* The chronically high levels of circulating neuroendocrine hormones such as catecholamines, renin, angiotensin, and aldosterone affects the myocardium directly, causing structural remodelling of the heart over the long term.

If the renin – angiotensin – aldosterone system is too active, blood pressure will be too high.

* Disease states that lead to abnormally high aldosterone levels can cause hypertension and excessive urinary losses of potassium.

Conn syndrome ( mineralcorticoid excess ) is marked by high blood pressure which can result in headache and hypokalemia ( low serum potassium, which can in turn produce muscle weakness, confusion, and palpitations ) low plasma renin activity, and high serum aldosterone.

Findings in Conn syndrome include low serum potassium, low plasma renin activity, and high serum aldosterone.

Stenosis of the renal arteries, causes hypoperfusion ( decreased blood flow ) of the juxtaglomerular apparatus, resulting in exaggerated secretion of renin, and high blood levels of aldosterone, eventually leading to water and salt retention and high blood pressure.

The response of the kidney to this perceived decreased blood pressure is activation of the renin-angiotensin aldosterone system, which normally counteracts low blood pressure but in this case leads to hypertension ( high arterial blood pressure ).

The artist, unlike the philosopher, is not a removed observer aiming at neutral and rarified high levels of abstraction.

It can be seen too that when we contrast levels of compulsivity within the structured schools, the high compulsive children do better ( Af ).

My answer is in the negative because I believe that total capital demands during the Sixties will continue to press against available supplies, and interest rates will generally tend to be firm at high levels.

It will be shown theoretically that the high image intensification obtainable with such a tube and contact photography permits the utilization of extremely low incident light levels.

It is obvious that such an influence can only be expected in the final stage of an image intensifier at rather high output levels.

In tropical and other climates typified by hot days and cool nights, the high thermal mass of adobe levels out the heat transfer through the wall to the living space.

Exposure to high levels of methylmercury, through consumption of fish with high mercury concentrations, is also a known cause of ataxia and other neurological disorders.

The food also has a reputation for high levels of MSG to enhance the flavor.

According to the Fraser Institute, Alberta has very high levels of economic freedom and rates Alberta as the most free economy in Canada, and second most free economy amongst U. S. states and Canadian provinces.

These nurture high levels of phytoplankton with associated copepods and krill, and resultant foodchains supporting fish, whales, seals, penguins, albatrosses and a wealth of other species.

The toasts vary by group, and some groups make a distinction between a " regular " sumbel and a " high " sumbel, which have different levels of formality, and different rules during toasting.

Along with some of the other major Coalition cities, Chi-Town is considered a " Mega-City " in that its entire population is housed inside one giant structure consisting of more than thirty levels, each of which are several stories high and contain a number of sub-levels.

Fire breaks out and spreads in downtown Grand Forks, but high water levels hamper efforts to reach the fire, leading to the destruction of 11 buildings.

Produced in the cortex, cortisol reaches the adrenal medulla and at high levels, the hormone can promote the upregulation of phenylethanolamine N-methyltransferase ( PNMT ), thereby increasing epinephrine synthesis and secretion.

In the 1970s, high levels of dioxin were found in the breast milk of South Vietnamese women, and in the blood of U. S. soldiers who had served in Vietnam.

Some of the soil and sediment on the bases have extremely high levels of dioxin requiring remediation.

Class B amplifiers have a very high efficiency but are impractical for audio work because of high levels of distortion ( See: Crossover distortion ).

Bluetooth is a proprietary open wireless technology standard for exchanging data over short distances ( using short-wavelength radio transmissions in the ISM band from 2400 – 2480 MHz ) from fixed and mobile devices, creating personal area networks ( PANs ) with high levels of security.

In cattle, goats and wild ruminants infection is usually asymptomatic despite high virus levels in blood.

The two remaining non-structural proteins, NS1 and NS2, are produced at high levels in the cytoplasm and are believed to be involved in virus replication, assembly and morphogenesis.

During this period he instituted a regime of continuous training and insisted on high levels of physical fitness for both officers and other ranks.

At high levels of play, especially in singles, the sport demands excellent fitness: players require aerobic stamina, agility, explosive strength, speed and precision.

At high levels of play, the backhand serve has become popular to the extent that forehand serves have become fairly rare at a high level of play.

The causes of the decline of the commuter railroads are many and complex -- high taxes, losses of revenue to Government subsidized highway and air carriers, to name but two.

i.e., high loop gain causes the system to respond to horizontal components of accelerations.

Non-hereditary causes of cerebellar degeneration include chronic ethanol abuse, paraneoplastic cerebellar degeneration, high altitude cerebral oedema, coeliac disease, normal pressure hydrocephalus and cerebellitis.

The reaction works because the high electron density at the double bond causes a temporary shift of electrons in the Br-Br bond causing a temporary induced dipole.

This population density, high for Africa, causes annual migrations of hundreds of thousands of Burkinabé to Côte d ' Ivoire and Ghana for seasonal agricultural work.

In sheep BTV causes an acute disease with high morbidity and mortality.

Engaging the clutch abruptly when the engine is turning at high speed causes a harsh, jerky start.

With the complex sensory reaction to the variety of spices and flavours, a natural high is achieved that causes subsequent cravings, often followed by a desire to move on to hotter curries.

For example, high glycine concentration disrupts temperature and blood pressure control, and high CSF pH causes dizziness and syncope .. To use Davson's term, the CSF has a " sink action " by which the various substances formed in the nervous tissue during its metabolic activity diffuse rapidly into the CSF and are thus removed into the bloodstream as CSF is absorbed.

This system though is not very reliable and lacks discipline, the high number of public cars that transit the roads, and the fact that they do not lend itself to regulation or central control, which causes frequent transit problems among city roads.

They can also be affected by high concentrations of other macromolecules, which causes macromolecular crowding.

** coathanger – slang for high contact to the head, usually by a stiff arm, which causes a player to land flat on their back.

Generalized hypoxia occurs in healthy people when they ascend to high altitude, where it causes altitude sickness leading to potentially fatal complications: high altitude pulmonary edema ( HAPE ) and high altitude cerebral edema ( HACE ).

The immune system response to a microorganism often causes symptoms such as a high fever and inflammation, and has the potential to be more devastating than direct damage caused by a microbe.

As the nuclear warhead reenters the Earth's atmosphere its high speed causes compression of the air, leading to a dramatic rise in temperature which would destroy it if it were not shielded in some way.

An office building is illuminated by sodium lamp | high pressure sodium ( HPS ) lamps shining upward, of which much light goes into the sky and neighboring apartment blocks and causes light pollution, in Nijmegen, the Netherlands.

The main causes are special requirements for service and repair ( mostly available only in Moscow & Togliatti ) and very high fuel & lubricating oil consumption.

The main causes for these declines are the high cost of transportation, a lack of fuels, and the poor state of Moldova's transportation infrastructure: approximately 20 percent of Moldova's roads are considered in a critical technical state.

Some physicians also choose methadone for treating chronic pain in patients who are thought to have a propensity for addiction, because it causes less of an intoxicated or euphoric " high ".

In fact, injection of methadone does not result in a " rush " as with some other strong opioids such as morphine or hydromorphone, because its extraordinarily high volume of distribution causes it to diffuse into other tissues in the body, particularly fatty tissue ; the peak concentration in the blood is achieved at roughly the same time, whether the drug is injected or ingested.

The high temperatures coupled with an increase in insolation causes a region of low pressure to develop over west Africa and Nigeria ( between March to May ).

While the exposure of the wheels to the airstream causes a very high aerodynamic drag at high speeds, it allows improved cooling of the brakes, which is important on road courses with their frequent changes of pace.