Ultimately, the cAMP second messenger system, through several downstream mechanisms, works by modulating the opening of plasmalemmal ion channels that allow positively charged ions such as Na < sup >+</ sup > and K < sup >+</ sup > to enter or exit the cytoplasm of the cell, thereby generating or inhibiting an action potential.

Ultimately, since R < sup > 3 </ sup > is not RP < sup > 3 </ sup >, there will be a problem with each of these approaches.

Ultimately, it is uncertain if lactic acid reduces fatigue through increased intracellular calcium or increases fatigue through reduced sensitivity of contractile proteins to Ca < sup > 2 +</ sup >.

Ultimately, the interrogative pronouns ( those beginning with wh in addition to the word how ), derive from the Proto-Indo-European root k < sup > w </ sup > o-or k < sup > w </ sup > i, the former of which was reflected in Proto-Germanic as χ < sup > w </ sup > a-or kh < sup > w </ sup > a -..

Ultimately, it is uncertain if lactic acid reduces fatigue through increased intracellular calcium or increases fatigue through reduced sensitivity of contractile proteins to Ca < sup > 2 +</ sup >.

Ultimately, most of the CO < sub > 2 </ sub > emitted by human activities will dissolve in the ocean ,< ref name = arch05 > Archer, D. ( 2005 ).

Ultimately, the NTSB attributed this crash to pilot error on the approach – for example the maximum flap setting of 40 degrees was never applied, which meant that the aircraft's speed was higher than V < sub > REF </ sub > as it crossed the runway threshold.

Ultimately there is no evidence to definitively prove either hypothesis .< ref name =" Sunset 96 "> Dodson, Aidan.

Ultimately, the name " University of Rochester " was retained .< ref >, University of Rochester Urged to Change Name </ i ></ ref >< ref > What's in a Name?

Ultimately, the case was dismissed as moot when the university amended its policies to accommodate the chapter .< ref >< em > The Alligator </ em >.

Ultimately, the system as it stood could not deal quickly enough with the large deficits and surpluses created in the balance of payments ; this has previously been attributed to increasing rigidity of wages ( particularly in terms of wage cuts ) brought about by the advent of unionized labor, but is now more likely thought of as an inherent fault with the system which came to light under the pressures of war and rapid technological change.

Scholars Diane Blair and Jay L. Barth continue: “ As long as Rockefeller led the Arkansas Republicans, the party had a progressive, reformist cast, and those whom Rockefeller had brought into the party continued to dominate party offices and shape presidential preferences until 1980 ,” when the nomination and election of Ronald W. Reagan of California as president and Frank D. White as governor moved power within the state GOP “ sharply to the right .” Ultimately the growth of the Republican Party was slower in Arkansas than in the other southern states in the post-segregation era.

Ultimately Washington decided that the Crips needed to be brought back under one umbrella organization ( as many new " sets " were formed after Washington and others went to jail ).

Ultimately, Hutchinson was brought to civil trial by the General Court in November 1637, presided over by Governor John Winthrop, on the charge of “ traducing the ministers ”.

Ultimately, it was not the attacks of Junius, but the return of Chatham that brought about his departure from politics.

Ultimately this statue of Juno was brought to Rome and placed in the sanctuary of Jupiter Optimus Maximus on the Capitoline Hill.

Ultimately, he argues, they are simply rumors, for no evidence has ever been brought forth.

Ultimately his persevering opposition to liberal views of religion brought on him a persecution that affected deeply his naturally delicate health.

Ultimately, Davout brought superior forces to bear in the late afternoon and pushed back the Austrians a short ways.

Ultimately, it was WMCA's earnest competition with rival WABC that brought about the defection of WMGM ( early 1962 ) and then WINS ( Spring 1965 ) to non-top 40 formats.

Ultimately US saxophonist and music educator Howie Smith was brought to Sydney on a grant from the Fulbright Program to set up the course.

Ultimately, it was the superior firepower of the Allies and their mastery of the skies that brought them victory.

" Ultimately he is brought down by Frankenstein just as he realizes that he was his own killer.

Ultimately, his focus on building a broadly left-wing green party in BC brought criticism from some members of the environmental movement in the province.

Ultimately, they brought in the militia to crush the rebellion and then hung its leaders.

Ultimately, it brought about the execution of her husband and manservant for sexual crimes.

Ultimately, Lil ' Slugger is a paranormal figment of Tsukiko's guilt and fear, brought inexplicably to life when the adult Tsukiko desperately needed to escape her responsibilities and then fed and nurtured by the fear of the populace.

Ultimately, both clubs reprised their position in the following season's competition with the inclusion of the Australian Institute of Sport evening out the numbers to 16, and as the first part of reforms to the competition set to be brought about in 2008.

Ultimately the Council decided not to take any action against McCoubrey, with a motion of censure brought in by the Alliance Party of Northern Ireland's David Alderdice defeated in the council.

Ultimately, complicated negotiations brought Harrison back into the group's activities.

Ultimately, the romance ended unconsummated ; afterwards, Goethe wrote a fictional depiction of these events, with some artistic changes, and published it under the title The Sorrows of Young Werther -- a ( still ) famous / infamous German book, which brought early renown to Goethe.

Ultimately, his views on slavery brought a storm of controversy as the nation entered the Civil War, earning him the enmity of several members of the Board of Trustees, including Amos Tuck ( 1835 ), a founding member of the Republican Party, and close friend of Abraham Lincoln.

Ultimately either the Trujillos would have been returned to power or the conflict would have produced conditions favorable to a takeover by Dominican elements responsive to Castro in Cuba.

) Ultimately, this erosion of power led to the Parliament Act of 1911 that marginalised the Lords ' role in the legislative process and crystallised the convention that had developed over the previous century that a Prime Minister cannot sit in the House of Lords.

Ultimately, the piece of Shabranigdo won, but Aqualord, using the last remnants of her power, sealed him into a block of magical ice within the Kataart Mountains.

Ultimately, the scattered references to " due process of law " in English law did not limit the power of the government ; about this, American law professor John Orth wrote that " the great phrases failed to retain their vitality.

Ultimately, the effect of mandrel wrapping on optical measurements depends on the propagating mode power distribution.

Ultimately it made for a very flexible system with a vast array of options, but could easily suffer from play balance problems if particular sets of rules were used together, since little effort was made to balance different variants against each other, and power creep in the later professions and spell lists was very much in evidence.

Ultimately, the goal is to be able to store heat both in industrial installations and in small combined heat and power plants such as those used in larger residential buildings.

Ultimately he became what French calls a " premature hippy " who " had great faith in the power of cosmic rays, and claimed that there are extraterrestrials with translucent flesh on the planet Altair.

Ultimately, Stoddard's power seems to derive more from his personality, political influence, and preaching ability, than from the force of his ideas.

Ultimately, the presiding magistrate's power over the assembly was nearly absolute.

Ultimately, power devolved to the hands of the Directory, an executive of five men who assumed power in France in year III of the French Revolution.

Ultimately, this prevented any moves towards separation while strengthening Catalonia's " federal " rights after the Commonwealth of Catalonia took power in 1914.

Ultimately, with the outbreak of the Russian Revolution of 1917, the Duma took a leading role in bringing about the Tsar's abdication, which led in turn to the abolition of the monarchy and the ascent to power of the Communists.

Ultimately, they helped each other understand their power and Piper was able to use Leo's sensing power to find Phoebe, while Leo was able to blow up the Siren using Piper's blasting power.

Ultimately, the AC power system prevailed.

Ultimately Nanda resigned, handing power to Chandragupta, and went into exile and was never heard of again.

Ultimately, strategies of accessing and influencing power are at the heart of what might first appear to be mere differences of communication styles.

Ultimately, it concluded that France had been the foreign power most involved in limiting the scale of the genocide once it got started, though it regretted that more had not been done.

Ultimately, adhering to Foucauldian notions of neoliberal governmentality, OSM indicates that whilst the State is no longer the locus of all power, its steering capacity should not be underestimated.

Ultimately, the Chosen One who could open the Matrix proved to be the youthful Hot Rod, who reclaimed the Matrix and was reformatted by its power into Rodimus Prime, before opening it within Unicron and releasing its power, which tore Unicron apart from within.