The large and diverse population of antibodies is generated by random combinations of a set of gene segments that encode different antigen binding sites ( or paratopes ), followed by random mutations in this area of the antibody gene, which create further diversity.

The effects of glaciation include a number of large lakes and a relatively low diversity of freshwater fish.

Although large cities are also municipalities, they are often thought of as a collection of communities, due to their diversity.

The reference to Passover twice in the same year might refer to the geographical diversity that existed at that time in the Jewish calendar, due in large measure to the breakdown of communications in the Empire.

The Polygalaceae is fairly well researched among plant families, in part due to the large diversity of the genus Polygala, and also due to members of the family, like the Fabaceae, being food plants for various Lepidoptera ( butterfly and moth ) species.

They comprise a large number of secondary metabolites and natural products from animal, plant, bacterial, fungal and marine sources, and have great structural diversity.

If there were a large ( possibly infinite ) number of universes, each with possibly different physical laws ( or different fundamental physical constants ), some of these universes, even if very few, would have the combination of laws and fundamental parameters that are suitable for the development of matter, astronomical structures, elemental diversity, stars, and planets that can exist long enough for life to emerge and evolve.

Structures and a large diversity of physical and chemical properties is available for each substance, with reference to original literature.

The combination of tropical latitude, mountain ranges, topography variations and two ocean currents ( Humboldt and El Niño ) gives Peru a large diversity of climates.

Control over party history and the legal status of individual ex-party members played a large role in dictating the ideological diversity and thus the faction in power within the CPSU.

Even though natural product drug discovery has not probably been the most fashionable trend in pharmaceutical industry in recent times, a large proportion of new chemical entities still are nature-derived compounds, and thus, it has been suggested that effectiveness of combinatorial chemistry could be improved by enhancing the chemical diversity of screening libraries.

Despite the limited diversity of species, the number of individuals is large.

The region's ethnic diversity has been affected by repeated waves of immigrant workers from abroad: Belgians before 1910 ; Poles and Italians in the 1920s and 1930s ; Italians and Germans since 1945 and North Africans and Portuguese since 1960 ; and large cities like Lille, Calais, and Boulogne are home to sizable communities of British, Dutch, Scandinavian, Sub-Saharan African, and Latin American immigrants and their descendants.

Madagascar holds great potential for agricultural development, mainly due to the large variety of soil types and climatic diversity.

Serbs have great passion for food in general, especially barbecue, having a rich cuisine and a large diversity of alcohol beverages that accompany these fat-rich dishes.

At one point, the land mass of Bermuda was about, large enough to allow the genetic diversity for many plants and animals that established themselves to develop into unique species and sub-species.

Recently, a large fossil ziphiid sample was discovered off the South African coast, confirming the extant ziphiid diversity might just be a remnant of a higher past diversity.

This diversity results in complex food webs, with large predator fish eating smaller forage fish that eat yet smaller zooplankton and so on.

The genus has a large genetic diversity, and can grow from anywhere between 15 – 50 m ( 50 to 165 ft ) tall, with trunks of up to 2. 5 m ( 8 ft ) diameter.

In recent years, to fight the loss of regional diversity, many in France have promoted forms of multiculturalism and encouraged cultural enclaves ( communautarisme ), including reforms on the preservation of regional languages and the decentralization of certain government functions, but French multiculturalism has had a harder time of accepting, or of integrating into the collective identity, the large non-Christian and immigrant communities and groups that have come to France since the 1960s.

The road down to the river shows the diversity of flora as you drop in elevation and visitors can experience groves of Native Hibiscus ( Hibiscus heterophyllus ) and get to see river bank terraces shaded with large, Fuzzy Box ( Eucalyptus conica ).

The variety of habitats within Wollemi National Park allow for large diversity in animals.

Carrboro is a favorite destination of UNC students for its relatively large number and diversity of restaurants.

There is a large variety of models to choose from in most countries, however, including 6-passenger sedans and station wagons and the rental fee isn't all that much greater than for the wee sedans.

A modern cotton gin plant costs in the neighborhood of $250,000, and it's a safe assumption that a large percentage of new gins in the U.S. and foreign countries contain machinery made in this area.

A multitude of airports around the Alps ( and some within ), as well as long-distance rail links from all neighbouring countries, afford large numbers of travellers easy access from abroad.

Although amaranth was cultivated on a large scale in ancient Mexico, Guatemala, and Peru, nowadays it is only cultivated on a small scale there, along with India, China, Nepal, and other tropical countries ; thus, there is potential for further cultivation in those countries, as well as in the U. S. In a 1977 article in Science, amaranth was described as " the crop of the future.

In many countries, including much of the United States, bow hunting for large and small game is legal.

Dozens of large cities and hundreds of towns reflect pronounced urban character of the Arab world ; in most of the countries about 70 percent of people are urban dwellers.

Likewise, Joseph E. Stiglitz, speaking not only on China but East Asia in general, comments " The countries that have managed globalization ... such as those in East Asia, have, by and large, ensured that they reaped huge benefits ..." According to The Heritage Foundation, development in China was anticipated by Milton Friedman, who predicted that even a small progress towards economic liberalization would produce dramatic and positive effects.

Some doubts have been raised about the long-term effectiveness of antipsychotics for schizophrenia, in part because two large international World Health Organization studies found individuals diagnosed with schizophrenia tend to have better long-term outcomes in developing countries ( where there is lower availability and use of antipsychotics and mental health problems are treated with more informal, community-led methods only ) than in developed countries.

A large portion of its nearly 2, 000 T-55 tanks fell into disrepair, and eventually almost all of them were scrapped or sold to other countries.

The rationale behind this treaty, which has been ratified or acceded to by 165 countries as of 2011, is to prevent a biological attack which could conceivably result in large numbers of civilian fatalities and cause severe disruption to economic and societal infrastructure.

He found that material was scattered over an area in diameter, and in addition to military and nautical equipment recovered a large number of gold and silver coins from countries across the Mediterranean, some from the seventeenth century.

In the 1950s, Cuba's gross domestic product ( GDP ) per capita was roughly equal to that of contemporary Italy, and significantly higher than that of countries such as Japan, although Cuba's GDP per capita was still only a sixth as large as that of the United States.

Such devices are required by environmental legislation for cars in most countries, and may be necessary in large combustion devices, such as thermal power stations, to reach legal emission standards.

Most countries control bank mergers and are wary of concentration in this industry due to the danger of groupthink and runaway lending bubbles based on a single point of failure, the credit culture of the few large banks.

This also brought a large wave of immigrants from European and Middle Eastern countries.

Because growing vegetation absorbs carbon dioxide, the Kyoto Protocol allows Annex I countries with large areas of growing forests to issue Removal Units to recognise the sequestration of carbon.

The age structure of the population of Comoros is similar to that of many developing countries, in that the republic has a very large proportion of young people.

In both countries, grand coalitions of the two large parties also occur, but these are relatively rare and large parties usually prefer to associate with small ones.

This is most common amongst Nordic countries but requires a large number of different registers to be combined including population, housing, employment and education.

In Europe, in connection with the 2010 census round, a large number of countries adopted alternative census methodologies, often based on the combination of data from registers, surveys and other sources.

In the U. S., large scale cranberry cultivation has been developed as opposed to other countries.

However, in several European countries with civil law, as opposed to the Anglo-American common law system, changes have been made in recent years that allow consumer organizations to bring claims on behalf of large groups of consumers.