Upon the arrest of the Gulf Cartel boss Osiel Cárdenas Guillen in 2003 and his extradition in 2007, the panorama for Los Zetas changed — they began to become synonymous with the Gulf Cartel, and their influences grew greater within the organization.

Upon the arrest of the Gulf Cartel boss Osiel Cárdenas Guillen in March 2003 and his extradition in 2007, the Zetas took a more active leadership role within the Gulf Cartel and their influence grew greater within the organization.

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