Upon exiting the endoplasmic reticulum and entering the Golgi apparatus via vesicular transport, a specific lysosomal tag, mannose 6-phosphate, is added to the peptides.

Upon entering the game, Bledsoe quickly moved the Patriots down the field and threw an 11-yard touchdown pass to David Patten to give the Patriots a 14 – 3 halftime lead.

Upon entering all service all three V bombers were initially painted in an overall silver finish, with the prominent under-nose H2S radomes on the Valiant and Vulcan left in black, however, this silver finish was later changed to one of anti-flash white, the RAF roundels being adjusted in shade, and made paler, to minimise the absorption of energy from the flash of detonating nuclear weapons.

Upon entering this coalition, Pitt said to Devonshire: " My Lord, I am sure I can save this country, and no one else can ".

Upon entering the CTV, astronauts could take off their launch and re-entry suits then proceed to chairs and beds for medical checks before being transported back to the crew quarters in the Operations and Checkout Building.

Upon entering higher education James worked as a school janitor, bellringer, carpenter, teacher, and preacher to help finance his education.

Upon both of them entering and tying for first place in a scientific contest at the University of Paris, Johann, unable to bear the " shame " of being compared as Daniel's equal, banned Daniel from his house.

Upon entering the Ying Wa College, new students are divided into five houses.

Upon entering the government, Allende relinquished his parliamentary seat for Valparaíso, which he had won in 1937.

Upon entering office in June 1970, Heath immediately set about trying to reverse Wilson's policy of ending Britain's military presence East of Suez.

Upon their arrival at Columbine, the duo met near Harris's car and armed two 20 pound ( 9 kg ) propane bombs before entering the cafeteria a few minutes prior to the beginning of the A lunch shift, placing the duffel bags containing the bombs inside.

Upon entering Oradour-sur-Glane, Sturmbannführer Diekmann had received orders from his regimental commander, Standartenführer Stadler, to only have the mayor of the town name thirty people who could serve as hostages in exchange for Sturmbannführer Kämpfe ; however, Diekmann instead ordered the population exterminated and the village burned to the ground.

Upon entering the US Open as the defending champion that year, he caused controversy when, after losing in the quarterfinals to Jim Courier, Sampras said that he was not disappointed and felt relieved that the pressure to defend his title was no longer on him.

) Upon entering office, President Woodrow Wilson segregated the United States Navy.

Upon entering his third season as Pistons coach, Saunders became the longest-tenured Pistons coach since Chuck Daly's nine-year tenure ( 1983 – 92 ).

Upon entering Nootka Sound, they found William Douglas and his ship the Iphigenia.

Upon entering the service of the Church he was placed at the head of the Catechetical School of Alexandria, where he lived and worked.

Upon entering either mode, the player will be able to select a course, find out which fruit will be the Lucky Fruit, and choose a Yoshi of desired colour to play as.

Upon entering Red Bank, County Route 520, along with County Route 11, head north on Broad Street and Route 35 heads northwest on two-lane Maple Avenue, which turns north and passes by numerous homes.

Upon entering Rahway, Route 35 crosses under the Northeast Corridor rail line just before ending at Route 27.

Upon entering Paramus, Route 4 has a cloverleaf interchange with County Route 62 ( Paramus Road / Passaic Street ).

Upon entering Folsom, the route passes over a Conrail Shared Assets Operations railroad line before coming to a cloverleaf interchange with US 322 ( Black Horse Pike ).

( Upon entering 6th grade, all students attend Peacock Jr. High ( Currently Peacock Middle School ) on the town's North Side.

Upon entering Salem at approximately 9 a. m., Morgan immediately took possession of the town and placed guards over the stores and streets.

Upon activating the amulet, the player is informed of his / her past by his / her dead father, after which the player is transported to the town of Crossroads, and Part I ends.

Of the three usual routes to Mecca, Ibn Battuta chose the least-travelled, which involved a journey up the Nile valley, then east to the Red Sea port of Aydhab, Upon approaching the town however, a local rebellion forced him to turn back.

Upon arriving in New York, he spent most of his first weeks in town trying to get in contact with Charlie Parker, despite being advised against doing so by several people he met during his quest, including saxophonist Coleman Hawkins.

Upon the 2001 Berlin administrative reform, Rathaus Schöneberg became the town hall for the newly constituted borough of Tempelhof-Schöneberg.

Upon receiving full control in 1713, the British soon moved the island's capital to the town of Basseterre in 1727, and St. Kitts quickly took off as a leader in sugar production in the Caribbean.

Upon his defeat he is seen sulking into town whilst the townsfolk pelt him with old fruit.

Upon learning from captured Prussian soldiers and a local area police chief that the Second Army was just from Saarbrücken near the town of Wissembourg, General Le Bœuf and Napoleon III decided to retreat to defensive positions.

Upon incorporation in 1894, the town was renamed Kensington.

Upon moving back to his home town, Hatcher finds it taken over by a gang of vicious Jamaican drug dealers, led by Screwface.

Upon the outskirts of Bedford the group turned eastward towards St Neots town.

Upon German entry in World War I, the town was heavily damaged due to German Schrecklichkeit policy.

" Upon reaching Summerville, Sherman was informed of a Confederate training camp some several miles up the river from town.

Upon Franklin's 1977 incorporation, the town began using the building as the town hall.

Upon arrival early in 1874, the villagers laid out the town site, including a few crude buildings.

Upon establishment of Benton County on September 30, 1836, Osage was deemed a suitable site for the county seat, and the town square was established as the home of county government the following year.

Upon division of the area into town lots and completion of all necessary legal procedures, the town of Lavonia was incorporated in 1880.

Upon finding out the children were all named Kell, they painted " Kell " on the sign, and the town had been Kell ever since.

Upon his return he guided the town through additional growth ; among other things he dug up trees along the Mackinaw River and hauled them to town where they were planted in public square.

Upon incorporation, Dyer was divided into three wards: The first ward consisted of all land within town limits lying west of Hart Street ; the second ward comprised the section east of Hart Street and south of Lincoln Highway ; and land north of Lincoln Highway and east of Hart Street formed the third ward.