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The presence of such a gap suggested communication via chemical messengers traversing the synaptic cleft, and in 1921 German pharmacologist Otto Loewi ( 1873 – 1961 ) confirmed that neurons can communicate by releasing chemicals.
Furthermore, Otto Loewi is accredited with discovering acetylcholine ( ACh )— the first known neurotransmitter.
* December 25 – Otto Loewi, German-born pharmacologist, recipient of the Nobel Prize in Physiology or Medicine ( b. 1873 )
* June 3 – Otto Loewi, German-born pharmacologist, recipient of the Nobel Prize in Physiology or Medicine ( d. 1961 )
At this location, neuroscientist Otto Loewi first proved that nerves secrete substances called neurotransmitters, which have effects on receptors in target tissues.
Nobel Prize Laureates who taught at the University of Vienna include Robert Bárány, Julius Wagner-Jauregg, Hans Fischer, Karl Landsteiner, Erwin Schrödinger, Victor Franz Hess, Otto Loewi, Konrad Lorenz and Friedrich Hayek.
For his study of acetylcholine as agent in the chemical transmission of nerve impulses ( neurotransmission ) he shared the 1936 Nobel Prize in Physiology or Medicine with Otto Loewi.
Carl was invited to Graz to work with Otto Loewi to study the effect of the vagus nerve on the heart, Loewi would receive the Nobel Prize in Physiology or Medicine in 1936 for this work.
Otto Loewi ( 3 June 1873 – 25 December 1961 ) was a German born pharmacologist whose discovery of acetylcholine helped enhance medical therapy.
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