usually utilizes an antibody to one or more proteins of interest that are conjugated to enzymes yielding either luminescent or chromogenic signals that can be compared between samples, allowing for localization information.
PET imaging with FDG can also be used for localization of seizure focus: A seizure focus will appear as hypometabolic during an interictal scan.
While the encoding default for HTML pages served as XML is required to be UTF-8, the encoding default for a regular Web page ( that is: for HTML pages serialized as ) varies depending on the localization of the browser.
XML Localisation Interchange File Format ( XLIFF ) is intended to provide a single interchange file format that can be understood by any localization provider.
Core Data supports fetched properties ; multiple configurations within a managed object model ; local stores ; and store aggregation ( the data for a given entity may be spread across multiple stores ); customization and localization of property names and validation warnings ; and the use of predicates for property validation.
Those metadata can be attached automatically ( timecode, localization, take number, name of the clip ) or manually ( players names, characters, in Sports: red card, goal ...).
The spatial resolution of this procedure is limited by the plasmon localization and is about 1 nm, meaning that spatial thickness maps can be measured in scanning transmission electron microscopy with ~ 1 nm resolution.
Nevertheless, not all cues required for exact localization of the sound sources can be preserved this way, but it works also well for loudspeaker reproduction.
Many standard fluorescent dyes like GFP, Alexa dyes, Atto dyes, Cy2 / Cy3 and fluorescein molecules can be used for localization microscopy, provided certain photo-physical conditions are present.
3D super resolution microscopy with standard fluorescent dyes can be achieved by combination of localization microscopy for standard fluorescent dyes SPDMphymod and structured illumination SMI.
The support of multiple languages by computer systems can be considered a continuum between localization (" L10n "), through multilingualization ( or " m17n "), to internationalization (" i18n ").
Second, because all the pictures and text were stored separately in a resource fork, it could be used to allow a non-programmer to translate an application for a foreign market, a process called internationalization and localization.
If a precise localization is requested, we need a filter of small width in the signal domain and, via the uncertainty principle, its width in the frequency domain cannot be arbitrary small.
Additionally, literals can and should be externalized into resource files / scripts where possible, to facilitate localization of software if it is intended to be deployed in different regions.
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