This leads Irenaeus to the somewhat startling notion that Adam and Eve died on the same day that they disobeyed, namely, on a Friday, as a parallel to the death of Christ on Good Friday ; ;

It had been hoped that patient adherence to antipsychotics would be higher with the atypicals, but a 2008 review found that the data have failed to substantiate the notion that novel antipsychotic drug use leads to improved medication compliance and favorable clinical outcomes.

This leads to the notion of an internal groupoid in a category.

The vagueness of the intuitionistic notion of truth often leads to misinterpretations about its meaning.

The generalization of these three properties to more abstract vector spaces leads to the notion of norm.

Russell's paradox, which shows that the notion of the set of all those sets that do not contain themselves leads to a contradiction, was instrumental in the development of modern logic and set theory.

Thus, the general notion of a statistical ensemble with nearest-neighbor interactions leads to Markov random fields, which again find broad applicability ; for example in Hopfield networks.

Elliott argues that this mistaken notion of his role as king ultimately leads to Richard's failure.

4 ) Similarly, the Moore – Smith theory of convergence via nets, as supplemented by Kelley's notion of a universal net, leads to the criterion that a space is compact if and only if each universal net on the space converges.

Marston positioned that there is a male notion of freedom that is inherently anarchic and violent and an opposing female notion based on " Love Allure " that leads to an ideal state of submission to loving authority.

This is a particularly unfortunate choice as it leads to confusion with the notion of a complex structure, which often has the same coordinate expression as Ω but represents a very different structure.

This notion of one ( multiplicity ) culture to an organization leads to the classification of culture along its path of emergence into nascent, adolescent, and mature types, each of which is distinct in terms of the pattern of the three cognitive components and behavior.

Tits later reworked the foundational aspects of the theory of buildings using the notion of a chamber system, encoding the building solely in terms of adjacency properties of simplices of maximal dimension ; this leads to simplifications in both spherical and affine cases.

The further question of what is the structure of the coarse quotient space leads to the notion of a smooth stack.

Carroll disclaims the notion that Christian anti-Judaism leads inevitably to the Shoah perpetrated by National Socialism, but he argues that Church's long history of " Jew-hatred " ( his term ) laid the foundation for Hitler's crimes.

This leads to the radical notion that there is no such thing as a " doer ".

This can easily be expressed in terms of a commutative diagram, and thus leads to the notion of a medial magma object in a category with a Cartesian product.

The notion of stratified negation leads to a very effective operational semantics for stratified programs in terms of the stratified least fixpoint, that is obtained by iteratively applying the fixpoint operator to each stratum of the program, from the lowest one up.

Meanwhile, his notion that we can begin to enjoy our eternal salvation through our earthly successes leads in later generations to " a mysticism of consolation ".

This leads to the notion that the points of the stack should carry automorphisms themselves, and this in turn gives rise to the notion of a stack as a certain kind of " category fibered in groupoids ".

This leads to the questions of the relevant notion of " possibility ": is the scenario described in premise 3 possible in the sense that is suggested in premise 2?

This important remark leads to the notion of sheaf cohomology, via derived functors.

It can be shown that dispersion-assisted selection leads to the greatest genetic advance ( ΔG

Also, as an individual plant can produce several thousand seeds ; each of the above criteria leads to A. thaliana being valued as a genetic model organism.

Huntington's disease ( HD ) is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and psychiatric problems.

Different antiseptics differ in how they cause bacteria to evolve, which leads to genetic defenses against particular compounds.

Somatic genetic mutation leads to a block in the production of functional protein from the mutant allele.

Xanthinuria is a rare genetic disorder where the lack of xanthine oxidase leads to high concentration of xanthine in blood and can cause health problems such as renal failure.

The reduction in a population's dispersal leads, over time, to increased genetic homogeneity.

The most common subtype is CDG-Ia ( also referred to as PMM2-CDG ) where the genetic defect leads to the loss of phosphomannomutase 2, the enzyme responsible for the conversion of mannose-6-phosphate into mannose-1-phosphate.

Selection assisted by dispersion leads to maximum genetic advance ( see previous references ).

Animals of domestic origin sometimes can produce fertile hybrids with native, wild animals which leads to genetic pollution ( not a clear term itself ) in the naturally evolved wild gene pools, many times threatening rare species with extinction.

This leads to the cultural evolution of highly adaptive behaviors and technology alongside genetic evolution.

Simon suffers from the rare genetic disorder choroideremia, a condition that leads to progressive deterioration in eyesight and in its later stage, blindness.

Researchers have found this genetic variation in unrelated families with OCD, and that it leads to faulty transporter function and regulation.

In multicellular eukaryotic organisms, sympatric speciation is thought to be an uncommon but plausible process by which genetic divergence ( through reproductive isolation ) of various populations from a single parent species and inhabiting the same geographic region leads to the creation of new species.

The 19-month-old baby has the genetic condition spinal muscular atrophy, which leads to almost total paralysis.

This leads to a theory of the origin of psychotic symptoms – that they are associated with deviations in the subtle asymmetries of development of the cortex, and that the symptoms arise as confusions between thought and speech and through the abnormal attachment of meaning to perceived speech – and to its genetic basis in the change that led to the evolution of Homo sapiens as a species.

Hereditary hemorrhagic telangiectasia ( HHT ), also known as Osler-Weber-Rendu disease and Osler-Weber-Rendu syndrome, is a genetic disorder that leads to abnormal blood vessel formation in the skin, mucous membranes, and often in organs such as the lungs, liver and brain.

The main character, Agatha Heterodyne, at first seems to be nothing more than a struggling student at Transylvania Polygnostic University, but when Baron Klaus Wulfenbach and his son come to investigate irregularities at the university, a seemingly unrelated sequence of events leads to Agatha awakening to her family's genetic inheritance and their secrets.

* Wilson's disease, a genetic disorder that leads to toxic levels of copper in the body

Screening these out in advance leads to preadapted stocks of cryptic genetic variation.

The latter novel Lungbarrow shows Rassilon becoming increasingly tyrannical and violently crushing resistance to his reforms, which ultimately leads to the Other breaking with him and throwing himself into the genetic looms, leading to his later apparent reincarnation as the Doctor.

The possibility of understanding how a particular mutation leads to a given phenotype has important implications for human genetic diseases, as answering these questions could point scientists in the direction of a treatment or cure.

Somaclonal variation leads to the creation of additional genetic variability.

Conservation of genetic variability is important to the overall health of populations because decreased genetic variability leads to increased levels of inbreeding, and reduced fitness.