Prescribing opioids or amphetamines for depression falls into a legal grey area.

The final Big Dig plan, then, combined several projects — the depression and improvement of the Central Artery, the construction of a third Harbor tunnel ( now known as the Ted Williams Tunnel ), and massive interchange improvements to the Massachusetts Turnpike and several other major routes in the area.

Much of eastern Mongolia is occupied by a plain, and the lowest area is a southwest-to-northeast trending depression that reaches from the Gobi Desert region in the south to the eastern frontier.

Moncton's economic depression did not last long and a second era of prosperity came to the area in 1871 when Moncton was selected to be the headquarters of the Intercolonial Railway of Canada ( ICR ).

In animal models of depression, particularly " learned helplessness " and " social defeat ", there is evidence of pruning of normally dense synaptic connections in the hippocampus, a richly connected area deep in the temporal lobe which is vital in controlling both mood and memory.

The depression has the form of a teardrop with the point of the drop facing east and the broad deep area facing the south west.

Taiga and tundra in the north, swampy forest in the central depression, and deciduous forest in the south are the natural vegetation in the area.

* Roger & Me ( 1989 ) Documentary about the economic depression in the Flint area caused by the closure of several General Motors factories in the late 1980s.

Farm products lost some 75 percent of their value during the depression, which the area state representative, Oscar Callaway, blamed primarily on the Federal Reserve System.

The buried vegetation began to release methane gas ( a byproduct of decomposition ) and the area, still in a natural depression, lacked adequate storm sewers.

Pastoralists arrived in the area shortly afterward with Charles Brockman setting up Boolatha Station in 1877 and the region experienced success in wool production until the 1930s when the overgrazing, drought and the great depression caused most businesses to fail.

However, the resort area began to decline before World War I and was gone by the time of the depression.

During the depression years of the thirties, many local men and area farmers

: Tropical cyclones form in the oceans if the conditions in the area are favorable, and depending on their strength and location, there are various terms by which they are called, such as tropical depression, tropical storm, hurricane and typhoon.

The watershed of the Pend Oreille in the Newport-Oldtown area is extremely limited, due to a small depression of no more than, which begins one-half mile to the west and south of the river.

The raphe nucleus is an area located in the pons of the brainstem that is the principal site of the synthesis of the neurotransmitter serotonin, which plays an important role in mood regulation, particularly when stress is associated with depression and anxiety.

In 1625 Farnham was again subject to an outbreak of the plague which, together with a severe decline in the local woollen industry ( the local downland wool being unsuitable for the newly fashionable worsted ) led by the 1640s to a serious economic depression in the area.

' Dull weather ' is a common expression incorporated with overcast stratocumulus days, which usually occur either in a warm sector between a warm and cold front in a depression, or in an area of high pressure, in the latter case, sometimes persisting over a specific area for several days.

The narrowest definition of Scafell Pike begins at the ridge of Mickledore in the south, takes in the wide, stony summit area and ends at the next depression, Broad Crag Col, c. 920 m ( 3, 030 ft ).

The combined effect of these two mechanisms is for the Earth's surface in the area of extension to subside, creating a geographical depression which is then often infilled with water and / or sediments.

During the 1840s, the felt hat industry went into depression ; the recession affected Denton, with wages in the area falling by 35 % and only 12 hat manufacturers remaining in Denton.

In winter, the male selects an area of ground, usually a small open space between the stunted trees of the mallee, and scrapes a depression about three metres across and just under a metre deep in the sandy soil by raking backwards with his feet.

In a study of older adults, those who volunteered were significantly higher on life satisfaction and will to live, and significantly lower in depression, anxiety, and somatization.

This creates further impairment because the left hemisphere in depressed individuals functions at lower levels of activity than people without depression .< ref name =" speechtherapy ">" Expressive Aphasia: Effective Home Treatment.

Lesbians who view themselves with male standards of female beauty may experience lower self-esteem, eating disorders, and higher incidence of depression.

It is speculated to have a role in depression, as some depressed patients are seen to have lower concentrations of metabolites of serotonin in their cerebrospinal fluid and brain tissue.

The mean phenotype of the gamodemes collection is lower than that of the panmictic " original "-which is known as inbreeding depression.

An analysis of over 200 social studies that " high religiousness predicts a rather lower risk of depression and drug abuse and fewer suicide attempts, and more reports of satisfaction with life and a sense of well-being.

" A review of 498 studies published in peer-reviewed journals concluded that a large majority of these studies showed a positive correlation between religious commitment and higher levels of perceived well-being and self-esteem, and lower levels of hypertension, depression and clinical delinquency.

Perimenopausal women in the Women ’ s Health Initiative who received estrogen had significantly lower coronary artery calcification compared to the women who didn ’ t take estrogen .” As Dr. Rubinow states, “ given the mortality and morbidity associated with depression and heart disease, and the tremendous increase in risk of these disorders during the perimenopause, it is critical that we identify those women who will be helped by estradiol .”

Hibernation is a state of inactivity and metabolic depression in animals, characterized by lower body temperature, slower breathing, and / or lower metabolic rate.

Each seed is enclosed by a very hard fruitcase, consisting of a cupule or depression in the rachis and a tough lower glume.

The April 1965 flood of the Upper Mississippi River affected the lower part of old Carver and deepened the depression.

The freezing point of a solution is lower than that of the pure solvent, and the freezing-point depression ( ΔT ) is directly proportional to the amount concentration for dilute solutions.

In spite of lower subjective rating, that is, feeling that they performed worse, no clinically relevant differences were observed in the objective cognitive performance in a group of people treated for depression with sertraline for 1. 5 years as compared to healthy controls.

It resembles barbiturate poisoning, but with increased motor difficulties and a lower incidence of cardiac or respiratory depression.

Altocumulus is also commonly found between the warm and cold fronts in a depression, although this is often hidden by lower clouds.

At the lower part of the acetabulum is the acetabular notch, which is continuous with a circular depression, the acetabular fossa, at the bottom of the cavity of the acetabulum.

They also had lower rates of depression, higher social capital, and less alcohol abuse.

Side effects of melatonin may include disturbance of sleep, nightmares, daytime sleepiness and depression, though the current tendency to use lower doses has decreased such complaints.

While the maroon Romeo records apparently sold well enough to be fairly easy to find, the black label and blue label Romeo's are rather harder to find, apparently indicating Kress ' lower record sales during the height of the depression.

Despite that, some more carefully conducted studies show a clear link to depression and lower visual-spatial reasoning skills.

Cyclical underemployment refers to the tendency for the capacity utilisation rate of firms ( and therefore of their demand for labor ) to be lower at times of recession and / or depression.

Opening of NMDA channels ( which relates to the level of cellular depolarization ) leads to a rise in post-synaptic Ca < sup > 2 +</ sup > concentration and this has been linked to long term potentiation, LTP ( as well as to protein kinase activation ); strong depolarization of the post-synaptic cell completely displaces the magnesium ions that block NMDA ion channels and allows calcium ions to enter a cell – probably causing LTP, while weaker depolarization only partially displaces the Mg < sup > 2 +</ sup > ions, resulting in less Ca < sup > 2 +</ sup > entering the post-synaptic neuron and lower intracellular Ca < sup > 2 +</ sup > concentrations ( which activate protein phosphatases and induce long-term depression, LTD ).